Publications by authors named "Kyle Orwig"

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Non-human primates as a translational model for the study of male reproductive health.
R Clayton Edenfield, Jasper C Bash, Lyndsey E Shorey-Kendrick, Rahul J D'Mello, Travis L Rice-Stitt, Kyle E Orwig

Nat Rev Urol· November 2025

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Identification of missense DMC1 variants in males with non-obstructive azoospermia.
Noor Ullah, Christopher Pombar, Rachel Hvasta-Gloria, Andrea J Berman, Michelle Malizio, Kyle E Orwig

J Assist Reprod Genet· November 2025

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A hidden protamine PTM code in sperm generates heterogeneous chromatin states and finetunes reproductive fitness.
Lindsay Moritz, Christopher J Woodilla, Ritvija Agrawal, Mashiat Rabbani, Samantha B Schon, Kyle E Orwig

bioRxiv· November 2025

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High completion rates for mail-in sperm cryopreservation across diverse US populations: a prospective cohort study.
Myriam Safrai, Andre Belarmino, Daniel Nolte, Kristin Smith, Joyce Reinecke, Kyle E Orwig

Fertil Steril· October 2025

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A Report on Testicular Tissue Cryopreservation for Fertility Preservation in Children: Confirmation of Germ Cell Preservation and Few Surgical Complications.
Christopher J McCauley, Kathryn L McElhinney, Barbara A Lockart, Lori Schmitt, Amanda Zielen, Kyle E Orwig

J Pediatr Surg· September 2025

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Is the time right for transplanting immature testicular tissue or cells to restore male fertility? Expert perspectives on clinical implementation of autotransplantation of cryopreserved testicular tissue or cells for fertility restoration.
Myriam Safrai, Ellen Goossens, Rod T Mitchell, Kyle E Orwig, Callista L Mulder

Best Pract Res Clin Obstet Gynaecol· September 2025

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SATINN v2: automated image analysis for mouse testis histology with multi-laboratory data integration†.
Ran Yang, Fritzie T Celino-Brady, Jessica E M Dunleavy, Katinka A Vigh-Conrad, Georgia R Atkins, Kyle E Orwig

Biol Reprod· May 2025

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The Case for Pre-Treatment Sperm Banking as Standard of Care for All Post-Pubertal Males with Cancer.
Leena Nahata, Joshua A Halpern, Kara Bendle, Olivia Frias, Kyle Orwig

J Adolesc Young Adult Oncol· April 2025

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Normal embryo development needs MEIG1-mediated sperm formation.
Yi Sheng, Yi Tian Yap, Wei Li, Opeyemi Dhikhirullahi, Changmin Niu, Kyle E Orwig

FASEB J· March 2025

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Ultrasound-Guided Rete Testis Approach to Sperm Aspiration and Spermatogonial Stem Cell Transplantation in Patients with Azoospermia.
Amanda Colvin Zielen, Karen A Peters, Gunapala Shetty, Deborah A Gross, Carol B Hanna, Kyle E Orwig

medRxiv· March 2025

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REPRODUCTIVE HEALTH IN TRANS AND GENDER-DIVERSE PATIENTS: Gonadal tissue cryopreservation in transgender and gender-diverse people.
Chatchanan Ausavarungnirun, Kyle E Orwig

Reproduction· December 2024

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Utilizing artificial intelligence in academic writing: an in-depth evaluation of a scientific review on fertility preservation written by ChatGPT-4.
Myriam Safrai, Kyle E Orwig

J Assist Reprod Genet· July 2024

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A 20-year overview of fertility preservation in boys: new insights gained through a comprehensive international survey.
Kathleen Duffin, Nina Neuhaus, Claus Yding Andersen, Virginie Barraud-Lange, Aude Braye, Kyle E Orwig

Hum Reprod Open· February 2024

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Deafening Silence of Male Infertility.
Catherine S Nam, Kevin J Campbell, Chiara Acquati, Raevti Bole, Ava Adler, Kyle E Orwig

Urology· December 2023

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Generation of two isogenic sickle cell disease induced pluripotent stem cell lines from testicular fibroblasts.
Mitchell R Harancher, Meena Sukhwani, Carlos A Castro, Michael H Hsieh, Kyle E Orwig

Stem Cell Res· December 2023

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A bioengineered in situ ovary (ISO) supports follicle engraftment and live-births post-chemotherapy.
Michael J Buckenmeyer, Meena Sukhwani, Aimon Iftikhar, Alexis L Nolfi, Ziyu Xian, Kyle E Orwig

J Tissue Eng· November 2023

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Human immature testicular tissue organ culture: a step towards fertility preservation and restoration.
Nagham Younis, Andre L Caldeira-Brant, Tianjiao Chu, Shtaywy Abdalla, Kyle E Orwig

Front Endocrinol (Lausanne)· September 2023

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Sperm chromatin structure and reproductive fitness are altered by substitution of a single amino acid in mouse protamine 1.
Lindsay Moritz, Samantha B Schon, Mashiat Rabbani, Yi Sheng, Ritvija Agrawal, Kyle E Orwig

Nat Struct Mol Biol· August 2023

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Dissecting the spermatogonial stem cell niche using spatial transcriptomics.
Shreya Rajachandran, Xin Zhang, Qiqi Cao, Andre L Caldeira-Brant, Xiangfan Zhang, Kyle E Orwig

Cell Rep· July 2023

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Transcriptional metabolic reprogramming implements meiotic fate decision in mouse testicular germ cells.
Xiaoyu Zhang, Yan Liu, Froylan Sosa, Sumedha Gunewardena, Peter A Crawford, Kyle E Orwig

Cell Rep· July 2023

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In vivo versus in silico assessment of potentially pathogenic missense variants in human reproductive genes.
Xinbao Ding, Priti Singh, Kerry Schimenti, Tina N Tran, Robert Fragoza, Kyle E Orwig

Proc Natl Acad Sci U S A· July 2023

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Effect of Distance From Fertility Center on Utilization of Fertility Preservation Referral in Men.
Daniel Pelzman, Gregory Dederer, Pouya Joolharzadeh, Christian Morrill, Kyle Orwig

JCO Oncol Pract· June 2023

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Perspectives: Methods for Evaluating Primate Spermatogonial Stem Cells.
Sarah K Munyoki, Kyle E Orwig

Methods Mol Biol· June 2023

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Genomic study of variants: prevalence and allelic heterogeneity in men with spermatogenic failure.
Sidra Qureshi, Jimmaline J Hardy, Christopher Pombar, Andrea J Berman, Agnieszka Malcher, Kyle E Orwig

Front Genet· May 2023

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DNALI1 interacts with the MEIG1/PACRG complex within the manchette and is required for proper sperm flagellum assembly in mice.
Yi Tian Yap, Wei Li, Qian Huang, Qi Zhou, David Zhang, Kyle E Orwig

Elife· April 2023

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