Publications by authors named "Kyle R Legate"

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PIP5KIγ90-generated phosphatidylinositol-4,5-bisphosphate promotes the uptake of Staphylococcus aureus by host cells.
Yong Shi, Anne Berking, Timo Baade, Kyle R Legate, Reinhard Fässler

Mol Microbiol· November 2021

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Histological comparison of arterial thrombi in mice and men and the influence of Cl-amidine on thrombus formation.
Julia Novotny, Sue Chandraratne, Tobias Weinberger, Vanessa Philippi, Konstantin Stark, Kyle R Legate

PLoS One· February 2018

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Sphingosine 1-Phosphate Produced by Sphingosine Kinase 2 Intrinsically Controls Platelet Aggregation In Vitro and In Vivo.
Nicole Urtz, Florian Gaertner, Marie-Luise von Bruehl, Sue Chandraratne, Faridun Rahimi, Kyle R Legate

Circ Res· July 2015

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Critical role of platelet glycoprotein ibα in arterial remodeling.
Sue Chandraratne, Marie-Luise von Bruehl, Judith-Irina Pagel, Konstantin Stark, Eike Kleinert, Kyle R Legate

Arterioscler Thromb Vasc Biol· March 2015

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The integrin adhesome: from genes and proteins to human disease.
Sabina E Winograd-Katz, Reinhard Fässler, Benjamin Geiger, Kyle R Legate

Nat Rev Mol Cell Biol· April 2014

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Sphingosine kinase 2 (Sphk2) regulates platelet biogenesis by providing intracellular sphingosine 1-phosphate (S1P).
Lin Zhang, Nicole Urtz, Florian Gaertner, Kyle R Legate, Tobias Petzold

Blood· August 2013

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Thrombocytosis as a response to high interleukin-6 levels in cGMP-dependent protein kinase I mutant mice.
Lin Zhang, Robert Lukowski, Florian Gaertner, Michael Lorenz, Kyle R Legate

Arterioscler Thromb Vasc Biol· August 2013

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A practical guide to quantify cell adhesion using single-cell force spectroscopy.
Jens Friedrichs, Kyle R Legate, Rajib Schubert, Mitasha Bharadwaj, Carsten Werner

Methods· April 2013

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Capillary and arteriolar pericytes attract innate leukocytes exiting through venules and 'instruct' them with pattern-recognition and motility programs.
Konstantin Stark, Annekathrin Eckart, Selgai Haidari, Anca Tirniceriu, Michael Lorenz, Kyle R Legate

Nat Immunol· January 2013

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Comparative phenotypic analysis of the two major splice isoforms of phosphatidylinositol phosphate kinase type Iγ in vivo.
Kyle R Legate, Dirk Montag, Ralph T Böttcher, Seiichiro Takahashi, Reinhard Fässler

J Cell Sci· December 2012

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Induction of membrane circular dorsal ruffles requires co-signalling of integrin-ILK-complex and EGF receptor.
S Babak Azimifar, Ralph T Böttcher, Sara Zanivan, Carsten Grashoff, Marcus Krüger, Kyle R Legate

J Cell Sci· January 2012

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Integrin adhesion and force coupling are independently regulated by localized PtdIns(4,5)2 synthesis.
Kyle R Legate, Seiichiro Takahashi, Navid Bonakdar, Ben Fabry, David Boettiger

EMBO J· November 2011

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PIPKI gamma 90 negatively regulates LFA-1-mediated adhesion and activation in antigen-induced CD4+ T cells.
Sarah A Wernimont, Kyle R Legate, William T N Simonson, Reinhard Fassler, Anna Huttenlocher

J Immunol· October 2010

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The tail of integrins, talin, and kindlins.
Markus Moser, Kyle R Legate, Roy Zent, Reinhard Fässler

Science· May 2009

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Genetic and cell biological analysis of integrin outside-in signaling.
Kyle R Legate, Sara A Wickström, Reinhard Fässler

Genes Dev· February 2009

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Mechanisms that regulate adaptor binding to beta-integrin cytoplasmic tails.
Kyle R Legate, Reinhard Fässler

J Cell Sci· January 2009

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What mouse mutants teach us about extracellular matrix function.
A Aszódi, Kyle R Legate, I Nakchbandi, R Fässler

Annu Rev Cell Dev Biol· December 2006

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Genetic analysis of beta1 integrin "activation motifs" in mice.
Aleksandra Czuchra, Hannelore Meyer, Kyle R Legate, Cord Brakebusch, Reinhard Fässler

J Cell Biol· September 2006

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ILK, PINCH and parvin: the tIPP of integrin signalling.
Kyle R Legate, Eloi Montañez, Oliver Kudlacek, Reinhard Fässler

Nat Rev Mol Cell Biol· January 2006

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The beta-subunit of the signal recognition particle receptor is a novel GTP-binding protein without intrinsic GTPase activity.
Kyle R Legate, David W Andrews

J Biol Chem· July 2003

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