Publications by authors named "Kyle Spinler"

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Identification of a Musashi2 translocation as a novel oncogene in myeloid leukemia.
Kyle Spinler, Michael Hamilton, Jeevisha Bajaj, Yutaka Shima, Emily Diaz

bioRxiv· December 2023

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A stem cell reporter based platform to identify and target drug resistant stem cells in myeloid leukemia.
Kyle Spinler, Jeevisha Bajaj, Takahiro Ito, Bryan Zimdahl, Michael Hamilton

Nat Commun· November 2020

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An in vivo genome-wide CRISPR screen identifies the RNA-binding protein Staufen2 as a key regulator of myeloid leukemia.
Jeevisha Bajaj, Michael Hamilton, Yutaka Shima, Kendall Chambers, Kyle Spinler

Nat Cancer· April 2020

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Cross-linked matrix rigidity and soluble retinoids synergize in nuclear lamina regulation of stem cell differentiation.
Irena L Ivanovska, Joe Swift, Kyle Spinler, Dave Dingal, Sangkyun Cho

Mol Biol Cell· July 2017

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SIRPA-Inhibited, Marrow-Derived Macrophages Engorge, Accumulate, and Differentiate in Antibody-Targeted Regression of Solid Tumors.
Cory M Alvey, Kyle R Spinler, Jerome Irianto, Charlotte R Pfeifer, Brandon Hayes

Curr Biol· July 2017

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Filomicelles from aromatic diblock copolymers increase paclitaxel-induced tumor cell death and aneuploidy compared with aliphatic copolymers.
Praful R Nair, S A Karthick, Kyle R Spinler, Mohammad R Vakili, Afsaneh Lavasanifar

Nanomedicine (Lond)· June 2016

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Macrophage engulfment of a cell or nanoparticle is regulated by unavoidable opsonization, a species-specific 'Marker of Self' CD47, and target physical properties.
Nisha G Sosale, Kyle R Spinler, Cory Alvey, Dennis E Discher

Curr Opin Immunol· August 2015

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Myosin-II repression favors pre/proplatelets but shear activation generates platelets and fails in macrothrombocytopenia.
Kyle R Spinler, Jae-Won Shin, Michele P Lambert, Dennis E Discher

Blood· January 2015

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Matrix elasticity regulates lamin-A,C phosphorylation and turnover with feedback to actomyosin.
Amnon Buxboim, Joe Swift, Jerome Irianto, Kyle R Spinler, P C Dave P Dingal

Curr Biol· August 2014

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Nuclear lamin stiffness is a barrier to 3D migration, but softness can limit survival.
Takamasa Harada, Joe Swift, Jerome Irianto, Jae-Won Shin, Kyle R Spinler

J Cell Biol· March 2014

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Contractile forces sustain and polarize hematopoiesis from stem and progenitor cells.
Jae-Won Shin, Amnon Buxboim, Kyle R Spinler, Joe Swift, David A Christian

Cell Stem Cell· January 2014

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Lamins regulate cell trafficking and lineage maturation of adult human hematopoietic cells.
Jae-Won Shin, Kyle R Spinler, Joe Swift, Joel A Chasis, Narla Mohandas

Proc Natl Acad Sci U S A· November 2013

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Mechanobiology of bone marrow stem cells: from myosin-II forces to compliance of matrix and nucleus in cell forms and fates.
Jae-Won Shin, Joe Swift, Irena Ivanovska, Kyle R Spinler, Amnon Buxboim

Differentiation· October 2013

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Nuclear lamin-A scales with tissue stiffness and enhances matrix-directed differentiation.
Joe Swift, Irena L Ivanovska, Amnon Buxboim, Takamasa Harada, P C Dave P Dingal, Kyle R Spinler

Science· August 2013

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Dynamic domains in polymersomes: mixtures of polyanionic and neutral diblocks respond more rapidly to changes in calcium than to pH.
Kyle Spinler, Aiwei Tian, David A Christian, Diego A Pantano, Tobias Baumgart

Langmuir· June 2013

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Myosin-II inhibition and soft 2D matrix maximize multinucleation and cellular projections typical of platelet-producing megakaryocytes.
Jae-Won Shin, Joe Swift, Kyle R Spinler, Dennis E Discher

Proc Natl Acad Sci U S A· July 2011

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