Publications by authors named "L Shihabuddin"

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The engineered AAV2-HBKO promotes non-invasive gene delivery to large brain regions beyond ultrasound targeted sites.
Rikke Hahn Kofoed, Kate Noseworthy, Kathleen Wu, Shuruthisai Sivadas, Lisa Stanek, Lamya S Shihabuddin

Mol Ther Methods Clin Dev· December 2022

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Glucosylceramide synthase inhibition reduces ganglioside GM3 accumulation, alleviates amyloid neuropathology, and stabilizes remote contextual memory in a mouse model of Alzheimer's disease.
James C Dodge, Thomas J Tamsett, Christopher M Treleaven, Tatyana V Taksir, Peter Piepenhagen, Lamya S Shihabuddin

Alzheimers Res Ther· February 2022

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Glucosylceramide in cerebrospinal fluid of patients with GBA-associated and idiopathic Parkinson's disease enrolled in PPMI.
Young Eun Huh, Hyejung Park, Ming Sum Ruby Chiang, Idil Tuncali, Ganqiang Liu, Lamya S Shihabuddin

NPJ Parkinsons Dis· November 2021

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Preclinical pharmacology of glucosylceramide synthase inhibitor venglustat in a GBA-related synucleinopathy model.
Catherine Viel, Jennifer Clarke, Can Kayatekin, Amy M Richards, Ming Sum R Chiang, Lamya S Shihabuddin

Sci Rep· October 2021

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Viral alpha-synuclein knockdown prevents spreading synucleinopathy.
Sindhu Menon, Rikke H Kofoed, Fadl Nabbouh, Kristiana Xhima, Yasmeen Al-Fahoum, Lamya S Shihabuddin

Brain Commun· October 2021

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