Publications by authors named "Lachlan Coin"

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Impact of human lifestyle on the pathogenic potential of urban wastewater.
Jiangping Wu, Yan Chen, Jiawei Zhao, Jake William O'Brien, Lachlan Coin

Environ Res· December 2025

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Dosage effect of copy number variation in epilepsy and ten regions of the human brain.
Tisham De, Lachlan Coin, Michael R Johnson

Sci Rep· December 2025

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Genome size estimation from long read overlaps.
Michael B Hall, Chenxi Zhou, Lachlan J M Coin

Bioinformatics· November 2025

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Genome graphs reveal the importance of structural variation in Mycobacterium tuberculosis evolution and drug resistance.
Aleix Canalda-Baltrons, Matthew Silcocks, Michael B Hall, Derrick Theys, Xuling Chang 常戌灵, Lachlan Coin

Nat Commun· November 2025

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Characterising the Transcriptomic Response to Interferon and Infection in European Domestic Ferret Respiratory Tissues Using Long-Read RNA Sequencing.
Rubaiyea Farrukee, Jessie J-Y Chang, Jianshu Zhang, James B Barnes, Shu Xin Zhang, Lachlan J M Coin

Immunology· October 2025

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Invasive Streptococcus dysgalactiae subspecies equisimilis compared with Streptococcus pyogenes in Australia, 2011-23, and the emergence of a multi-continent stG62647 lineage: a retrospective clinical and genomic epidemiology study.
Ouli Xie, Leo Featherstone, An N T Nguyen, Andrew J Hayes, Miranda E Pitt, Lachlan J M Coin

Lancet Microbe· October 2025

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Finding the optimal regimen for treatment (FORT) in people with pulmonary disease: a multicentre, randomised, multi-arm, adaptive platform trial.
Tiffany Jong, Timothy Baird, Helen Louise Barr, Scott Bell, Theophile Bigirumurame, Lachlan J M Coin

BMJ Open· September 2025

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Development and verification of a novel tiling PCR method for long-range HIV-1 sequencing in a diagnostic setting.
Bethany A Horsburgh, Arunasingam Abayasingam, Frances Jenkins, Hui Li, Charles S P Foster, Lachlan Coin

Sci Rep· July 2025

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Temporal and geographical lineage dynamics of invasive Streptococcus pyogenes in Australia from 2011 to 2023: a retrospective, multicentre, clinical and genomic epidemiology study.
Ouli Xie, Rebecca H Chisholm, Leo Featherstone, An N T Nguyen, Andrew J Hayes, Lachlan J M Coin

Lancet Microbe· June 2025

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Characterisation of resistance selection against second-/last-line antibiotics in methicillin-resistant ATCC 43300 strain.
Anggia Prasetyoputri, Miranda E Pitt, Minh Duc Cao, Soumya Ramu, Angela Kavanagh, Lachlan J M Coin

JAC Antimicrob Resist· June 2025

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Utilizing Nanopore direct RNA sequencing of blood from patients with sepsis for discovery of co- and post-transcriptional disease biomarkers.
Jingni He, Devika Ganesamoorthy, Jessie J-Y Chang, Jianshu Zhang, Sharon L Trevor, Lachlan J M Coin

BMC Infect Dis· May 2025

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Genome graphs reveal the importance of structural variation in evolution and drug resistance.
Aleix Canalda-Baltrons, Matthew Silcocks, Michael B Hall, Derrick Theys, Xuling Chang, Lachlan Coin

bioRxiv· May 2025

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Peptide selectivity of killer cell immunoglobulin-like receptors differs with allotypic variation in HLA class I.
Philippa M Saunders, Patricia T Illing, Lachlan Coin, Shu Cheng Wong, Clare V L Oates

J Immunol· April 2025

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Plasma metabolomic signatures for copy number variants and COVID-19 risk loci in Northern Finland populations.
Tisham De, Lachlan Coin, Jethro Herberg, Michael R Johnson, Marjo-Riitta Järvelin

Sci Rep· April 2025

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A flexible framework for minimal biomarker signature discovery from clinical omics studies without library size normalisation.
Daniel Rawlinson, Chenxi Zhou, Myrsini Kaforou, Kim-Anh Lê Cao, Lachlan J M Coin

PLOS Digit Health· March 2025

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Using synthetic RNA to benchmark poly(A) length inference from direct RNA sequencing.
Jessie J-Y Chang, Xuan Yang, Haotian Teng, Jianshu Zhang, Benjamin Reames, Lachlan J M Coin

Gigascience· January 2025

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Benchmarking reveals superiority of deep learning variant callers on bacterial nanopore sequence data.
Michael B Hall, Ryan R Wick, Louise M Judd, An N Nguyen, Eike J Steinig, Lachlan Coin

Elife· October 2024

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Uncovering strain- and age-dependent innate immune responses to SARS-CoV-2 infection in air-liquid-interface cultured nasal epithelia.
Jessie J-Y Chang, Samantha L Grimley, Bang M Tran, Georgia Deliyannis, Carolin Tumpach, Lachlan J M Coin

iScience· June 2024

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Sustained transmission over two decades of a previously unrecognised MPT64 negative strain in Queensland, Australia: a whole genome sequencing study.
Arnold Bainomugisa, Sushil Pandey, Bridget O'Connor, Melanie Syrmis, David Whiley, Lachlan J M Coin

Lancet Reg Health West Pac· June 2024

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Host gene expression signatures to identify infection type and organ dysfunction in children evaluated for sepsis: a multicentre cohort study.
Luregn J Schlapbach, Devika Ganesamoorthy, Clare Wilson, Sainath Raman, Shane George, Lachlan J M Coin

Lancet Child Adolesc Health· May 2024

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Correction: Achievement of therapeutic antibiotic exposures using Bayesian dosing software in critically unwell children and adults with sepsis.
Ming G Chai, Quyen Tu, Menino O Cotta, Michelle J Bauer, Ross Balch, Lachlan Coin

Intensive Care Med· May 2024

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Achievement of therapeutic antibiotic exposures using Bayesian dosing software in critically unwell children and adults with sepsis.
Ming G Chai, Quyen Tu, Menino O Cotta, Michelle J Bauer, Ross Balch, Lachlan Coin

Intensive Care Med· April 2024

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MERITS: a web-based integrated PE/PPE protein database.
Zhijie He, Cong Wang, Xudong Guo, Heyun Sun, Yue Bi, Lachlan J M Coin

Bioinform Adv· March 2024

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Pangenome databases improve host removal and mycobacteria classification from clinical metagenomic data.
Michael B Hall, Lachlan J M Coin

Gigascience· January 2024

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Associations between Wastewater Microbiome and Population Smoking Rate Identified Using Wastewater-Based Epidemiology.
Jiangping Wu, Shuxin Zhang, Yan Chen, Jiawei Zhao, Tanjila Prosun, Lachlan J M Coin

Environ Health (Wash)· December 2023

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