Publications by authors named "Lachlan Gray"

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Modular Lentiviral Vectors for Highly Efficient Transgene Expression in Resting Immune Cells.
Christina Fichter, Anupriya Aggarwal, Andrew Kam Ho Wong, Samantha McAllery, Vennila Mathivanan, Lachlan R Gray

Viruses· June 2021

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Cell type-specific circular RNA expression in human glial cells.
Ashton Curry-Hyde, Lachlan G Gray, Bei Jun Chen, Uwe Ueberham, Thomas Arendt

Genomics· November 2020

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Identification of Specific Circular RNA Expression Patterns and MicroRNA Interaction Networks in Mesial Temporal Lobe Epilepsy.
Lachlan G Gray, James D Mills, Ashton Curry-Hyde, Sasha Devore, Daniel Friedman

Front Genet· September 2020

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Early transcriptome changes in response to chemical long-term potentiation induced via activation of synaptic NMDA receptors in mouse hippocampal neurons.
Nicola Bliim, Iryna Leshchyns'ka, Ryan Keable, Bei Jun Chen, Ashton Curry-Hyde, Lachlan Gray

Genomics· December 2019

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HIV latency can be established in proliferating and nonproliferating resting CD4+ T cells in vitro: implications for latency reversal.
Michael A Moso, Jenny L Anderson, Samantha Adikari, Lachlan R Gray, Georges Khoury

AIDS· February 2019

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Analysis of Clinical HIV-1 Strains with Resistance to Maraviroc Reveals Strain-Specific Resistance Mutations, Variable Degrees of Resistance, and Minimal Cross-Resistance to Other CCR5 Antagonists.
Jacqueline K Flynn, Paula Ellenberg, Renee Duncan, Anne Ellett, Jingling Zhou, Lachlan R Gray

AIDS Res Hum Retroviruses· December 2017

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Longitudinal Analysis of CCR5 and CXCR4 Usage in a Cohort of Antiretroviral Therapy-Naïve Subjects with Progressive HIV-1 Subtype C Infection.
Martin R Jakobsen, Kieran Cashin, Michael Roche, Jasminka Sterjovski, Anne Ellett, Lachlan R Gray

PLoS One· October 2017

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Toxicity and in vitro activity of HIV-1 latency-reversing agents in primary CNS cells.
Lachlan R Gray, Hung On, Emma Roberts, Hao K Lu, Michael A Moso

J Neurovirol· August 2016

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Strategies to target HIV-1 in the central nervous system.
Lachlan R Gray, Bruce J Brew, Melissa J Churchill

Curr Opin HIV AIDS· July 2016

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HIV integration and the establishment of latency in CCL19-treated resting CD4(+) T cells require activation of NF-κB.
Suha Saleh, Hao K Lu, Vanessa Evans, David Harisson, Jingling Zhou, Lachlan Gray

Retrovirology· July 2016

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A HIV-Tat/C4-binding protein chimera encoded by a DNA vaccine is highly immunogenic and contains acute EcoHIV infection in mice.
Khamis Tomusange, Danushka Wijesundara, Jason Gummow, Tamsin Garrod, Yanrui Li, Lachlan Gray

Sci Rep· June 2016

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Inhibition of catechol-O-methyl transferase (COMT) by tolcapone restores reductions in microtubule-associated protein 2 (MAP2) and synaptophysin (SYP) following exposure of neuronal cells to neurotropic HIV.
Ting Ting Lee, Gursharan Chana, Paul R Gorry, Anne Ellett, Chad A Bousman, Lachlan R Gray

J Neurovirol· October 2015

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Ex vivo response to histone deacetylase (HDAC) inhibitors of the HIV long terminal repeat (LTR) derived from HIV-infected patients on antiretroviral therapy.
Hao K Lu, Lachlan R Gray, Fiona Wightman, Paula Ellenberg, Gabriela Khoury

PLoS One· July 2015

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HIV-1 entry and trans-infection of astrocytes involves CD81 vesicles.
Lachlan R Gray, Stuart G Turville, Tina L Hitchen, Wan-Jung Cheng, Anne M Ellett

PLoS One· June 2015

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HIV-1 transcriptional regulation in the central nervous system and implications for HIV cure research.
Melissa J Churchill, Daniel J Cowley, Steve L Wesselingh, Paul R Gorry, Lachlan R Gray

J Neurovirol· June 2015

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Reliable genotypic tropism tests for the major HIV-1 subtypes.
Kieran Cashin, Lachlan R Gray, Katherine L Harvey, Danielle Perez-Bercoff, Guinevere Q Lee

Sci Rep· February 2015

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Is the central nervous system a reservoir of HIV-1?
Lachlan R Gray, Michael Roche, Jacqueline K Flynn, Steve L Wesselingh, Paul R Gorry

Curr Opin HIV AIDS· November 2014

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The NRTIs lamivudine, stavudine and zidovudine have reduced HIV-1 inhibitory activity in astrocytes.
Lachlan R Gray, Gilda Tachedjian, Anne M Ellett, Michael J Roche, Wan-Jung Cheng

PLoS One· November 2013

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Entinostat is a histone deacetylase inhibitor selective for class 1 histone deacetylases and activates HIV production from latently infected primary T cells.
Fiona Wightman, Hao K Lu, Ajantha E Solomon, Suha Saleh, Andrew N Harman, Lachlan Gray

AIDS· November 2013

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The magnitude of HIV-1 resistance to the CCR5 antagonist maraviroc may impart a differential alteration in HIV-1 tropism for macrophages and T-cell subsets.
Jacqueline K Flynn, Geza Paukovics, Miranda S Moore, Anne Ellett, Lachlan R Gray

Virology· July 2013

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A common mechanism of clinical HIV-1 resistance to the CCR5 antagonist maraviroc despite divergent resistance levels and lack of common gp120 resistance mutations.
Michael Roche, Hamid Salimi, Renee Duncan, Brendan L Wilkinson, Kelechi Chikere, Lachlan R Gray

Retrovirology· April 2013

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Is specific HIV eradication from the brain possible or needed?
Bruce J Brew, Lachlan Gray, Sharon Lewin, Melissa Churchill

Expert Opin Biol Ther· March 2013

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Reduced basal transcriptional activity of central nervous system-derived HIV type 1 long terminal repeats.
Lachlan R Gray, Daniel Cowley, Emma Crespan, Casey Welsh, Charlene Mackenzie

AIDS Res Hum Retroviruses· February 2013

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CoRSeqV3-C: a novel HIV-1 subtype C specific V3 sequence based coreceptor usage prediction algorithm.
Kieran Cashin, Lachlan R Gray, Martin R Jakobsen, Jasminka Sterjovski, Melissa J Churchill

Retrovirology· February 2013

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Macrophage-tropic HIV-1 variants from brain demonstrate alterations in the way gp120 engages both CD4 and CCR5.
Hamid Salimi, Michael Roche, Nicholas Webb, Lachlan R Gray, Kelechi Chikere

J Leukoc Biol· January 2013

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