Publications by authors named "Laila F Awad"

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Impact of trifluoromethyl Ugi adducts as anticancer agents: EGFR inhibition, apoptosis induction and miRNA up-regulation.
Mohammed Salah Ayoup, Eman Mamdouh, Saied M Soliman, Ibrahim Elghamry, Mohamed S Nafie, Laila F Awad

RSC Adv· June 2025

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Combating oxi-inflamm-aging: Passerini adducts tethered with 1,2,3-triazoles for enhanced antioxidant defense and 5-LOX inhibition.
Mohammed Salah Ayoup, Marwa Mohammed Rashwan, Saied M Soliman, Doaa A Ghareeb, Samah Ashraf, Laila F Awad

RSC Med Chem· April 2025

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Triggering Breast Cancer Apoptosis via Cyclin-Dependent Kinase Inhibition and DNA Damage by Novel Pyrimidinone and 1,2,4-Triazolo[4,3-]pyrimidinone Derivatives.
Mohamed N Abd Al Moaty, Yeldez El Kilany, Laila F Awad, Saied M Soliman, Assem Barakat

ACS Omega· May 2024

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Discovery of novel benzimidazole acyclic C-nucleoside DNA intercalators halting breast cancer growth.
Mohamed N Abd Al Moaty, Yeldez El Kilany, Laila Fathy Awad, Nihal Ahmed Ibrahim, Marwa M Abu-Serie

Arch Pharm (Weinheim)· January 2024

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Harnessing ROS-Induced Oxidative Stress for Halting Colorectal Cancer Thiazolidinedione-Based SOD Inhibitors.
Mohamed Nabil Abd Al Moaty, El Sayed H El Ashry, Laila Fathy Awad, Asmaa Mostafa, Marwa M Abu-Serie

ACS Omega· June 2022

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Enhancing the Anticancer Potential of Targeting Tumor-Associated Metalloenzymes via VEGFR Inhibition by New Triazolo[4,3-]pyrimidinone Acyclo C-Nucleosides Multitarget Agents.
Mohamed Nabil Abd Al Moaty, El Sayed Helmy El Ashry, Laila Fathy Awad, Nihal Ahmed Ibrahim, Marwa Muhammad Abu-Serie

Molecules· April 2022

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Halting colorectal cancer metastasis via novel dual nanomolar MMP-9/MAO-A quinoxaline-based inhibitors; design, synthesis, and evaluation.
Mohammed Salah Ayoup, Marwa M Abu-Serie, Laila F Awad, Mohamed Teleb, Hanan M Ragab

Eur J Med Chem· October 2021

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Fluorinated phenylalanines: synthesis and pharmaceutical applications.
Laila Fathy Awad, Mohammed Salah Ayoup

Beilstein J Org Chem· May 2020

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Structure-based design and optimization of pyrimidine- and 1,2,4-triazolo[4,3-a]pyrimidine-based matrix metalloproteinase-10/13 inhibitors via Dimroth rearrangement towards targeted polypharmacology.
El Sayed Helmy El Ashry, Laila Fathy Awad, Mohamed Teleb, Nihal Ahmed Ibrahim, Marwa M Abu-Serie

Bioorg Chem· March 2020

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Synthesis and activity against HBV of novel Tetra-seconucleoside analogues of dyphlline having the acyclic chains of ACV and HBG.
El Sayed H El Ashry, Laila F Awad, Nagwa Rashed, Adel Abdelrahman, Hana A Rasheed

Nucleosides Nucleotides Nucleic Acids· March 2008

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Synthesis of AZT analogues: 7-(3-azido-2-hydroxypropyl)-, 7-(3-amino-2-hydroxypropyl)-,7-(3-triazolyl-2-hydroxypropyl)theophylline.
El Sayed H El Ashry, Adel Abdel-Rahman, Nagwa Rashed, Laila F Awad, Hanaa A Rasheed

Nucleosides Nucleotides Nucleic Acids· March 2006

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