Publications by authors named "Lalit P Singh"

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Glyceraldehyde-3-phosphate dehydrogenase/1,3-bisphosphoglycerate-NADH as key determinants in controlling human retinal endothelial cellular functions: Insights from glycolytic screening.
Nicole Oska, Ahmed M Awad, Shaimaa Eltanani, Mohamed Shawky, Armaan Naghdi, Lalit Pukhrambam Singh

J Biol Chem· May 2025

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Serum Biochemical and Gene Expression Changes in the Spermatozoa of Buffalo Bulls Under Heat Stress.
Rashi Vasisth, Karpenahalli Ranganatha Sriranga, Meenakshi Chitkara, Ankita Gurao, Lalit Pratap Singh, Pawan Singh, Ranjit Singh Kataria

Biochem Genet· May 2025

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Transcriptomic analysis reveals molecular insights into lactation dynamics in Jakhrana goat mammary gland.
Mahesh Shivanand Dige, Ankita Gurao, Lalit Pratap Singh, Meenakshi Chitkara, Manoj Kumar Singh, Ranjit Singh Kataria

BMC Genomics· September 2024

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Correction: TXNIP mediates high glucose-induced mitophagic flux and lysosome enlargement in human retinal pigment epithelial cells.
Takhellambam S Devi, Thangal Yumnamcha, Fayi Yao, Mallika Somayajulu, Renu A Kowluru, Lalit P Singh

Biol Open· August 2022

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Differential Effects of Cytopathic Hypoxia on Human Retinal Endothelial Cellular Behavior: Implication for Ischemic Retinopathies.
Shaimaa El-Tanani, Thangal Yumnamcha, Lalit Pukhrambam Singh, Ahmed S Ibrahim

Int J Mol Sci· April 2022

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Potential Combination Drug Therapy to Prevent Redox Stress and Mitophagy Dysregulation in Retinal Müller Cells under High Glucose Conditions: Implications for Diabetic Retinopathy.
Lalit Pukhrambam Singh, Takhellambam S Devi

Diseases· December 2021

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Mitophagy, Ferritinophagy and Ferroptosis in Retinal Pigment Epithelial Cells Under High Glucose Conditions: Implications for Diabetic Retinopathy and Age-Related Retinal Diseases.
Lalit Pukhrambam Singh, Thangal Yumnamcha, Takhellambam S Devi

JOJ Ophthalmol· September 2021

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Relative Contribution of Different Mitochondrial Oxidative Phosphorylation Components to the Retinal Pigment Epithelium Barrier Function: Implications for RPE-Related Retinal Diseases.
Michael H Guerra, Thangal Yumnamcha, Lalit P Singh, Ahmed S Ibrahim

Int J Mol Sci· July 2021

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Real-Time Monitoring the Effect of Cytopathic Hypoxia on Retinal Pigment Epithelial Barrier Functionality Using Electric Cell-Substrate Impedance Sensing (ECIS) Biosensor Technology.
Michael H Guerra, Thangal Yumnamcha, Abdul-Shukkur Ebrahim, Elizabeth A Berger, Lalit Pukhrambam Singh

Int J Mol Sci· April 2021

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Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition).
Daniel J Klionsky, Amal Kamal Abdel-Aziz, Sara Abdelfatah, Mahmoud Abdellatif, Asghar Abdoli, Anurag Singh, Lalit P Singh, Rajat Singh, Shivendra V Singh, Shrawan K Singh, Sudha B Singh, Sunaina Singh, Surinder Pal Singh

Autophagy· January 2021

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Metabolic Dysregulation and Neurovascular Dysfunction in Diabetic Retinopathy.
Thangal Yumnamcha, Michael Guerra, Lalit Pukhrambam Singh, Ahmed S Ibrahim

Antioxidants (Basel)· December 2020

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Auranofin Mediates Mitochondrial Dysregulation and Inflammatory Cell Death in Human Retinal Pigment Epithelial Cells: Implications of Retinal Neurodegenerative Diseases.
Thangal Yumnamcha, Takhellembam Swornalata Devi, Lalit Pukhrambam Singh

Front Neurosci· October 2019

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TXNIP mediates high glucose-induced mitophagic flux and lysosome enlargement in human retinal pigment epithelial cells.
Takhellambam S Devi, Thangal Yumnamcha, Fayi Yao, Mallika Somayajulu, Renu A Kowluru, Lalit P Singh

Biol Open· April 2019

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Gene and Tissue Engineering For the Treatment of Diabetes and Its Retinal Complications: The Use of Nucleic Acid Constructs Bearing A Gene Promoter.
Lalit P Singh

Curr Trends Biomed Eng Biosci· April 2018

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Mitophagic Flux Deregulation, Lysosomal Destabilization and NLRP3 Inflammasome Activation in Diabetic Retinopathy: Potentials of Gene Therapy Targeting TXNIP and The Redox System.
Lalit Pukhrambam Singh, Thangal Yumnamcha, Takhellambam Swornalata Devi

Ophthalmol Res Rep· March 2018

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The Role of Txnip in Mitophagy Dysregulation and Inflammasome Activation in Diabetic Retinopathy: A New Perspective.
Lalit P Singh, Takhellambam S Devi, Thangal Yumnamcha

JOJ Ophthalmol· September 2017

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TXNIP regulates mitophagy in retinal Müller cells under high-glucose conditions: implications for diabetic retinopathy.
Takhellambam Swornalata Devi, Mallika Somayajulu, Renu Anjan Kowluru, Lalit Pukhrambam Singh

Cell Death Dis· May 2017

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Genetic and epigenetic modifications in the pathogenesis of diabetic retinopathy: a molecular link to regulate gene expression.
Priya Pradhan, Nisha Upadhyay, Archana Tiwari, Lalit P Singh

New Front Ophthalmol· October 2016

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Erratum to "epigenetic modifications and potential new treatment targets in diabetic retinopathy".
Lorena Perrone, Carmela Matrone, Lalit P Singh

J Ophthalmol· March 2015

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Epigenetic modifications and potential new treatment targets in diabetic retinopathy.
Lorena Perrone, Carmela Matrone, Lalit P Singh

J Ophthalmol· August 2014

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The NLRP3 inflammasome and diabetic cardiomyopathy : editorial to: "Rosuvastatin alleviates diabetic cardiomyopathy by inhibiting NLRP3 inflammasome and MAPK pathways in a type 2 diabetes rat model" by Beibei Luo et al.
Lalit P Singh

Cardiovasc Drugs Ther· February 2014

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Thioredoxin Interacting Protein (TXNIP) and Pathogenesis of Diabetic Retinopathy.
Lalit P Singh

J Clin Exp Ophthalmol· August 2013

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Critical role of TXNIP in oxidative stress, DNA damage and retinal pericyte apoptosis under high glucose: implications for diabetic retinopathy.
Takhellambam S Devi, Ken-Ichi Hosoya, Tetsuya Terasaki, Lalit P Singh

Exp Cell Res· April 2013

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Molecular intricacies and the role of ER stress in diabetes.
Muthuswamy Balasubramanyam, Lalit P Singh, Sampathkumar Rangasamy

Exp Diabetes Res· October 2012

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TXNIP links innate host defense mechanisms to oxidative stress and inflammation in retinal Muller glia under chronic hyperglycemia: implications for diabetic retinopathy.
Takhellambam S Devi, Icksoo Lee, Maik Hüttemann, Ashok Kumar, Kwaku D Nantwi, Lalit P Singh

Exp Diabetes Res· July 2012

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