Publications by authors named "Lam Leduy"

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The function of MYC in base excision repair protects against RAS-induced senescence.
Camila C F Faraco, Wanting Zhu, Anne-Marie Fortier, Zubaidah M Ramdzan, Elise Vickridge, Lam Leduy

Nucleic Acids Res· July 2025

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The BCL11A transcription factor stimulates the enzymatic activities of the OGG1 DNA glycosylase.
Tetiana Petrachkova, Olha Soldatkina, Lam Leduy, Alain Nepveu

Biol Chem· December 2024

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The function of BCL11B in base excision repair contributes to its dual role as an oncogene and a haplo-insufficient tumor suppressor gene.
Elise Vickridge, Camila C F Faraco, Fanny Lo, Hedyeh Rahimian, Zi Yang Liu, Lam Leduy

Nucleic Acids Res· January 2024

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The DNA repair function of BCL11A suppresses senescence and promotes continued proliferation of triple-negative breast cancer cells.
Elise Vickridge, Camila C F Faraco, Payman S Tehrani, Zubaidah M Ramdzan, Hedyeh Rahimian, Lam Leduy

NAR Cancer· December 2022

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CUT Domains Stimulate Pol β Enzymatic Activities to Accelerate Completion of Base Excision Repair.
Zubaidah M Ramdzan, Elise Vickridge, Li Li, Camila C F Faraco, Billel Djerir, Lam Leduy

J Mol Biol· February 2021

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CUX1 stimulates APE1 enzymatic activity and increases the resistance of glioblastoma cells to the mono-alkylating agent temozolomide.
Simran Kaur, Zubaidah M Ramdzan, Marie-Christine Guiot, Li Li, Lam Leduy

Neuro Oncol· March 2018

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The DNA repair function of CUX1 contributes to radioresistance.
Zubaidah M Ramdzan, Vasudeva Ginjala, Jordan B Pinder, Dudley Chung, Caroline M Donovan, Lam Leduy

Oncotarget· March 2017

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Special AT-rich Sequence-binding Protein 1 (SATB1) Functions as an Accessory Factor in Base Excision Repair.
Simran Kaur, Yan Coulombe, Zubaidah M Ramdzan, Lam Leduy, Jean-Yves Masson

J Biol Chem· October 2016

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CUX2 protein functions as an accessory factor in the repair of oxidative DNA damage.
Ranjana Pal, Zubaidah M Ramdzan, Simran Kaur, Philippe M Duquette, Richard Marcotte, Lam Leduy

J Biol Chem· September 2015

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The function of CUX1 in oxidative DNA damage repair is needed to prevent premature senescence of mouse embryo fibroblasts.
Zubaidah M Ramdzan, Ranjana Pal, Simran Kaur, Lam Leduy, Ginette Bérubé

Oncotarget· February 2015

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RAS transformation requires CUX1-dependent repair of oxidative DNA damage.
Zubaidah M Ramdzan, Charles Vadnais, Ranjana Pal, Guillaume Vandal, Chantal Cadieux, Lam Leduy

PLoS Biol· March 2014

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Long-range transcriptional regulation by the p110 CUX1 homeodomain protein on the ENCODE array.
Charles Vadnais, Arif A Awan, Ryoko Harada, Pier-Luc Clermont, Lam Leduy

BMC Genomics· April 2013

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Cut homeobox 1 causes chromosomal instability by promoting bipolar division after cytokinesis failure.
Laurent Sansregret, Charles Vadnais, Julie Livingstone, Nicholas Kwiatkowski, Arif Awan, Lam Leduy

Proc Natl Acad Sci U S A· February 2011

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Hyperphosphorylation by cyclin B/CDK1 in mitosis resets CUX1 DNA binding clock at each cell cycle.
Laurent Sansregret, David Gallo, Marianne Santaguida, Lam Leduy, Ryoko Harada

J Biol Chem· October 2010

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CUX1 transcription factor is a downstream effector of the proteinase-activated receptor 2 (PAR2).
Brian J Wilson, Ryoko Harada, Lam LeDuy, Morley D Hollenberg, Alain Nepveu

J Biol Chem· January 2009

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Proteolytic processing of cut homeobox 1 by neutrophil elastase in the MV4;11 myeloid leukemia cell line.
Brigitte Goulet, Yelena Markovic, Lam Leduy, Alain Nepveu

Mol Cancer Res· April 2008

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Genome-wide location analysis and expression studies reveal a role for p110 CUX1 in the activation of DNA replication genes.
Ryoko Harada, Charles Vadnais, Laurent Sansregret, Lam Leduy, Ginette Bérubé

Nucleic Acids Res· January 2008

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Carboxyl-terminal proteolytic processing of CUX1 by a caspase enables transcriptional activation in proliferating cells.
Mary Truscott, Jean-Bernard Denault, Brigitte Goulet, Lam Leduy, Guy S Salvesen

J Biol Chem· October 2007

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Increased expression and activity of nuclear cathepsin L in cancer cells suggests a novel mechanism of cell transformation.
Brigitte Goulet, Laurent Sansregret, Lam Leduy, Matthew Bogyo, Ekkehard Weber

Mol Cancer Res· September 2007

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The p110 isoform of the CDP/Cux transcription factor accelerates entry into S phase.
Laurent Sansregret, Brigitte Goulet, Ryoko Harada, Brian Wilson, Lam Leduy

Mol Cell Biol· March 2006

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The N-terminal region of the CCAAT displacement protein (CDP)/Cux transcription factor functions as an autoinhibitory domain that modulates DNA binding.
Mary Truscott, Lelia Raynal, Yufa Wang, Ginette Bérubé, Lam Leduy

J Biol Chem· November 2004

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CDP/Cux stimulates transcription from the DNA polymerase alpha gene promoter.
Mary Truscott, Lélia Raynal, Peter Premdas, Brigitte Goulet, Lam Leduy

Mol Cell Biol· April 2003

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Characterization of a tissue-specific CDP/Cux isoform, p75, activated in breast tumor cells.
Brigitte Goulet, Peter Watson, Madeleine Poirier, Lam Leduy, Ginette Bérubé

Cancer Res· November 2002

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