Publications by authors named "Lance Johnson"

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APOE4 to APOE2 allelic switching in mice improves Alzheimer's disease-related metabolic signatures, neuropathology and cognition.
Lesley R Golden, Dahlia S Siano, Isaiah O Stephens, Steven M MacLean, Kai Saito, Lance A Johnson

Nat Neurosci· December 2025

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Acute effects of lactate infusion on metabolism, AD biomarkers, and cognition: The LEAN study.
Riley E Kemna, Paul J Kueck, Anneka Blankenship, Casey S John, Chelsea N Johnson, Lance Johnson

Alzheimers Dement· December 2025

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Microglia-derived APOE2 improves remyelination even in the presence of endogenous APOE4.
Georgia L Nolt, Lesley R Golden, Shealee P Thorpe, Jessica L Funnell, Isaiah O Stephens, Lance A Johnson

J Neuroinflammation· December 2025

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Basic Science and Pathogenesis.
Lance A Johnson

Alzheimers Dement· December 2025

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APOE-Targeted Therapeutics for Alzheimer's Disease.
Hussein N Yassine, Cristelle Hugo, Bernadette O'Donovan, Isaiah O Stephens, Lance A Johnson

J Neurosci· November 2025

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Knockout of Perilipin-2 in Microglia Alters Lipid Droplet Accumulation and Response to Alzheimer's Disease Stimuli.
Isaiah O Stephens, Lance A Johnson

Cells· November 2025

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APOE4 reshapes the lipid droplet proteome and modulates microglial inflammatory responses.
Cassi M Friday, Isaiah O Stephens, Cathryn T Smith, Sangderk Lee, Diksha Satish, Lance A Johnson

Neurobiol Dis· August 2025

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Tau pathology reprograms glucose metabolism to support glutamatergic activity and excitatory imbalance.
Riley E Irmen, Sierra M Turner, J Andy Snipes, Holden C Williams, Velmurugan G Viswanathan, Lance A Johnson

bioRxiv· July 2025

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Genomic and cellular context-dependent expression of the human ELMO1 gene transcript variants.
Nobuyo Maeda, Lauren S Taylor, Melanie Nassar-Guifarro, Mohamed-Yahia S Monawar, Sierra M Dunn, Lance A Johnson

Gene· June 2025

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High-Resolution Spatial Profiling of Microglia Reveals Proximity Associated Immunometabolic Reprogramming in Alzheimer's Disease.
Kai Saito, Danielle S Goulding, Georgia L Nolt, Sophia H Dimas, Lauren C Moore, Lance A Johnson

bioRxiv· May 2025

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ATP-sensitive potassium channels alter glycolytic flux to modulate cortical activity and sleep.
Nicholas J Constantino, Caitlin M Carroll, Holden C Williams, Hemendra J Vekaria, Carla M Yuede, Lance A Johnson

Proc Natl Acad Sci U S A· February 2025

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alters the lipid droplet proteome and modulates droplet dynamics.
Cassi M Friday, Isaiah O Stephens, Cathryn T Smith, Sangderk Lee, Diksha Satish, Lance A Johnson

bioRxiv· December 2024

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Advancements in APOE and dementia research: Highlights from the 2023 AAIC Advancements: APOE conference.
Courtney M Kloske, Michael E Belloy, Elizabeth E Blue, Gregory R Bowman, Maria C Carrillo, Lance A Johnson

Alzheimers Dement· September 2024

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Enhancement of high-density lipoprotein-associated protease inhibitor activity prevents atherosclerosis progression.
Maura Mobilia, Alexander Karakashian, Khaga R Neupane, Olivia Hage, Callie Whitus, Lance A Johnson

Atherosclerosis· September 2024

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Alzheimer's and metabolism wed with IDO1.
Lance A Johnson, Shannon L Macauley

Science· August 2024

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Sex and genotype influence respiratory function under hypoxic and hypoxic-hypercapnic conditions.
Chase E Taylor, Laura E Mendenhall, Michael D Sunshine, Jessica N Wilson, Chris M Calulot, Lance A Johnson

J Neurophysiol· July 2024

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Kir6.2-K channels alter glycolytic flux to modulate cortical activity, arousal, and sleep-wake homeostasis.
Nicholas J Constantino, Caitlin M Carroll, Holden C Williams, Carla M Yuede, Patrick W Sheehan, Lance A Johnson

bioRxiv· February 2024

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Salvage First Metatarsophalangeal Joint Fusion with a Three-Dimensional-Printed Implant for Osseous Defects: A Case Series.
Lance J Johnson, Paul R Leatham, Coleman O Clougherty, Peter D Highlander

J Am Podiatr Med Assoc· January 2024

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ApoE isoform does not influence skeletal muscle regeneration in adult mice.
Benjamin I Burke, Jensen Goh, Fatmah A Albathi, Taylor R Valentino, Georgia L Nolt, Lance A Johnson

Front Physiol· November 2023

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Deconvolution reveals cell-type-specific transcriptomic changes in the aging mouse brain.
Yingxue Ren, Xue Wang, Shuwen Zhang, Hongru Hu, Zachary Quicksall, Lance A Johnson

Sci Rep· October 2023

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Apolipoprotein E genotype affects innate susceptibility to infection in aged male mice.
Jooyoung Cho, Katie L Alexander, Jessica L Ferrell, Lance A Johnson, Steven Estus

Infect Immun· September 2023

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Enhancement of High-Density Lipoprotein-Associated Protease Inhibitor Activity Prevents Atherosclerosis Progression.
Maura Mobilia, Alexander Karakashian, Callie Whitus, Khaga R Neupane, Lance A Johnson

bioRxiv· August 2023

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DNA-AgNC Loaded Liposomes for Measuring Cerebral Blood Flow Using Two-Photon Fluorescence Correlation Spectroscopy.
Xiaojin Wang, Mikkel B Liisberg, Georgia L Nolt, Xu Fu, Cecilia Cerretani, Lance A Johnson

ACS Nano· July 2023

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APOE modulates microglial immunometabolism in response to age, amyloid pathology, and inflammatory challenge.
Sangderk Lee, Nicholas A Devanney, Lesley R Golden, Cathryn T Smith, James L Schwartz, Lance A Johnson

Cell Rep· March 2023

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drives transcriptional heterogeneity and maladaptive immunometabolic responses of astrocytes.
Sangderk Lee, Holden C Williams, Amy A Gorman, Nicholas A Devanney, Douglas A Harrison, Lance A Johnson

bioRxiv· February 2023

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