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Publications by authors named "Langu Peng"

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Discovery of (1R,2R)-N-(4-(6-isopropylpyridin-2-yl)-3-(2-methyl-2H-indazol-5-yl)isothiazol-5-yl)-2-methylcyclopropanecarboxamide, a potent and orally efficacious mGlu5 receptor negative allosteric modulator.
Junliang Hao, Veronique Dehlinger, Adam M Fivush, Helene C E Rudyk, Thomas C Britton, Langu Peng

Bioorg Med Chem Lett· March 2013


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Discovery of 4-(5-methyloxazolo[4,5-b]pyridin-2-yl)-1,4-diazabicyclo[3.2.2]nonane (CP-810,123), a novel alpha 7 nicotinic acetylcholine receptor agonist for the treatment of cognitive disorders in schizophrenia: synthesis, SAR development, and in vivo efficacy in cognition models.
Christopher J O'Donnell, Bruce N Rogers, Brian S Bronk, Dianne K Bryce, Jotham W Coe, Langu Peng

J Med Chem· February 2010


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Synthesis and SAR studies of 1,4-diazabicyclo[3.2.2]nonane phenyl carbamates--subtype selective, high affinity alpha7 nicotinic acetylcholine receptor agonists.
Christopher J O'Donnell, Langu Peng, Brian T O'Neill, Eric P Arnold, Robert J Mather

Bioorg Med Chem Lett· August 2009


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