Publications by authors named "Lars Bolund"

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Spatial-Temporal Diversity of Extrachromosomal DNA Shapes Urothelial Carcinoma Evolution and the Tumor Immune Microenvironment.
Wei Lv, Yuchen Zeng, Conghui Li, Yuan Liang, Huiying Tao, Lars Bolund

Cancer Discov· May 2025

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An Overview and Comparative Analysis of CRISPR-SpCas9 gRNA Activity Prediction Tools.
Hao Yuan, Chunping Song, Huixin Xu, Ying Sun, Christian Anthon, Lars Bolund

CRISPR J· April 2025

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Spatial-Temporal Diversity of Extrachromosomal DNA Shapes Urothelial Carcinoma Evolution and Tumor-Immune Microenvironment.
Wei Lv, Yuchen Zeng, Conghui Li, Yuan Liang, Huiying Tao, Lars Bolund

Cancer Discov· March 2025

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Mapping the chromothripsis landscape in urothelial carcinoma unravels great intratumoral and intertumoral heterogeneity.
Yuchen Zeng, Wei Lv, Huiying Tao, Conghui Li, Shiqi Jiang, Lars Bolund

iScience· January 2025

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Extrachromosomal circular DNA orchestrates genome heterogeneity in urothelial bladder carcinoma.
Wei Lv, Xiaoguang Pan, Peng Han, Shuang Wu, Yuchen Zeng, Lars Bolund

Theranostics· September 2024

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From gut to liver: unveiling the differences of intestinal microbiota in NAFL and NASH patients.
Furong Huang, Bo Lyu, Fanci Xie, Fang Li, Yufeng Xing, Lars Bolund

Front Microbiol· April 2024

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Comparison of In-Frame Deletion, Homology-Directed Repair, and Prime Editing-Based Correction of Duchenne Muscular Dystrophy Mutations.
Xiaoying Zhao, Kunli Qu, Benedetta Curci, Huanming Yang, Lars Bolund

Biomolecules· May 2023

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Integrative genetic and single cell RNA sequencing analysis provides new clues to the amyotrophic lateral sclerosis neurodegeneration.
Hankui Liu, Liping Guan, Min Deng, Lars Bolund, Karsten Kristiansen

Front Neurosci· February 2023

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HIF1A Knockout by Biallelic and Selection-Free CRISPR Gene Editing in Human Primary Endothelial Cells with Ribonucleoprotein Complexes.
Camilla Blunk Brandt, Sofie Vestergaard Fonager, János Haskó, Rikke Bek Helmig, Søren Degn, Lars Bolund

Biomolecules· December 2022

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Author Correction: Endothelial cell heterogeneity and microglia regulons revealed by a pig cell landscape at single-cell level.
Fei Wang, Peiwen Ding, Xue Liang, Xiangning Ding, Camilla Blunk Brandt, Saga Bolund, Lars Bolund

Nat Commun· November 2022

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The single-cell expression profile of transposable elements and transcription factors in human early biparental and uniparental embryonic development.
Conghui Li, Yue Zhang, Lizhi Leng, Xiaoguang Pan, Depeng Zhao, Lars Bolund

Front Cell Dev Biol· November 2022

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A genetically modified minipig model for Alzheimer's disease with SORL1 haploinsufficiency.
Olav M Andersen, Nikolaj Bøgh, Anne M Landau, Gro G Pløen, Anne Mette G Jensen, Lars Bolund

Cell Rep Med· September 2022

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Massively targeted evaluation of therapeutic CRISPR off-targets in cells.
Xiaoguang Pan, Kunli Qu, Hao Yuan, Xi Xiang, Christian Anthon, Lars Bolund

Nat Commun· July 2022

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Endothelial cell heterogeneity and microglia regulons revealed by a pig cell landscape at single-cell level.
Fei Wang, Peiwen Ding, Xue Liang, Xiangning Ding, Camilla Blunk Brandt, Saga Bolund, Lars Bolund

Nat Commun· June 2022

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Circle-Seq reveals genomic and disease-specific hallmarks in urinary cell-free extrachromosomal circular DNAs.
Wei Lv, Xiaoguang Pan, Peng Han, Ziyu Wang, Weijia Feng, Lars Bolund

Clin Transl Med· April 2022

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Toward the massive genome of Proteus anguinus-illuminating longevity, regeneration, convergent evolution, and metabolic disorders.
Rok Kostanjšek, Børge Diderichsen, Hans Recknagel, Nina Gunde-Cimerman, Cene Gostinčar, Lars Bolund

Ann N Y Acad Sci· January 2022

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Genome-wide annotation of protein-coding genes in pig.
Max Karlsson, Evelina Sjöstedt, Per Oksvold, Åsa Sivertsson, Jinrong Huang, Lars Bolund

BMC Biol· January 2022

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The Dynamic Changes of Transcription Factors During the Development Processes of Human Biparental and Uniparental Embryos.
Chenxi Zhang, Conghui Li, Ling Yang, Lizhi Leng, Dragomirka Jovic, Lars Bolund

Front Cell Dev Biol· September 2021

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Comparative analysis of clonal evolution among patients with right- and left-sided colon and rectal cancer.
Santasree Banerjee, Xianxiang Zhang, Shan Kuang, Jigang Wang, Lei Li, Lars Bolund

iScience· July 2021

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Efficient correction of Duchenne muscular dystrophy mutations by SpCas9 and dual gRNAs.
Xi Xiang, Xiaoying Zhao, Xiaoguang Pan, Zhanying Dong, Jiaying Yu, Lars Bolund

Mol Ther Nucleic Acids· June 2021

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A porcine brain-wide RNA editing landscape.
Jinrong Huang, Lin Lin, Zhanying Dong, Ling Yang, Tianyu Zheng, Lars Bolund

Commun Biol· June 2021

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Enhancing CRISPR-Cas9 gRNA efficiency prediction by data integration and deep learning.
Xi Xiang, Giulia I Corsi, Christian Anthon, Kunli Qu, Xiaoguang Pan, Lars Bolund

Nat Commun· May 2021

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Single-Cell RNA Sequencing Maps Endothelial Metabolic Plasticity in Pathological Angiogenesis.
Katerina Rohlenova, Jermaine Goveia, Melissa García-Caballero, Abhishek Subramanian, Joanna Kalucka, Lars Bolund

Cell Metab· April 2020

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An atlas of the protein-coding genes in the human, pig, and mouse brain.
Evelina Sjöstedt, Wen Zhong, Linn Fagerberg, Max Karlsson, Nicholas Mitsios, Lars Bolund

Science· March 2020

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An Integrated Gene Expression Landscape Profiling Approach to Identify Lung Tumor Endothelial Cell Heterogeneity and Angiogenic Candidates.
Jermaine Goveia, Katerina Rohlenova, Federico Taverna, Lucas Treps, Lena-Christin Conradi, Lars Bolund

Cancer Cell· March 2020

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