Publications by authors named "Lars Helbig"

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Limited matching of the cardiac output response to the peripheral demand of heat stress and exercise.
Moritz Lampkemeyer, Jonas Kell, Veit Börß, Tobias Claussen, Fabian Spahiu, Lars C Helbig

Exp Physiol· May 2025

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Elevated frame rates during exercise echocardiography improve speckle-tracking success rate and augment deformation values.
Fabian Spahiu, Michelle Ottlik, Lars C Helbig, Eric J Stöhr

Am J Physiol Heart Circ Physiol· April 2025

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Surgical nonunion treatment of large-sized defects of femur and tibia based on the diamond concept.
Sebastian Findeisen, Louis Mennerat, Thomas Ferbert, Lars Helbig, Tim N Bewersdorf

Bone Jt Open· January 2025

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Use of Autologous Bone Graft with Bioactive Glass as a Bone Substitute in the Treatment of Large-Sized Bone Defects of the Femur and Tibia.
Sebastian Findeisen, Niklas Gräfe, Melanie Schwilk, Thomas Ferbert, Lars Helbig

J Pers Med· November 2023

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Editorial: Advances in non-union diagnostics, therapy and the understanding of its pathogenesis: current concepts from bench to bedside.
Patrick Haubruck, Michael C Tanner, Lars Helbig

Front Surg· September 2023

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Matched-Pair Analysis: Large-Sized Defects in Surgery of Lower Limb Nonunions.
Sebastian Findeisen, Melanie Schwilk, Patrick Haubruck, Thomas Ferbert, Lars Helbig

J Clin Med· June 2023

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Effect of Tricalcium Phosphate on Healing of Non-Unions: An Observational Study of over 400 Non-Unions.
Thomas Ferbert, Christina Münch, Sebastian Findeisen, William Pauly, Matthias Miska, Lars Helbig

Ther Clin Risk Manag· May 2023

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Tc-polyphosphonate labelling - Enhancement of a novel method for the quantification of osteogenic differentiation of MSCs in vitro.
Tobias Grossner, Lars Helbig, Gerhard Schmidmaier, Uwe Haberkorn, Tobias Gotterbarm

Injury· October 2022

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Efficacy of an Antibiotic Loaded Ceramic-Based Bone Graft Substitute for the Treatment of Infected Non-Unions.
Holger Freischmidt, Jonas Armbruster, Catharina Rothhaas, Nadine Titze, Thorsten Guehring, Lars Helbig

Biomedicines· October 2022

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Treatment of Infection-Related Non-Unions with Bioactive Glass-A Promising Approach or Just Another Method of Dead Space Management?
Holger Freischmidt, Jonas Armbruster, Catharina Rothhaas, Nadine Titze, Thorsten Guehring, Lars Helbig

Materials (Basel)· February 2022

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Systemic Administration of PTH Supports Vascularization in Segmental Bone Defects Filled with Ceramic-Based Bone Graft Substitute.
Holger Freischmidt, Jonas Armbruster, Emma Bonner, Thorsten Guehring, Dennis Nurjadi, Lars Helbig

Cells· August 2021

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The Influence of an Occult Infection on the Outcome of Autologous Bone Grafting During Surgical Bone Reconstruction: A Large Single-Center Case-Control Study.
Michael C Tanner, Raban Arved Heller, Andreas Grimm, Stefan Zimmermann, Maximilian Pilz, Lars Helbig

J Inflamm Res· March 2021

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Individualized Techniques of Implant Coating with an Antibiotic-Loaded, Hydroxyapatite/Calcium Sulphate Bone Graft Substitute.
Holger Freischmidt, Jonas Armbruster, Gregor Reiter, Paul Alfred Grützner, Lars Helbig

Ther Clin Risk Manag· July 2020

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A new sequential animal model for infection-related non-unions with segmental bone defect.
Lars Helbig, Thorsten Guehring, Nadine Titze, Dennis Nurjadi, Robert Sonntag

BMC Musculoskelet Disord· May 2020

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Bone morphogenetic proteins - 7 and - 2 in the treatment of delayed osseous union secondary to bacterial osteitis in a rat model.
Lars Helbig, Georg W Omlor, Adriana Ivanova, Thorsten Guehring, Robert Sonntag

BMC Musculoskelet Disord· July 2018

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Initial peri- and postoperative antibiotic treatment of infected nonunions: results from 212 consecutive patients after mean follow-up of 34 months.
Lars Helbig, Maren Bechberger, Riyadh Aldeeri, Adriana Ivanova, Patrick Haubruck

Ther Clin Risk Manag· January 2018

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Quantification of TGF-ß1, PDGF and IGF-1 cytokine expression after fracture treatment vs. non-union therapy via masquelet.
Christian Fischer, Julian Doll, Michael Tanner, Thomas Bruckner, Gerald Zimmermann, Lars Helbig

Injury· February 2016

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RIA fractions contain mesenchymal stroma cells with high osteogenic potency.
Pamela Kuehlfluck, Arash Moghaddam, Lars Helbig, Christopher Child, Britt Wildemann

Injury· December 2015

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A new animal model for delayed osseous union secondary to osteitis.
Lars Helbig, Thorsten Guehring, Svenja Rosenberger, Adriana Ivanova, Kathrin Kaeppler

BMC Musculoskelet Disord· November 2015

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Additional bone graft accelerates healing of clavicle non-unions and improves long-term results after 8.9 years: a retrospective study.
Marc Schnetzke, Christian Morbitzer, Sara Aytac, Matthias Erhardt, Christian Frank, Lars Helbig

J Orthop Surg Res· January 2015

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Establishment of a new methicillin resistant Staphylococcus aureus animal model of osteomyelitis.
Lars Helbig, Hans Georg Simank, Helga Lorenz, Cornelia Putz, Christoph Wölfl

Int Orthop· April 2014

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Implant stability in the treatment of MRSA bone implant infections with linezolid versus vancomycin in a rabbit model.
Kerstin Schroeder, Hans-Georg Simank, Helga Lorenz, Stefanie Swoboda, Heinrich K Geiss, Lars Helbig

J Orthop Res· February 2012

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Late activation of stress-activated protein kinases/c-Jun N-terminal kinases triggered by cisplatin-induced DNA damage in repair-defective cells.
Lars Helbig, Julia Damrot, Johannes Hülsenbeck, Beate Köberle, Anamaria Brozovic

J Biol Chem· April 2011

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Cisplatin sensitivity is related to late DNA damage processing and checkpoint control rather than to the early DNA damage response.
Anamaria Brozovic, Julia Damrot, Roman Tsaryk, Lars Helbig, Teodora Nikolova

Mutat Res· November 2009

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DNA replication arrest in response to genotoxic stress provokes early activation of stress-activated protein kinases (SAPK/JNK).
Julia Damrot, Lars Helbig, Wynand P Roos, Steve Q Barrantes, Bernd Kaina

J Mol Biol· February 2009

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