Publications by authors named "Lars N G Nilsson"

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Altered amyloid-β structure markedly reduces gliosis in the brain of mice harboring the Uppsala APP deletion.
María Pagnon de la Vega, Stina Syvänen, Vilmantas Giedraitis, Monique Hooley, Evangelos Konstantinidis, Lars N G Nilsson

Acta Neuropathol Commun· February 2024

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Cryo-EM of Aβ fibrils from mouse models find tg-APP fibrils resemble those found in patients with sporadic Alzheimer's disease.
Mara Zielinski, Fernanda S Peralta Reyes, Lothar Gremer, Sarah Schemmert, Benedikt Frieg, Lars N G Nilsson

Nat Neurosci· December 2023

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Contrast Enhanced Magnetic Resonance Imaging of Amyloid-β Plaques in a Murine Alzheimer's Disease Model.
Einar Sulheim, Marius WiderØe, Marcus Bäck, K Peter R Nilsson, Per Hammarström, Lars N G Nilsson

J Alzheimers Dis· May 2023

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Impaired astrocytic Ca signaling in awake-behaving Alzheimer's disease transgenic mice.
Knut Sindre Åbjørsbråten, Gry H E Syverstad Skaaraas, Céline Cunen, Daniel M Bjørnstad, Kristin M Gullestad Binder, Lars N G Nilsson

Elife· July 2022

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The deletion causes early onset autosomal dominant Alzheimer's disease by altering APP processing and increasing amyloid β fibril formation.
María Pagnon de la Vega, Vilmantas Giedraitis, Wojciech Michno, Lena Kilander, Gökhan Güner, Lars N G Nilsson

Sci Transl Med· August 2021

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A high cerebrospinal fluid soluble TREM2 level is associated with slow clinical progression of Alzheimer's disease.
Trine Holt Edwin, Kristi Henjum, Lars N G Nilsson, Leiv Otto Watne, Karin Persson

Alzheimers Dement (Amst)· December 2020

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Cerebrospinal fluid sTREM2 in Alzheimer's disease: comparisons between clinical presentation and AT classification.
Anne-Brita Knapskog, Kristi Henjum, Ane-Victoria Idland, Rannveig Sakshaug Eldholm, Karin Persson, Lars N G Nilsson

Sci Rep· September 2020

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Analyzing microglial-associated Aβ in Alzheimer's disease transgenic mice with a novel mid-domain Aβ-antibody.
Kristi Henjum, Vibeke Årskog, Charlotte B Jendresen, Tormod Fladby, Reidun Torp, Lars N G Nilsson

Sci Rep· June 2020

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Systemic LPS-induced Aβ-solubilization and clearance in AβPP-transgenic mice is diminished by heparanase overexpression.
Charlotte Jendresen, Andreas Digre, Hao Cui, Xiao Zhang, Israel Vlodavsky, Lars N G Nilsson

Sci Rep· March 2019

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Glial activation and inflammation along the Alzheimer's disease continuum.
Kaja Nordengen, Bjørn-Eivind Kirsebom, Kristi Henjum, Per Selnes, Berglind Gísladóttir, Lars N G Nilsson

J Neuroinflammation· February 2019

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CSF sTREM2 in delirium-relation to Alzheimer's disease CSF biomarkers Aβ42, t-tau and p-tau.
Kristi Henjum, Else Quist-Paulsen, Henrik Zetterberg, Kaj Blennow, Lars N G Nilsson

J Neuroinflammation· November 2018

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An improved CPRG colorimetric ligand-receptor signal transduction assay based on beta-galactosidase activity in mammalian BWZ-reporter cells.
Charlotte Jendresen, Michael R Daws, Lars N G Nilsson

J Pharmacol Toxicol Methods· September 2018

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The Alzheimer's disease risk factors apolipoprotein E and TREM2 are linked in a receptor signaling pathway.
Charlotte Jendresen, Vibeke Årskog, Michael R Daws, Lars N G Nilsson

J Neuroinflammation· March 2017

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Cerebrospinal fluid soluble TREM2 in aging and Alzheimer's disease.
Kristi Henjum, Ina S Almdahl, Vibeke Årskog, Lennart Minthon, Oskar Hansson, Lars N G Nilsson

Alzheimers Res Ther· April 2016

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Isobaric Quantification of Cerebrospinal Fluid Amyloid-β Peptides in Alzheimer's Disease: C-Terminal Truncation Relates to Early Measures of Neurodegeneration.
Magnus Rogeberg, Ina Selseth Almdahl, Marianne Wettergreen, Lars N G Nilsson, Tormod Fladby

J Proteome Res· November 2015

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Identification of amyloid beta mid-domain fragments in human cerebrospinal fluid.
Magnus Rogeberg, Marianne Wettergreen, Lars N G Nilsson, Tormod Fladby

Biochimie· June 2015

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Elevated mRNA-levels of gonadotropin-releasing hormone and its receptor in plaque-bearing Alzheimer's disease transgenic mice.
Syed Nuruddin, Gry Helen Enger Syverstad, Sveinung Lillehaug, Trygve B Leergaard, Lars N G Nilsson

PLoS One· April 2015

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Overexpression of heparanase lowers the amyloid burden in amyloid-β precursor protein transgenic mice.
Charlotte B Jendresen, Hao Cui, Xiao Zhang, Israel Vlodavsky, Lars N G Nilsson

J Biol Chem· February 2015

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Specific uptake of an amyloid-β protofibril-binding antibody-tracer in AβPP transgenic mouse brain.
Kristina Magnusson, Dag Sehlin, Stina Syvänen, Marie M Svedberg, Ola Philipson, Lars N G Nilsson

J Alzheimers Dis· April 2014

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Brainwide distribution and variance of amyloid-beta deposits in tg-ArcSwe mice.
Sveinung Lillehaug, Gry H Syverstad, Lars N G Nilsson, Jan G Bjaalie, Trygve B Leergaard

Neurobiol Aging· March 2014

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Lack of exon 10 in the murine tau gene results in mild sensorimotor defects with aging.
Astrid Gumucio, Lars Lannfelt, Lars N G Nilsson

BMC Neurosci· November 2013

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Transient OGG1, APE1, PARP1 and Polβ expression in an Alzheimer's disease mouse model.
Meryl S Lillenes, Mari Støen, Marta Gómez-Muñoz, Reidun Torp, Clara-Cecilie Günther, Lars N G Nilsson

Mech Ageing Dev· October 2013

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The Arctic AβPP mutation leads to Alzheimer's disease pathology with highly variable topographic deposition of differentially truncated Aβ.
Hannu Kalimo, Maciej Lalowski, Nenad Bogdanovic, Ola Philipson, Thomas D Bird, Lars N G Nilsson

Acta Neuropathol Commun· September 2013

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Elevated MARK2-dependent phosphorylation of Tau in Alzheimer's disease.
Gucci Jijuan Gu, Di Wu, Harald Lund, Dan Sunnemark, Alexander J Kvist, Lars N G Nilsson

J Alzheimers Dis· June 2013

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Heparanase overexpression impairs inflammatory response and macrophage-mediated clearance of amyloid-β in murine brain.
Xiao Zhang, Bo Wang, Paul O'Callaghan, Elina Hjertström, Juan Jia, Lars N G Nilsson

Acta Neuropathol· October 2012

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