Publications by authors named "Lars Ottosson"

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Growth failure in aggrecan deficiency is due to decreased extracellular matrix and impaired growth plate chondrocyte hypertrophy.
Ameya Bendre, Lars Ottosson, Marta Baroncelli, Zelong Dou, Ola Nilsson

Bone· November 2025

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Management and outcomes of foramen magnum stenosis in children with achondroplasia at a single center over 15 years.
Ulrika Sandvik, Edvin Ringvall, Katrin Klangemo, Sigrun Hallgrimsdottir, Alexandra Gkourogianni, Lars Ottosson

J Neurosurg Pediatr· November 2024

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Anti-Citrullinated Protein Antibody Reactivity towards Neutrophil-Derived Antigens: Clonal Diversity and Inter-Individual Variation.
Alexandra Cîrciumaru, Marcelo Gomes Afonso, Heidi Wähämaa, Akilan Krishnamurthy, Monika Hansson, Lars Ottosson

Biomolecules· March 2023

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The synovial microenvironment suppresses chondrocyte hypertrophy and promotes articular chondrocyte differentiation.
Michael Chau, Zelong Dou, Marta Baroncelli, Ellie B Landman, Ameya Bendre, Lars Ottosson

NPJ Regen Med· September 2022

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Rat perichondrium transplanted to articular cartilage defects forms articular-like, hyaline cartilage.
Zelong Dou, Daniel Muder, Marta Baroncelli, Ameya Bendre, Alexandra Gkourogianni, Lars Ottosson

Bone· October 2021

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Redox modifications of cysteine residues regulate the cytokine activity of HMGB1.
Huan Yang, Peter Lundbäck, Lars Ottosson, Helena Erlandsson-Harris, Emilie Venereau

Mol Med· June 2021

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Retraction Note to: Redox modification of cysteine residues regulates the cytokine activity of high mobility group box-1 (HMGB1).
Huan Yang, Peter Lundbäck, Lars Ottosson, Helena Erlandsson-Harris, Emilie Venereau

Mol Med· December 2020

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Expression of Concern to: Redox modification of cysteine residues regulates the cytokine activity of high mobility group box-1 (HMGB1).
Huan Yang, Peter Lundbäck, Lars Ottosson, Helena Erlandsson-Harris, Emilie Venereau

Mol Med· February 2020

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Neuroinflammation in Response to Intracerebral Injections of Different HMGB1 Redox Isoforms.
Hannah Aucott, Johan Lundberg, Henna Salo, Lena Klevenvall, Peter Damberg, Lars Ottosson

J Innate Immun· September 2019

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Therapeutic blockade of HMGB1 reduces early motor deficits, but not survival in the SOD1 mouse model of amyotrophic lateral sclerosis.
John D Lee, Ning Liu, Samantha C Levin, Lars Ottosson, Ulf Andersson

J Neuroinflammation· February 2019

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A novel high mobility group box 1 neutralizing chimeric antibody attenuates drug-induced liver injury and postinjury inflammation in mice.
Peter Lundbäck, Jonathan D Lea, Agnieszka Sowinska, Lars Ottosson, Camilla Melin Fürst

Hepatology· November 2016

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TLR4-dependant pro-inflammatory effects of HMGB1 on human adipocyte.
Manoj Kumar Gunasekaran, Anne-Laurence Virama-Latchoumy, Anne-Claire Girard, Cynthia Planesse, Alexis Guérin-Dubourg, Lars Ottosson

Adipocyte· October 2016

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Antibodies against High Mobility Group Box protein-1 (HMGB1) versus other anti-nuclear antibody fine-specificities and disease activity in systemic lupus erythematosus.
Lina Wirestam, Hanna Schierbeck, Thomas Skogh, Iva Gunnarsson, Lars Ottosson

Arthritis Res Ther· November 2015

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Monoclonal anti-HMGB1 (high mobility group box chromosomal protein 1) antibody protection in two experimental arthritis models.
Hanna Schierbeck, Peter Lundbäck, Karin Palmblad, Lena Klevenvall, Helena Erlandsson-Harris, Lars Ottosson

Mol Med· March 2012

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Redox modification of cysteine residues regulates the cytokine activity of high mobility group box-1 (HMGB1).
Huan Yang, Peter Lundbäck, Lars Ottosson, Helena Erlandsson-Harris, Emilie Venereau

Mol Med· March 2012

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Maternal MHC regulates generation of pathogenic antibodies and fetal MHC-encoded genes determine susceptibility in congenital heart block.
Linn S Strandberg, Aurelie Ambrosi, Maja Jagodic, Vijole Dzikaite, Peter Janson, Lars Ottosson

J Immunol· September 2010

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The alarmin HMGB1 acts in synergy with endogenous and exogenous danger signals to promote inflammation.
Hulda Sigridur Hreggvidsdottir, Therese Ostberg, Heidi Wähämaa, Hanna Schierbeck, Ann-Charlotte Aveberger, Lars Ottosson

J Leukoc Biol· September 2009

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Interferon-alpha induces up-regulation and nuclear translocation of the Ro52 autoantigen as detected by a panel of novel Ro52-specific monoclonal antibodies.
Linn Strandberg, Aurelie Ambrosi, Alexander Espinosa, Lars Ottosson, Maija-Leena Eloranta

J Clin Immunol· May 2008

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Structural, functional and immunologic characterization of folded subdomains in the Ro52 protein targeted in Sjögren's syndrome.
Lars Ottosson, Janosch Hennig, Alexander Espinosa, Susanna Brauner, Marie Wahren-Herlenius

Mol Immunol· February 2006

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Structural organization and Zn2+-dependent subdomain interactions involving autoantigenic epitopes in the Ring-B-box-coiled-coil (RBCC) region of Ro52.
Janosch Hennig, Lars Ottosson, Cecilia Andrésen, Linn Horvath, Vijay K Kuchroo

J Biol Chem· September 2005

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Ro/SSA autoantibodies directly bind cardiomyocytes, disturb calcium homeostasis, and mediate congenital heart block.
Stina Salomonsson, Sven-Erik Sonesson, Lars Ottosson, Saad Muhallab, Tomas Olsson

J Exp Med· January 2005

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A pH-induced modification of CII increases its arthritogenic properties.
Karin Lundberg, Lars Ottosson, Ewa Westman, Maria Sunnerhagen, Kjell Hultenby

J Autoimmun· September 2004

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Cloning and characterization of two human Ro52-specific monoclonal autoantibodies directed towards a domain associated with congenital heart block.
Stina Salomonsson, Lars Ottosson, Pär Säfsten, Danielle Hof, Hanna Brauner

J Autoimmun· March 2004

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