Publications by authors named "Lars Ruddigkeit"

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Identifying Lysophosphatidic Acid Acyltransferase β (LPAAT-β) as the Target of a Nanomolar Angiogenesis Inhibitor from a Phenotypic Screen Using the Polypharmacology Browser PPB2.
Marion Poirier, Mahendra Awale, Matthias A Roelli, Guy T Giuffredi, Lars Ruddigkeit

ChemMedChem· January 2019

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Biochanin A and prunetin improve epithelial barrier function in intestinal CaCo-2 cells via downregulation of ERK, NF-κB, and tyrosine phosphorylation.
Stefanie Piegholdt, Kathrin Pallauf, Tuba Esatbeyoglu, Nancy Speck, Karina Reiss, Lars Ruddigkeit

Free Radic Biol Med· May 2014

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Expanding the fragrance chemical space for virtual screening.
Lars Ruddigkeit, Mahendra Awale, Jean-Louis Reymond

J Cheminform· May 2014

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Visualization and virtual screening of the chemical universe database GDB-17.
Lars Ruddigkeit, Lorenz C Blum, Jean-Louis Reymond

J Chem Inf Model· January 2013

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Enumeration of 166 billion organic small molecules in the chemical universe database GDB-17.
Lars Ruddigkeit, Ruud van Deursen, Lorenz C Blum, Jean-Louis Reymond

J Chem Inf Model· November 2012

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Chemogenomic profiling provides insights into the limited activity of irreversible EGFR Inhibitors in tumor cells expressing the T790M EGFR resistance mutation.
Martin L Sos, Haridas B Rode, Stefanie Heynck, Martin Peifer, Florian Fischer, Lars Ruddigkeit

Cancer Res· February 2010

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