Publications by authors named "Lars Zender"

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An analysis of the distribution of bone and soft tissue sarcoma diagnoses and their disparities in Southwest Germany: a multicenter approach.
Branko Calukovic, Katrin Benzler, Mary E Carter, Adrien Daigeler, Johannes T Thiel, Lars Zender

Front Oncol· November 2025

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Correction: An analysis of the distribution of bone and soft tissue sarcoma diagnoses and their disparities in Southwest Germany: a multicenter approach.
Branko Calukovic, Katrin Benzler, Mary E Carter, Adrien Daigeler, Johannes T Thiel, Lars Zender

Front Oncol· November 2025

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Discovery of the First Highly Selective 1,4-dihydropyrido[3,4-]pyrazin-3(2H)-one MKK4 Inhibitor.
Leon Katzengruber, Pascal Sander, Stefan Zwirner, Alexander Rasch, Eric Eberlein, Lars Zender

J Med Chem· July 2025

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Variability of Metabolic Rate and Distribution Volume Quantification in Whole-Body Parametric PATLAK [F]-FDG PET/CT-A Prospective Trial in Patients with Lung Cancer.
Stephan Ursprung, Lars Zender, Patrick Ghibes, Florian Hagen, Konstantin Nikolaou

Diagnostics (Basel)· July 2025

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Targeting CD276 with Adapter-CAR T-cells provides a novel therapeutic strategy in small cell lung cancer and prevents CD276-dependent fratricide.
Beate Kristmann, Niels Werchau, Lakshmi Suresh, Elisabeth L Pezzuto, Sophia Scheuermann, Lars Zender

J Hematol Oncol· July 2025

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A "Ligand First" Approach toward Selective, Covalent JNK2/3 Inhibitors.
Valentin R Wydra, Nicole Plank, Stefan Zwirner, Roland Selig, Alexander Rasch, Lars Zender

J Med Chem· June 2025

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Actionable heterogeneity of hepatocellular carcinoma therapy-induced senescence.
Pujan Engels, Andras Szolek, Sebastian Hörner, Georgios Vavouras Syrigos, Kim Hebbel, Lars Zender

Cancer Immunol Immunother· May 2025

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Uncovering α-Selectivity for Liver X Receptor Agonists for Lipotoxic Cancer Therapies.
Júlia Galvez B Pedreira, Pascal Woelffing, Moritz Schwarz, Simon Ebner, Ramona Rudalska, Lars Zender

J Med Chem· April 2025

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Regulation of KIF23 by miR-107 controls replicative tumor cell fitness in mouse and human hepatocellular carcinoma.
Mirco Castoldi, Sanchari Roy, Carolin Angendohr, Rossella Pellegrino, Mihael Vucur, Lars Zender

J Hepatol· March 2025

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First-in-class ultralong-target-residence-time p38α inhibitors as a mitosis-targeted therapy for colorectal cancer.
Ramona Rudalska, Jule Harbig, Michael Forster, Pascal Woelffing, Aylin Esposito, Lars Zender

Nat Cancer· February 2025

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SarkoLife: quality of life in patients undergoing multimodal soft tissue sarcoma treatment.
Sebastian Hoffmann, Tabea Hoffmann, Vlatko Potkrajcic, Christoph K W Deinzer, Katrin Benzler, Lars Zender

World J Surg Oncol· January 2025

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Case report: Pulmonary Ewing sarcoma disguised as non-small cell lung cancer.
Mary E Carter, Alessia Benegiamo-Chilla, Linus D Kloker, Nikolas Paulsen, Vlatko Potkrajcic, Lars Zender

Front Oncol· November 2024

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PSMA-Guided Imaging and Therapy of Advanced Adenoid Cystic Carcinomas and Other Salivary Gland Carcinomas.
Nils F Trautwein, Andreas Brendlin, Gerald Reischl, Moritz Mattke, Frank Paulsen, Lars Zender

Cancers (Basel)· November 2024

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Autoimmunity Against Surfactant Protein B Is Associated with Pneumonitis During Checkpoint Blockade.
Nina Wyss, Fiamma Berner, Vincent Walter, Ann-Kristin Jochum, Mette T Purde, Lars Zender

Am J Respir Crit Care Med· October 2024

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Titration of RAS alters senescent state and influences tumour initiation.
Adelyne S L Chan, Haoran Zhu, Masako Narita, Liam D Cassidy, Andrew R J Young, Lars Zender

Nature· September 2024

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A real-world observation of patients with glioblastoma treated with a personalized peptide vaccine.
Pauline Latzer, Henning Zelba, Florian Battke, Annekathrin Reinhardt, Borong Shao, Lars Zender

Nat Commun· August 2024

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Author Correction: mTOR regulates MAPKAPK2 translation to control the senescence-associated secretory phenotype.
Nicolás Herranz, Suchira Gallage, Massimiliano Mellone, Torsten Wuestefeld, Sabrina Klotz, Lars Zender

Nat Cell Biol· June 2024

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Radiosensitizing Favors Response to Peptide Receptor Radionuclide Therapy in Patients With Highly Proliferative Neuroendocrine Malignancies: Preliminary Evidence From a Clinical Pilot Study.
Nils Florian Trautwein, Clemens Hinterleitner, Lena Sophie Kiefer, Stephan Singer, Sven Mattern, Lars Zender

Clin Nucl Med· March 2024

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Clinical management of NUT carcinoma (NC) in Germany: Analysis of survival, therapy response, tumor markers and tumor genome sequencing in 35 adult patients.
Linus D Kloker, Mirjana Sidiras, Tim Flaadt, Ines B Brecht, Christoph K W Deinzer, Lars Zender

Lung Cancer· March 2024

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First-in-class MKK4 inhibitors enhance liver regeneration and prevent liver failure.
Stefan Zwirner, Anan A Abu Rmilah, Sabrina Klotz, Bent Pfaffenroth, Philip Kloevekorn, Lars Zender

Cell· March 2024

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Small-molecule inhibition of MAP2K4 is synergistic with RAS inhibitors in -mutant cancers.
Robin A Jansen, Sara Mainardi, Matheus Henrique Dias, Astrid Bosma, Emma van Dijk, Lars Zender

Proc Natl Acad Sci U S A· February 2024

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Treatment modalities favoring outcome in well-differentiated neuroendocrine tumors G3.
Martina Hinterleitner, Ruben Pfeiffer, Nils F Trautwein, Bence Sipos, Stephan Singer, Lars Zender

Front Endocrinol (Lausanne)· January 2024

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Myasthenia gravis as initial presentation of a pancreatic neuroendocrine tumor: A case report.
Elena Stingu, Jerome-Maurice Dobrowolski, Paula Bombach, Dominik Nann, Stephan Singer, Lars Zender

Exp Ther Med· November 2023

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Diagnostic Approaches for Neuroendocrine Neoplasms of Unknown Primary (NEN-UPs) and Their Prognostic Relevance-A Retrospective, Long-Term Single-Center Experience.
Moritz Schmidt, Clemens Hinterleitner, Stephan Singer, Ulrich M Lauer, Lars Zender

Cancers (Basel)· August 2023

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Diagnostic Performance of Dynamic Whole-Body Patlak [F]FDG-PET/CT in Patients with Indeterminate Lung Lesions and Lymph Nodes.
Matthias Weissinger, Max Atmanspacher, Werner Spengler, Ferdinand Seith, Sebastian Von Beschwitz, Lars Zender

J Clin Med· June 2023

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