Publications by authors named "Laura Botti"

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ECM-Induced IL-23 Drives Immune Suppression in Breast Cancer via Regulating PD-1 on Tregs.
Giovanna Talarico, Mara Lecchi, Anna Zanichelli, Paola Portararo, Laura Botti

J Exp Clin Cancer Res· September 2025

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Intracellular Osteopontin Promotes the Release of TNFα by Mast Cells to Restrain Neuroendocrine Prostate Cancer.
Roberta Sulsenti, Giuseppina B Scialpi, Barbara Frossi, Laura Botti, Renata Ferri

Cancer Immunol Res· September 2024

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Mast cell heparanase promotes breast cancer stem-like features via MUC1/estrogen receptor axis.
Roberta Bongiorno, Mara Lecchi, Laura Botti, Oriana Bosco, Chiara Ratti

Cell Death Dis· September 2024

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Combined therapy targeting AR and EZH2 curbs castration-resistant prostate cancer enhancing anti-tumor T-cell response.
Irene Fischetti, Laura Botti, Roberta Sulsenti, Valeria Cancila, Claudia Enriquez

Epigenomics· March 2024

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ZEB1 shapes AML immunological niches, suppressing CD8 T cell activity while fostering Th17 cell expansion.
Barbara Bassani, Giorgia Simonetti, Valeria Cancila, Antonio Fiorino, Marilena Ciciarello, Laura Botti

Cell Rep· February 2024

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JMJD6 Shapes a Pro-tumor Microenvironment via ANXA1-Dependent Macrophage Polarization in Breast Cancer.
Bianca Cioni, Silvia Ratti, Annamaria Piva, Irene Tripodi, Matteo Milani, Laura Botti

Mol Cancer Res· June 2023

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Rewiring innate and adaptive immunity with TLR9 agonist to treat osteosarcoma.
Caterina Cascini, Chiara Ratti, Laura Botti, Beatrice Parma, Valeria Cancila

J Exp Clin Cancer Res· June 2023

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ATF3 Reprograms the Bone Marrow Niche in Response to Early Breast Cancer Transformation.
Milena Perrone, Claudia Chiodoni, Mara Lecchi, Laura Botti, Barbara Bassani

Cancer Res· January 2023

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Intracellular osteopontin protects from autoimmunity-driven lymphoma development inhibiting TLR9-MYD88-STAT3 signaling.
Celeste Rizzello, Valeria Cancila, Sabina Sangaletti, Laura Botti, Chiara Ratti

Mol Cancer· December 2022

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SCD5-dependent inhibition of SPARC secretion hampers metastatic spreading and favors host immunity in a TNBC murine model.
Maria Bellenghi, Giovanna Talarico, Laura Botti, Rossella Puglisi, Claudio Tabolacci

Oncogene· August 2022

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Neutrophil extracellular traps arm DC vaccination against NPM-mutant myeloproliferation.
Claudio Tripodo, Barbara Bassani, Elena Jachetti, Valeria Cancila, Claudia Chiodoni, Laura Botti

Elife· April 2022

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CD40 Activity on Mesenchymal Cells Negatively Regulates OX40L to Maintain Bone Marrow Immune Homeostasis Under Stress Conditions.
Barbara Bassani, Claudio Tripodo, Paola Portararo, Alessandro Gulino, Laura Botti

Front Immunol· October 2021

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SPARC regulation of PMN clearance protects from pristane-induced lupus and rheumatoid arthritis.
Sabina Sangaletti, Laura Botti, Alessandro Gulino, Daniele Lecis, Barbara Bassani

iScience· June 2021

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Intra-tumour heterogeneity of diffuse large B-cell lymphoma involves the induction of diversified stroma-tumour interfaces.
Sabina Sangaletti, Fabio Iannelli, Federica Zanardi, Valeria Cancila, Paola Portararo, Laura Botti

EBioMedicine· November 2020

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SPARC Is a New Myeloid-Derived Suppressor Cell Marker Licensing Suppressive Activities.
Sabina Sangaletti, Giovanna Talarico, Claudia Chiodoni, Barbara Cappetti, Laura Botti

Front Immunol· October 2020

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Infiltrating Mast Cell-Mediated Stimulation of Estrogen Receptor Activity in Breast Cancer Cells Promotes the Luminal Phenotype.
Maria Teresa Majorini, Valeria Cancila, Alice Rigoni, Laura Botti, Matteo Dugo

Cancer Res· June 2020

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Transcriptional Profiles and Stromal Changes Reveal Bone Marrow Adaptation to Early Breast Cancer in Association with Deregulated Circulating microRNAs.
Claudia Chiodoni, Valeria Cancila, Tiziana A Renzi, Milena Perrone, Andrea M Tomirotti, Laura Botti

Cancer Res· February 2020

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Trabectedin Overrides Osteosarcoma Differentiative Block and Reprograms the Tumor Immune Environment Enabling Effective Combination with Immune Checkpoint Inhibitors.
Chiara Ratti, Laura Botti, Valeria Cancila, Silvia Galvan, Ilaria Torselli

Clin Cancer Res· September 2017

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Persistent Immune Stimulation Exacerbates Genetically Driven Myeloproliferative Disorders via Stromal Remodeling.
Claudio Tripodo, Alessia Burocchi, Pier Paolo Piccaluga, Claudia Chiodoni, Paola Portararo, Laura Botti

Cancer Res· July 2017

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Imatinib Spares cKit-Expressing Prostate Neuroendocrine Tumors, whereas Kills Seminal Vesicle Epithelial-Stromal Tumors by Targeting PDGFR-β.
Elena Jachetti, Alice Rigoni, Lucia Bongiovanni, Ivano Arioli, Laura Botti

Mol Cancer Ther· February 2017

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Mesenchymal Transition of High-Grade Breast Carcinomas Depends on Extracellular Matrix Control of Myeloid Suppressor Cell Activity.
Sabina Sangaletti, Claudio Tripodo, Alessandra Santangelo, Nadia Castioni, Paola Portararo, Laura Botti

Cell Rep· September 2016

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TNF-Related Apoptosis-Inducing Ligand (TRAIL)-Armed Exosomes Deliver Proapoptotic Signals to Tumor Site.
Licia Rivoltini, Claudia Chiodoni, Paola Squarcina, Monica Tortoreto, Antonello Villa, Laura Botti

Clin Cancer Res· July 2016

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Osteopontin shapes immunosuppression in the metastatic niche.
Sabina Sangaletti, Claudio Tripodo, Sara Sandri, Ilaria Torselli, Caterina Vitali, Laura Botti

Cancer Res· September 2014

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Stromal niche communalities underscore the contribution of the matricellular protein SPARC to B-cell development and lymphoid malignancies.
Sabina Sangaletti, Claudio Tripodo, Paola Portararo, Matteo Dugo, Caterina Vitali, Laura Botti

Oncoimmunology· June 2014

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Scattering phase function measurements on single particles and on particle ensembles.
Alessandro Rossi, Laura Botti, Christian Sasse, Rainer Tamme

Appl Opt· December 2004

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