Publications by authors named "Laura Brandolini"

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Effects of CXCR1/2 Blockade with Ladarixin on Streptozotocin-Induced Type 1 Diabetes Mellitus and Peripheral Neuropathy and Retinopathy in Rat (Diabetes Metab J 2025;49:990-1005).
Serena Boccella, Andrea Maria Morace, Cristina Giorgio, Francesca Guida, Michela Perrone, Laura Brandolini

Diabetes Metab J· November 2025

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Effects of CXCR1/2 Blockade with Ladarixin on Streptozotocin-Induced Type 1 Diabetes Mellitus and Peripheral Neuropathy and Retinopathy in Rat.
Serena Boccella, Andrea Maria Morace, Cristina Giorgio, Francesca Guida, Michela Perrone, Laura Brandolini

Diabetes Metab J· September 2025

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Beyond inflammation: the multifaceted therapeutic potential of targeting the CXCL8-CXCR1/2 axis in type 1 diabetes.
Georgia Fousteri, Meghan Jones, Rubina Novelli, Serena Boccella, Laura Brandolini

Front Immunol· July 2025

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Evaluation of the gastrotolerability of ketoprofen, lysine, and gabapentin co-crystal administration in an in vitro model of gastric epithelium: a proteomic update.
Francesco D'Egidio, Laura Brandolini, Vanessa Castelli, Massimiliano Quintiliani, Andrea Aramini

PLoS One· July 2025

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A novel free fatty acid receptor agonist improving metabolic health in Drosophila models.
Kashi Brunetti, Elisabetta Catalani, Simona Del Quondam, Nicla Romano, Marcello Ceci, Laura Brandolini

Pharmacol Res· June 2025

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Reparixin as a Potential Antiepileptogenic Agent: Modulation of the CXCL1-CXCR1/2 Axis and Seizure Activity in a Kindling Rat Model of Temporal Lobe Epilepsy.
Nihan Çarçak, Nursima Mutlu, Elif Tuğçe Erdeve, Talat Taygun Turan, Özge Sarıyıldız, Laura Brandolini

Int J Mol Sci· March 2025

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Early transtympanic administration of rhBDNF exerts a multifaceted neuroprotective effect against cisplatin-induced hearing loss.
Anna Pisani, Rolando Rolesi, Veronica Mohamed-Hizam, Raffaele Montuoro, Gaetano Paludetti, Laura Brandolini

Br J Pharmacol· February 2025

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TNFα-CXCR1/2 partners in crime in insulin resistance conditions.
Vanessa Castelli, Housem Kacem, Laura Brandolini, Cristina Giorgio, Marta Sofia Scenna

Cell Death Discov· December 2024

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Tumor-Secreted Extracellular Vesicles Counteract Therapy Response by Triggering Inflammatory Mesenchymal Stem Cell Development.
Crescenzo Massaro, Hilal N Sensoy, Manon Mulders, Celine De Schrijver, Cristina Gómez-Martín, Laura Brandolini

Clin Cancer Res· October 2024

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Combination Drug Therapy for the Management of Chronic Neuropathic Pain.
Serena Boccella, Lidia De Filippis, Cristina Giorgio, Laura Brandolini, Meghan Jones

Biomolecules· December 2023

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Intranasal delivery of NGF rescues hearing impairment in aged SAMP8 mice.
Vanessa Castelli, Michele d'Angelo, Francesca Zazzeroni, Davide Vecchiotti, Edoardo Alesse, Laura Brandolini

Cell Death Dis· September 2023

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Ketoprofen, lysine and gabapentin co-crystal magnifies synergistic efficacy and tolerability of the constituent drugs: Pre-clinical evidences towards an innovative therapeutic approach for neuroinflammatory pain.
Andrea Aramini, Gianluca Bianchini, Samuele Lillini, Mara Tomassetti, Niccolò Pacchiarotti, Laura Brandolini

Biomed Pharmacother· July 2023

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C5aR1 signaling triggers lung immunopathology in COVID-19 through neutrophil extracellular traps.
Bruna M Silva, Giovanni F Gomes, Flavio P Veras, Seppe Cambier, Gabriel Vl Silva, Laura Brandolini

J Clin Invest· June 2023

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Differential Effects of Nonsteroidal Anti-Inflammatory Drugs in an In Vitro Model of Human Leaky Gut.
Michele d'Angelo, Laura Brandolini, Mariano Catanesi, Vanessa Castelli, Cristina Giorgio

Cells· February 2023

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Paclitaxel binds and activates C5aR1: A new potential therapeutic target for the prevention of chemotherapy-induced peripheral neuropathy and hypersensitivity reactions.
Laura Brandolini, Michele d'Angelo, Rubina Novelli, Vanessa Castelli, Cristina Giorgio

Cell Death Dis· May 2022

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Inflammation-Independent Antinociceptive Effects of DF2755A, a CXCR1/2 Selective Inhibitor: A New Potential Therapeutic Treatment for Peripheral Neuropathy Associated to Non-Ulcerative Interstitial Cystitis/Bladder Pain Syndrome.
Laura Brandolini, Andrea Aramini, Gianluca Bianchini, Anna Ruocco, Riccardo Bertini

Front Pharmacol· April 2022

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Intravitreal Administration of rhNGF Enhances Regenerative Processes in a Zebrafish Model of Retinal Degeneration.
Pasquale Cocchiaro, Vincenzo Di Donato, Davide Rubbini, Rodolfo Mastropasqua, Marcello Allegretti, Laura Brandolini

Front Pharmacol· March 2022

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The CXCR1/CXCR2 Inhibitor Reparixin Alters the Development of Myelofibrosis in the Mice.
Paola Verachi, Francesca Gobbo, Fabrizio Martelli, Andrea Martinelli, Giuseppe Sarli, Laura Brandolini

Front Oncol· March 2022

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MicroRNAs Expression in Response to rhNGF in Epithelial Corneal Cells: Focus on Neurotrophin Signaling Pathway.
Chiara Compagnoni, Veronica Zelli, Andrea Bianchi, Antinisca Di Marco, Roberta Capelli, Laura Brandolini

Int J Mol Sci· March 2022

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CXCL1-CXCR1/2 signaling is induced in human temporal lobe epilepsy and contributes to seizures in a murine model of acquired epilepsy.
Rossella Di Sapia, Till S Zimmer, Valentina Kebede, Silvia Balosso, Teresa Ravizza, Laura Brandolini

Neurobiol Dis· October 2021

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S-Carboxymethyl Cysteine Protects against Oxidative Stress and Mitochondrial Impairment in a Parkinson's Disease In Vitro Model.
Mariano Catanesi, Laura Brandolini, Michele d'Angelo, Maria Grazia Tupone, Elisabetta Benedetti

Biomedicines· October 2021

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CXCR1/2 Inhibitor Ladarixin Ameliorates the Insulin Resistance of 3T3-L1 Adipocytes by Inhibiting Inflammation and Improving Insulin Signaling.
Vanessa Castelli, Laura Brandolini, Michele d'Angelo, Cristina Giorgio, Margherita Alfonsetti

Cells· September 2021

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L-Methionine Protects against Oxidative Stress and Mitochondrial Dysfunction in an In Vitro Model of Parkinson's Disease.
Mariano Catanesi, Laura Brandolini, Michele d'Angelo, Elisabetta Benedetti, Maria Grazia Tupone

Antioxidants (Basel)· September 2021

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Taurine and oxidative stress in retinal health and disease.
Vanessa Castelli, Antonella Paladini, Michele d'Angelo, Marcello Allegretti, Flavio Mantelli, Laura Brandolini

CNS Neurosci Ther· April 2021

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Emerging Role of C5 Complement Pathway in Peripheral Neuropathies: Current Treatments and Future Perspectives.
Cristina Giorgio, Mara Zippoli, Pasquale Cocchiaro, Vanessa Castelli, Giustino Varrassi, Laura Brandolini

Biomedicines· April 2021

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