Publications by authors named "Laura Caldinelli"

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Glycine-gated extrasynaptic NMDARs activated during glutamate spillover drive burst firing in nigral dopamine neurons.
Sofian Ringlet, Zoraide Motta, Laura Vandries, Vincent Seutin, Kevin Jehasse, Laura Caldinelli

Prog Neurobiol· June 2025

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Structural characterization of PHOX2B and its DNA interaction shed light on the molecular basis of the +7Ala variant pathogenicity in CCHS.
Donatella Diana, Luciano Pirone, Luigi Russo, Gianluca D'Abrosca, Manoj Madheswaran, Laura Caldinelli

Chem Sci· June 2024

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Effect of l-serine and magnesium ions on the functional properties of human phosphoserine phosphatase and its pathogenetic variants.
Francesco Marchesani, Valeria Buoli Comani, Stefano Bruno, Andrea Mozzarelli, Mauro Carcelli, Laura Caldinelli

Biochim Biophys Acta Mol Basis Dis· March 2024

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Biochemical and cellular studies of three human 3-phosphoglycerate dehydrogenase variants responsible for pathological reduced L-serine levels.
Giulia Murtas, Elena Zerbini, Valentina Rabattoni, Zoraide Motta, Laura Caldinelli

Biofactors· February 2024

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The D-amino acid oxidase-carbon nanotubes: evaluation of cytotoxicity and biocompatibility of a potential anticancer nanosystem.
Elena Rosini, Marta Boreggio, Matteo Verga, Laura Caldinelli, Loredano Pollegioni

3 Biotech· July 2023

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Molecular insights into the role of the polyalanine region in mediating PHOX2B aggregation.
Luciano Pirone, Laura Caldinelli, Simona Di Lascio, Rocco Di Girolamo, Sonia Di Gaetano

FEBS J· July 2019

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Cellular prion protein neither binds to alpha-synuclein oligomers nor mediates their detrimental effects.
Pietro La Vitola, Marten Beeg, Claudia Balducci, Giulia Santamaria, Elena Restelli, Laura Caldinelli

Brain· February 2019

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Human d-amino acid oxidase: The inactive G183R variant.
Giulia Murtas, Laura Caldinelli, Pamela Cappelletti, Silvia Sacchi, Loredano Pollegioni

Biochim Biophys Acta Proteins Proteom· July 2018

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Alpha-synuclein oligomers impair memory through glial cell activation and via Toll-like receptor 2.
Pietro La Vitola, Claudia Balducci, Milica Cerovic, Giulia Santamaria, Edoardo Brandi, Laura Caldinelli

Brain Behav Immun· March 2018

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Assays of D-Amino Acid Oxidase Activity.
Elena Rosini, Laura Caldinelli, Luciano Piubelli

Front Mol Biosci· January 2018

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Regulating levels of the neuromodulator d-serine in human brain: structural insight into pLG72 and d-amino acid oxidase interaction.
Leila Birolo, Silvia Sacchi, Giovanni Smaldone, Gianluca Molla, Gabriella Leo, Laura Caldinelli

FEBS J· September 2016

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Structure-function relationships in human d-amino acid oxidase variants corresponding to known SNPs.
Pamela Cappelletti, Luciano Piubelli, Giulia Murtas, Laura Caldinelli, Mattia Valentino

Biochim Biophys Acta· September 2015

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D-amino acid oxidase-nanoparticle system: a potential novel approach for cancer enzymatic therapy.
Adriana Bava, Rosalba Gornati, Francesca Cappellini, Laura Caldinelli, Loredano Pollegioni

Nanomedicine (Lond)· November 2013

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One single method to produce native and Tat-fused recombinant human α-synuclein in Escherichia coli.
Laura Caldinelli, Diego Albani, Loredano Pollegioni

BMC Biotechnol· April 2013

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Characterization of human DAAO variants potentially related to an increased risk of schizophrenia.
Laura Caldinelli, Silvia Sacchi, Gianluca Molla, Marco Nardini, Loredano Pollegioni

Biochim Biophys Acta· March 2013

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Structure-function relationships in human D-amino acid oxidase.
Silvia Sacchi, Laura Caldinelli, Pamela Cappelletti, Loredano Pollegioni, Gianluca Molla

Amino Acids· November 2012

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Biosensors for D-amino acid detection.
Silvia Sacchi, Elena Rosini, Laura Caldinelli, Loredano Pollegioni

Methods Mol Biol· January 2012

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Effect of ligand binding on human D-amino acid oxidase: implications for the development of new drugs for schizophrenia treatment.
Laura Caldinelli, Gianluca Molla, Luisa Bracci, Barbara Lelli, Silvia Pileri

Protein Sci· August 2010

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FAD binding in glycine oxidase from Bacillus subtilis.
Laura Caldinelli, Mattia Pedotti, Laura Motteran, Gianluca Molla, Loredano Pollegioni

Biochimie· April 2010

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Recombinant production of eight human cytosolic aminotransferases and assessment of their potential involvement in glyoxylate metabolism.
Stefano Donini, Manuela Ferrari, Chiara Fedeli, Marco Faini, Ilaria Lamberto, Laura Caldinelli

Biochem J· August 2009

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Relevance of weak flavin binding in human D-amino acid oxidase.
Laura Caldinelli, Gianluca Molla, Silvia Sacchi, Mirella S Pilone, Loredano Pollegioni

Protein Sci· April 2009

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Relevance of the flavin binding to the stability and folding of engineered cholesterol oxidase containing noncovalently bound FAD.
Laura Caldinelli, Stefania Iametti, Alberto Barbiroli, Dimitrios Fessas, Francesco Bonomi

Protein Sci· March 2008

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Engineering the properties of D-amino acid oxidases by a rational and a directed evolution approach.
Loredano Pollegioni, Silvia Sacchi, Laura Caldinelli, Angelo Boselli, Mirella S Pilone

Curr Protein Pept Sci· December 2007

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Tryptophan 243 affects interprotein contacts, cofactor binding and stability in D-amino acid oxidase from Rhodotorula gracilis.
Laura Caldinelli, Gianluca Molla, Mirella S Pilone, Loredano Pollegioni

FEBS J· February 2006

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Dissecting the structural determinants of the stability of cholesterol oxidase containing covalently bound flavin.
Laura Caldinelli, Stefania Iametti, Alberto Barbiroli, Francesco Bonomi, Dimitrios Fessas

J Biol Chem· June 2005

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