Publications by authors named "Laura Corson"

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Clinical Targeted Next-Generation Panel Sequencing Reveals Amplification Is a Poor Prognostic Factor in Osteosarcoma.
Amanda E Marinoff, Liam F Spurr, Christina Fong, Yvonne Y Li, Suzanne J Forrest, Laura Corson

JCO Precis Oncol· March 2023

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CIViCdb 2022: evolution of an open-access cancer variant interpretation knowledgebase.
Kilannin Krysiak, Arpad M Danos, Jason Saliba, Joshua F McMichael, Adam C Coffman, Laura B Corson

Nucleic Acids Res· January 2023

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Molecular profiling identifies targeted therapy opportunities in pediatric solid cancer.
Alanna J Church, Laura B Corson, Pei-Chi Kao, Alma Imamovic-Tuco, Deirdre Reidy

Nat Med· August 2022

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Germline Sequencing Improves Tumor-Only Sequencing Interpretation in a Precision Genomic Study of Patients With Pediatric Solid Tumor.
Jaclyn Schienda, Alanna J Church, Laura B Corson, Brennan Decker, Catherine M Clinton

JCO Precis Oncol· March 2022

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Structure-based optimization of hydroxylactam as potent, cell-active inhibitors of lactate dehydrogenase.
BinQing Wei, Kirk Robarge, Sharada S Labadie, Jinhua Chen, Laura B Corson

Bioorg Med Chem Lett· March 2022

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Author Correction: Evasion of immunosurveillance by genomic alterations of PPARγ/RXRα in bladder cancer.
Manav Korpal, Xiaoling Puyang, Zhenhua Jeremy Wu, Roland Seiler, Craig Furman, Laura Corson

Nat Commun· June 2019

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Ushering in the next generation of precision trials for pediatric cancer.
Steven G DuBois, Laura B Corson, Kimberly Stegmaier, Katherine A Janeway

Science· March 2019

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Sensitivity to splicing modulation of BCL2 family genes defines cancer therapeutic strategies for splicing modulators.
Daniel Aird, Teng Teng, Chia-Ling Huang, Ermira Pazolli, Deepti Banka, Laura Corson

Nat Commun· January 2019

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Evasion of immunosurveillance by genomic alterations of PPARγ/RXRα in bladder cancer.
Manav Korpal, Xiaoling Puyang, Zhenhua Jeremy Wu, Roland Seiler, Craig Furman, Laura Corson

Nat Commun· July 2017

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Splicing modulators act at the branch point adenosine binding pocket defined by the PHF5A-SF3b complex.
Teng Teng, Jennifer Hc Tsai, Xiaoling Puyang, Michael Seiler, Shouyong Peng, Laura Corson

Nat Commun· May 2017

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Metabolic plasticity underpins innate and acquired resistance to LDHA inhibition.
Aaron Boudreau, Hans E Purkey, Anna Hitz, Kirk Robarge, David Peterson, Laura Corson

Nat Chem Biol· October 2016

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Cell Active Hydroxylactam Inhibitors of Human Lactate Dehydrogenase with Oral Bioavailability in Mice.
Hans E Purkey, Kirk Robarge, Jinhua Chen, Zhongguo Chen, Laura B Corson

ACS Med Chem Lett· October 2016

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Cancer-Associated SF3B1 Hotspot Mutations Induce Cryptic 3' Splice Site Selection through Use of a Different Branch Point.
Rachel B Darman, Michael Seiler, Anant A Agrawal, Kian H Lim, Shouyong Peng, Laura Corson

Cell Rep· November 2015

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Metabolite profiling stratifies pancreatic ductal adenocarcinomas into subtypes with distinct sensitivities to metabolic inhibitors.
Anneleen Daemen, David Peterson, Nisebita Sahu, Ron McCord, Xiangnan Du, Laura Corson

Proc Natl Acad Sci U S A· August 2015

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Optimization of 5-(2,6-dichlorophenyl)-3-hydroxy-2-mercaptocyclohex-2-enones as potent inhibitors of human lactate dehydrogenase.
Sharada Labadie, Peter S Dragovich, Jinhua Chen, Benjamin P Fauber, Jason Boggs, Laura B Corson

Bioorg Med Chem Lett· January 2015

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Identification of 3,6-disubstituted dihydropyrones as inhibitors of human lactate dehydrogenase.
Benjamin P Fauber, Peter S Dragovich, Jinhua Chen, Laura B Corson, Charles Z Ding

Bioorg Med Chem Lett· December 2014

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Total synthesis of 6-deoxypladienolide D and Assessment of Splicing Inhibitory Activity in a Mutant SF3B1 cancer cell line.
Kenzo Arai, Silvia Buonamici, Betty Chan, Laura Corson, Atsushi Endo

Org Lett· November 2014

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Identification of substituted 3-hydroxy-2-mercaptocyclohex-2-enones as potent inhibitors of human lactate dehydrogenase.
Peter S Dragovich, Benjamin P Fauber, Jason Boggs, Jinhua Chen, Laura B Corson

Bioorg Med Chem Lett· August 2014

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Identification of 2-amino-5-aryl-pyrazines as inhibitors of human lactate dehydrogenase.
Benjamin P Fauber, Peter S Dragovich, Jinhua Chen, Laura B Corson, Charles Z Ding

Bioorg Med Chem Lett· October 2013

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Identification of substituted 2-thio-6-oxo-1,6-dihydropyrimidines as inhibitors of human lactate dehydrogenase.
Peter S Dragovich, Benjamin P Fauber, Laura B Corson, Charles Z Ding, Charles Eigenbrot

Bioorg Med Chem Lett· June 2013

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A high-content cellular senescence screen identifies candidate tumor suppressors, including EPHA3.
Jenni Lahtela, Laura B Corson, Annabrita Hemmes, Matthew J Brauer, Sonja Koopal

Cell Cycle· February 2013

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An integrated genomic screen identifies LDHB as an essential gene for triple-negative breast cancer.
Mark L McCleland, Adam S Adler, Yonglei Shang, Thomas Hunsaker, Tom Truong, Laura Corson

Cancer Res· November 2012

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A class of 2,4-bisanilinopyrimidine Aurora A inhibitors with unusually high selectivity against Aurora B.
Ignacio Aliagas-Martin, Dan Burdick, Laura Corson, Jennafer Dotson, Jason Drummond

J Med Chem· May 2009

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A pentacyclic aurora kinase inhibitor (AKI-001) with high in vivo potency and oral bioavailability.
Thomas E Rawson, Matthias Rüth, Elizabeth Blackwood, Dan Burdick, Laura Corson

J Med Chem· August 2008

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Characterization of mouse Rsk4 as an inhibitor of fibroblast growth factor-RAS-extracellular signal-regulated kinase signaling.
Andrea Pomrehn Myers, Laura B Corson, Janet Rossant, Julie C Baker

Mol Cell Biol· May 2004

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