Publications by authors named "Laura Eccles"

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Treatment-Free Survival Over 6 Years of Follow-up in Patients With Metastatic NSCLC Treated With First-Line Nivolumab Plus Ipilimumab Versus Chemotherapy in CheckMate 227 Part 1.
Solange Peters, Meredith M Regan, Luis G Paz-Ares, Martin Reck, Hossein Borghaei, Laura J Eccles

J Thorac Oncol· October 2025

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Five-year outcomes with first-line nivolumab plus ipilimumab with 2 cycles of chemotherapy versus 4 cycles of chemotherapy alone in patients with metastatic non-small cell lung cancer in the randomized CheckMate 9LA trial.
Martin Reck, Tudor-Eliade Ciuleanu, Michael Schenker, Stephanie Bordenave, Manuel Cobo, Laura J Eccles

Eur J Cancer· November 2024

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Systemic and Intracranial Outcomes With First-Line Nivolumab Plus Ipilimumab in Patients With Metastatic NSCLC and Baseline Brain Metastases From CheckMate 227 Part 1.
Martin Reck, Tudor-Eliade Ciuleanu, Jong-Seok Lee, Michael Schenker, Bogdan Zurawski, Laura J Eccles

J Thorac Oncol· August 2023

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Treatment patterns and outcomes of patients with metastatic non-small cell lung cancer in five European countries: a real-world evidence survey.
Hollie Bailey, Adam Lee, Laura Eccles, Yong Yuan, Helen Burlison

BMC Cancer· June 2023

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Long-term comparative efficacy and safety of nivolumab plus ipilimumab relative to other first-line therapies for advanced non-small-cell lung cancer: A systematic literature review and network meta-analysis.
Kenneth O'Byrne, Evan Popoff, Firas Badin, Adam Lee, Yong Yuan, Laura J Eccles

Lung Cancer· March 2023

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Treatment patterns for advanced non-small cell lung cancer in the US: A systematic review of observational studies.
Adam Lee, Yong Yuan, Laura Eccles, Anushri Chitkara, Johan Dalén

Cancer Treat Res Commun· December 2022

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Correlations between objective response rate and survival-based endpoints in first-line advanced non-small cell lung Cancer: A systematic review and meta-analysis.
Sarah Goring, Nebibe Varol, Nathalie Waser, Evan Popoff, Greta Lozano-Ortega, Laura Eccles

Lung Cancer· August 2022

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Inhibition of non-homologous end joining in Fanconi Anemia cells results in rescue of survival after interstrand crosslinks but sensitization to replication associated double-strand breaks.
Laura J Eccles, Andrew C Bell, Simon N Powell

DNA Repair (Amst)· April 2018

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The EMSY threonine 207 phospho-site is required for EMSYdriven suppression of DNA damage repair.
Petar Jelinic, Laura A Eccles, Jill Tseng, Paulina Cybulska, Monicka Wielgos

Oncotarget· February 2017

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Efficient cleavage of single and clustered AP site lesions within mono-nucleosome templates by CHO-K1 nuclear extract contrasts with retardation of incision by purified APE1.
Laura J Eccles, Hervé Menoni, Dimitar Angelov, Martine E Lomax, Peter O'Neill

DNA Repair (Amst)· November 2015

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Delayed repair of radiation induced clustered DNA damage: friend or foe?
Laura J Eccles, Peter O'Neill, Martine E Lomax

Mutat Res· June 2011

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Hierarchy of lesion processing governs the repair, double-strand break formation and mutability of three-lesion clustered DNA damage.
Laura J Eccles, Martine E Lomax, Peter O'Neill

Nucleic Acids Res· March 2010

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