Publications by authors named "Laura Frame"

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Humanization of Drug Metabolism in the Mouse Model for Antimalarial Drug Discovery.
A Kenneth MacLeod, Cristina Merino, Sara Viera-Morilla, Laura Frame, Amy Tavendale

ACS Infect Dis· December 2025

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Application of a mouse model humanized for cytochrome P450-mediated drug metabolism to predict drug-drug interactions between a peptide and small molecule drugs.
Yury Kapelyukh, Charlotte Gabel-Jensen, Alastaire Kenneth MacLeod, Kevin-Sebastien Daniel Coquelin, Laste Stojanovski, Laura Frame

Drug Metab Dispos· October 2025

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Antitrypanosomal quinazolines targeting lysyl-tRNA synthetase show partial efficacy in a mouse model of acute Chagas disease.
Lindsay B Tulloch, Hugh Tawell, Annie E Taylor, Marta Lopes Lima, Alice Dawson, Laura Frame

Sci Transl Med· July 2025

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Structure-activity relationships of 1,5-dihydro-2-benzo[][1,4]diazepine-2,4(3)-diones as inhibitors of .
Michael G Thomas, Joanne Dunne, Peter G Dodd, Emiliana D'Oria, Laura Frame

RSC Med Chem· June 2025

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Use of an extensively humanized mouse model to predict the risk of drug-drug interactions in patients receiving dexamethasone.
Jacob George, James D Chalmers, Kevin-Sebastien Coquelin, Laura Frame, Colin J Henderson

J Pharmacol Exp Ther· February 2025

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lysyl-tRNA synthetase inhibitors define the interplay between solubility and permeability required to achieve efficacy.
Nicola Caldwell, Caroline Peet, Peter Miller, Beatrice L Colon, Malcolm G Taylor, Laura Frame

Sci Transl Med· October 2024

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Acceleration of infectious disease drug discovery and development using a humanized model of drug metabolism.
A Kenneth MacLeod, Kevin-Sebastien Coquelin, Leticia Huertas, Frederick R C Simeons, Jennifer Riley, Laura Frame

Proc Natl Acad Sci U S A· February 2024

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Integrating Treatment for Maternal Depression and Young Children's Behavior Problems.
Danielle Roubinov, Barbara Ivins, Laura Frame, Stephanie Simms, Linda Pfiffner

J Psychiatr Brain Sci· December 2023

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Structure-Guided Design and Synthesis of a Pyridazinone Series of Proteasome Inhibitors.
Michael G Thomas, Kate McGonagle, Paul Rowland, David A Robinson, Peter G Dodd, Laura Frame

J Med Chem· August 2023

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A Caregiver-Child Intervention for Mitigating Toxic Stress ("The Resiliency Clinic"): A Pilot Study.
Joan Jeung, Danielle Hessler Jones, Laura Frame, Rachel Gilgoff, Dayna Long

Matern Child Health J· October 2022

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Development of a label-free Raman imaging technique for differentiation of malaria parasite infected from non-infected tissue.
Laura Frame, James Brewer, Rebecca Lee, Karen Faulds, Duncan Graham

Analyst· December 2017

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Marriage education for clinicians.
Scott Wetzler, Laura Frame, Samantha Litzinger

Am J Psychother· March 2012

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Reasonable efforts? Implementation of the reunification bypass provision of ASFA.
Jill Duerr Berrick, Young Choi, Amy D'Andrade, Laura Frame

Child Welfare· March 2009

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Larval feeding duration affects ecdysteroid levels and nutritional reserves regulating pupal commitment in the yellow fever mosquito Aedes aegypti (Diptera: Culicidae).
Aparna Telang, Laura Frame, Mark R Brown

J Exp Biol· March 2007

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