Publications by authors named "Laura Hack"

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A stratified precision medicine trial targeting α-adrenergic receptor agonism as a treatment for the cognitive biotype of depression.
Laura M Hack, Jenna Jubeir, Rachel Hilton, Leonardo Tozzi, Leyla Boyar

Nat Ment Health· October 2025

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Opioids diminish the placebo antidepressant response: Observational post hoc findings from a randomized controlled ketamine trial.
Theresa R Lii, Josephine R Flohr, Robin L Okada, Lisa J Cianfichi, Laura M Hack

J Affect Disord· July 2025

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Conserved brain-wide emergence of emotional response from sensory experience in humans and mice.
Isaac Kauvar, Ethan B Richman, Tony X Liu, Chelsea Li, Sam Vesuna, Laura Hack

Science· May 2025

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Negative Affect Circuit Subtypes and Neural, Behavioral, and Affective Responses to MDMA: A Randomized Clinical Trial.
Xue Zhang, Laura M Hack, Claire Bertrand, Rachel Hilton, Nancy J Gray

JAMA Netw Open· April 2025

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Advancing precision psychiatry and targeted treatments: Insights from immunopsychiatry.
Andrew H Miller, Michael Berk, Gilles Bloch, Veronique Briquet-Laugier, Carinne Brouillon, Laura M Hack

Brain Behav Immun· March 2025

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A Stratified Precision Medicine Trial Targeting Selective Mechanisms of Alpha 2A Agonism as a Treatment for the Cognitive Biotype of Depression: The BIomarker Guided (BIG) Study for Depression.
Leanne Williams, Laura Hack, Jenna Jubeir, Rachel Hilton, Leonardo Tozzi

Res Sq· February 2025

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Opioids Diminish the Placebo Antidepressant Response: A Post Hoc Analysis of a Randomized Controlled Ketamine Trial.
Theresa R Lii, Josephine R Flohr, Robin L Okada, Lisa J Cianfichi, Laura M Hack

medRxiv· November 2024

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A cognitive neural circuit biotype of depression showing functional and behavioral improvement after transcranial magnetic stimulation in the B-SMART-fMRI trial.
Leonardo Tozzi, Claire Bertrand, Laura Michele Hack, Timothy Lyons, Alisa Marie Olmsted

Nat Ment Health· August 2024

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Prevalence and characteristics of preoperative patients with depression.
Tuuli M Hietamies, Ashleigh E Smith, Theresa R Lii, Evan Muzzall, Josephine Flohr, Laura M Hack

Br J Anaesth· July 2024

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Personalized brain circuit scores identify clinically distinct biotypes in depression and anxiety.
Leonardo Tozzi, Xue Zhang, Adam Pines, Alisa M Olmsted, Emily S Zhai, Laura M Hack

Nat Med· July 2024

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Reduction in Trauma-Related Symptoms After Anesthetic-Induced Intra-Operative Dreaming.
Laura M Hack, Pilleriin Sikka, Kelly Zhou, Makoto Kawai, Harrison S Chow

Am J Psychiatry· June 2024

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Randomized trial of ketamine masked by surgical anesthesia in patients with depression.
Theresa R Lii, Ashleigh E Smith, Josephine R Flohr, Robin L Okada, Cynthia A Nyongesa, Laura M Hack

Nat Ment Health· November 2023

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Ketamine's acute effects on negative brain states are mediated through distinct altered states of consciousness in humans.
Laura M Hack, Xue Zhang, Boris D Heifets, Trisha Suppes, Peter J van Roessel

Nat Commun· October 2023

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Randomized Trial of Ketamine Masked by Surgical Anesthesia in Depressed Patients.
Theresa R Lii, Ashleigh E Smith, Josephine R Flohr, Robin L Okada, Cynthia A Nyongesa, Laura M Hack

medRxiv· June 2023

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A Cognitive Biotype of Depression and Symptoms, Behavior Measures, Neural Circuits, and Differential Treatment Outcomes: A Prespecified Secondary Analysis of a Randomized Clinical Trial.
Laura M Hack, Leonardo Tozzi, Samantha Zenteno, Alisa M Olmsted, Rachel Hilton

JAMA Netw Open· June 2023

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Anesthetic-Induced Intraoperative Dream Associated With Remission of a Psychiatric Disorder: A Case Report.
Harrison S Chow, Laura M Hack, Makoto Kawai, Boris D Heifets

A A Pract· August 2022

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Exploring Nonmotor Neuropsychiatric Manifestations of Parkinson Disease in a Comprehensive Care Setting.
Amitha Dhingra, A Umair Janjua, Laura Hack, Gabriella Waserstein, Justin Palanci

J Geriatr Psychiatry Neurol· May 2021

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Epigenetic prediction of 17β-estradiol and relationship to trauma-related outcomes in women.
Laura M Hack, Shota Nishitani, Anna K Knight, Varun Kilaru, Stephanie A Maddox

Compr Psychoneuroendocrinol· May 2021

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Intrinsic reward circuit connectivity profiles underlying symptom and quality of life outcomes following antidepressant medication: a report from the iSPOT-D trial.
Adina S Fischer, Bailey Holt-Gosselin, Scott L Fleming, Laura M Hack, Tali M Ball

Neuropsychopharmacology· March 2021

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Shared genetic risk between eating disorder- and substance-use-related phenotypes: Evidence from genome-wide association studies.
Melissa A Munn-Chernoff, Emma C Johnson, Yi-Ling Chou, Jonathan R I Coleman, Laura M Thornton, Laura M Hack

Addict Biol· January 2021

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A large-scale genome-wide association study meta-analysis of cannabis use disorder.
Emma C Johnson, Ditte Demontis, Thorgeir E Thorgeirsson, Raymond K Walters, Renato Polimanti, Laura M Hack

Lancet Psychiatry· December 2020

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Leveraging genome-wide data to investigate differences between opioid use vs. opioid dependence in 41,176 individuals from the Psychiatric Genomics Consortium.
Renato Polimanti, Raymond K Walters, Emma C Johnson, Jeanette N McClintick, Amy E Adkins, Laura M Hack

Mol Psychiatry· August 2020

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A precision medicine-based, 'fast-fail' approach for psychiatry.
Leanne M Williams, Laura M Hack

Nat Med· May 2020

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Moving pharmacoepigenetics tools for depression toward clinical use.
Laura M Hack, Gabriel R Fries, Harris A Eyre, Chad A Bousman, Ajeet B Singh

J Affect Disord· April 2019

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