Publications by authors named "Laura Hedges"

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Metabolism of bifenthrin, β-cyfluthrin, λ-cyhalothrin, cyphenothrin and esfenvalerate by rat and human cytochrome P450 and carboxylesterase enzymes.
Laura Hedges, Susan Brown, A Kenneth MacLeod, Marjory Moreau, Miyoung Yoon

Xenobiotica· December 2020

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The efficacy of a topical formulation of selamectin plus sarolaner in preventing the development of a macrocyclic lactone-resistant strain of Dirofilaria immitis in cats.
Aleah Pullins, Tom L McTier, Sean Mahabir, Guy DeRose, Laura Hedges

Vet Parasitol· June 2020

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Metabolism of deltamethrin and cis- and trans-permethrin by human expressed cytochrome P450 and carboxylesterase enzymes.
Laura Hedges, Susan Brown, A Kenneth MacLeod, Audrey Vardy, Edward Doyle

Xenobiotica· May 2019

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Metabolism of deltamethrin and cis- and trans-permethrin by rat and human liver microsomes, liver cytosol and plasma preparations.
Laura Hedges, Susan Brown, Audrey Vardy, Edward Doyle, Miyoung Yoon

Xenobiotica· April 2019

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Determination of the effective dose of a novel oral formulation of sarolaner (Simparica™) for the treatment and month-long control of fleas and ticks on dogs.
Tom L McTier, Robert H Six, Josephus J Fourie, Aleah Pullins, Laura Hedges

Vet Parasitol· May 2016

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Discovery of sarolaner: A novel, orally administered, broad-spectrum, isoxazoline ectoparasiticide for dogs.
Tom L McTier, Nathan Chubb, Michael P Curtis, Laura Hedges, Gregory A Inskeep

Vet Parasitol· May 2016

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Design and synthesis of sarolaner, a novel, once-a-month, oral isoxazoline for the control of fleas and ticks on dogs.
Michael P Curtis, Valerie Vaillancourt, Richard M Goodwin, Nathan A L Chubb, William Howson, Laura Hedges

Bioorg Med Chem Lett· April 2016

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Pharmacokinetic interaction of the antiparasitic agents ivermectin and spinosad in dogs.
Stewart T Dunn, Laura Hedges, Kathleen E Sampson, Yurong Lai, Sean Mahabir

Drug Metab Dispos· May 2011

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