Publications by authors named "Laura Ielo"

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Syntheses, reactivity, and biological applications of coumarins.
Andrea Citarella, Serena Vittorio, Christian Dank, Laura Ielo

Front Chem· February 2024

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Continuous Synthesis of Carbamates from CO and Amines.
Kristof Stagel, Laura Ielo, Katharina Bica-Schröder

ACS Omega· December 2023

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Selective noncovalent proteasome inhibiting activity of trifluoromethyl-containing gem-quaternary aziridines.
Laura Ielo, Vincenzo Patamia, Andrea Citarella, Tanja Schirmeister, Claudio Stagno

Arch Pharm (Weinheim)· July 2023

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Recent advances in the accessibility, synthetic utility, and biological applications of aziridines.
Christian Dank, Laura Ielo

Org Biomol Chem· June 2023

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Heterocyclic Compounds as Synthetic Tyrosinase Inhibitors: Recent Advances.
Serena Vittorio, Christian Dank, Laura Ielo

Int J Mol Sci· May 2023

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Leveraging the 3-Chloro-4-fluorophenyl Motif to Identify Inhibitors of Tyrosinase from .
Salvatore Mirabile, Laura Ielo, Lisa Lombardo, Federico Ricci, Rosaria Gitto

Int J Mol Sci· April 2023

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Synthesis, computational investigation and biological evaluation of α,α-difluoromethyl ketones embodying pyrazole and isoxazole nuclei as COX inhibitors.
Andrea Citarella, Laura Ielo, Claudio Stagno, Mariateresa Cristani, Claudia Muscarà

Org Biomol Chem· November 2022

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Novel Class of Proteasome Inhibitors: In Silico and In Vitro Evaluation of Diverse Chloro(trifluoromethyl)aziridines.
Laura Ielo, Vincenzo Patamia, Andrea Citarella, Thomas Efferth, Nasim Shahhamzehei

Int J Mol Sci· October 2022

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Evaluation of 4-(4-Fluorobenzyl)piperazin-1-yl]-Based Compounds as Competitive Tyrosinase Inhibitors Endowed with Antimelanogenic Effects.
Salvatore Mirabile, Serena Vittorio, Maria Paola Germanò, Ilenia Adornato, Laura Ielo

ChemMedChem· October 2021

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Taking advantage of lithium monohalocarbenoid intrinsic α-elimination in 2-MeTHF: controlled epoxide ring-opening to halohydrins.
Laura Ielo, Margherita Miele, Veronica Pillari, Raffaele Senatore, Salvatore Mirabile

Org Biomol Chem· March 2021

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Direct and straightforward transfer of C1 functionalized synthons to phosphorous electrophiles for accessing gem-P-containing methanes.
Saad Touqeer, Laura Ielo, Margherita Miele, Ernst Urban, Wolfgang Holzer

Org Biomol Chem· March 2021

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Electrophilicity Scale of Activated Amides: O NMR and N NMR Chemical Shifts of Acyclic Twisted Amides in N-C(O) Cross-Coupling.
Laura Ielo, Vittorio Pace, Wolfgang Holzer, Md Mahbubur Rahman, Guangrong Meng

Chemistry· December 2020

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Halogen-Imparted Reactivity in Lithium Carbenoid Mediated Homologations of Imine Surrogates: Direct Assembly of bis-Trifluoromethyl-β-Diketiminates and the Dual Role of LiCHI.
Laura Ielo, Laura Castoldi, Saad Touqeer, Jessica Lombino, Alexander Roller

Angew Chem Int Ed Engl· November 2020

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Chemoselective Homologation-Deoxygenation Strategy Enabling the Direct Conversion of Carbonyls into ()-Halomethyl-Alkanes.
Margherita Miele, Andrea Citarella, Thierry Langer, Ernst Urban, Martin Zehl, Laura Ielo

Org Lett· October 2020

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Straightforward chemoselective access to unsymmetrical dithioacetals through a thiosulfonate homologation-nucleophilic substitution sequence.
Laura Ielo, Veronica Pillari, Natalie Gajic, Wolfgang Holzer, Vittorio Pace

Chem Commun (Camb)· October 2020

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4-Fluorobenzylpiperazine-Containing Derivatives as Efficient Inhibitors of Mushroom Tyrosinase.
Serena Vittorio, Laura Ielo, Salvatore Mirabile, Rosaria Gitto, Antonella Fais

ChemMedChem· September 2020

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Inhibition of HIV-1 RT activity by a new series of 3-(1,3,4-thiadiazol-2-yl)thiazolidin-4-one derivatives.
Maria Rosa Buemi, Rosaria Gitto, Laura Ielo, Christophe Pannecouque, Laura De Luca

Bioorg Med Chem· April 2020

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A Combination of Pharmacophore and Docking-based Virtual Screening to Discover new Tyrosinase Inhibitors.
Serena Vittorio, Thomas Seidel, Maria Paola Germanò, Rosaria Gitto, Laura Ielo

Mol Inform· March 2020

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Exploiting the 1-(4-fluorobenzyl)piperazine fragment for the development of novel tyrosinase inhibitors as anti-melanogenic agents: Design, synthesis, structural insights and biological profile.
Laura Ielo, Batel Deri, Maria Paola Germanò, Serena Vittorio, Salvatore Mirabile

Eur J Med Chem· September 2019

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Direct Access to 9-Chloro-1-benzo[]furo[3,4-]azepin-1-ones via Palladium(II)-Catalyzed Intramolecular -Oxypalladation/Olefin Insertion/sp-C-H Bond Activation Cascade.
Muthu Karuppasamy, B S Vachan, Perumal Vinoth, Isravel Muthukrishnan, Subbiah Nagarajan, Laura Ielo

Org Lett· August 2019

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O NMR and N NMR chemical shifts of sterically-hindered amides: ground-state destabilization in amide electrophilicity.
Vittorio Pace, Wolfgang Holzer, Laura Ielo, Shicheng Shi, Guangrong Meng

Chem Commun (Camb)· April 2019

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Telescoped, Divergent, Chemoselective C1 and C1-C1 Homologation of Imine Surrogates: Access to Quaternary Chloro- and Halomethyl-Trifluoromethyl Aziridines.
Laura Ielo, Saad Touqeer, Alexander Roller, Thierry Langer, Wolfgang Holzer

Angew Chem Int Ed Engl· February 2019

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Correction to Targeting Tyrosinase: Development and Structural Insights of Novel Inhibitors Bearing Arylpiperidine and Arylpiperazine Fragments.
Stefania Ferro, Batel Deri, Maria Paola Germanò, Rosaria Gitto, Laura Ielo

J Med Chem· February 2019

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Homologation chemistry with nucleophilic α-substituted organometallic reagents: chemocontrol, new concepts and (solved) challenges.
Laura Castoldi, Serena Monticelli, Raffaele Senatore, Laura Ielo, Vittorio Pace

Chem Commun (Camb)· June 2018

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Expeditious and Chemoselective Synthesis of α-Aryl and α-Alkyl Selenomethylketones via Homologation Chemistry.
Raffaele Senatore, Laura Castoldi, Laura Ielo, Wolfgang Holzer, Vittorio Pace

Org Lett· May 2018

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