Publications by authors named "Laura Lancaster"

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The ribosome derives the energy to translocate and unwind mRNA from EF-G binding.
Hossein Amiri, William J Van Patten, Gillian Rexroad, Varsha P Desai, Benjamen A Sterwerf, Laura Lancaster

Nat Commun· December 2025

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Implication of nucleotides near the 3' end of 16S rRNA in guarding the translational reading frame.
Alexandria Smart, Laura Lancaster, John Paul Donohue, Dustin Niblett, Harry F Noller

Nucleic Acids Res· June 2024

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The role of GTP hydrolysis by EF-G in ribosomal translocation.
Gillian Rexroad, John Paul Donohue, Laura Lancaster, Harry F Noller

Proc Natl Acad Sci U S A· November 2022

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Mutations in domain IV of elongation factor EF-G confer -1 frameshifting.
Dustin Niblett, Charlotte Nelson, Calvin S Leung, Gillian Rexroad, Jake Cozy, Laura Lancaster

RNA· January 2021

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The structural basis for inhibition of ribosomal translocation by viomycin.
Ling Zhang, Ying-Hui Wang, Xing Zhang, Laura Lancaster, Jie Zhou

Proc Natl Acad Sci U S A· May 2020

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Co-temporal Force and Fluorescence Measurements Reveal a Ribosomal Gear Shift Mechanism of Translation Regulation by Structured mRNAs.
Varsha P Desai, Filipp Frank, Antony Lee, Maurizio Righini, Laura Lancaster

Mol Cell· September 2019

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Spontaneous ribosomal translocation of mRNA and tRNAs into a chimeric hybrid state.
Jie Zhou, Laura Lancaster, John Paul Donohue, Harry F Noller

Proc Natl Acad Sci U S A· April 2019

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The ribosome moves: RNA mechanics and translocation.
Harry F Noller, Laura Lancaster, Jie Zhou, Srividya Mohan

Nat Struct Mol Biol· December 2017

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Ribosome structural dynamics in translocation: yet another functional role for ribosomal RNA.
Harry F Noller, Laura Lancaster, Srividya Mohan, Jie Zhou

Q Rev Biophys· January 2017

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How the ribosome hands the A-site tRNA to the P site during EF-G-catalyzed translocation.
Jie Zhou, Laura Lancaster, John Paul Donohue, Harry F Noller

Science· September 2014

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Direct measurement of the mechanical work during translocation by the ribosome.
Tingting Liu, Ariel Kaplan, Lisa Alexander, Shannon Yan, Jin-Der Wen, Laura Lancaster

Elife· August 2014

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Visualization of two transfer RNAs trapped in transit during elongation factor G-mediated translocation.
David J F Ramrath, Laura Lancaster, Thiemo Sprink, Thorsten Mielke, Justus Loerke

Proc Natl Acad Sci U S A· December 2013

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Crystal structures of EF-G-ribosome complexes trapped in intermediate states of translocation.
Jie Zhou, Laura Lancaster, John Paul Donohue, Harry F Noller

Science· June 2013

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Crystal structures of 70S ribosomes bound to release factors RF1, RF2 and RF3.
Jie Zhou, Andrei Korostelev, Laura Lancaster, Harry F Noller

Curr Opin Struct Biol· December 2012

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Ribosomal protein S1 unwinds double-stranded RNA in multiple steps.
Xiaohui Qu, Laura Lancaster, Harry F Noller, Carlos Bustamante, Ignacio Tinoco

Proc Natl Acad Sci U S A· September 2012

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Crystal structure of release factor RF3 trapped in the GTP state on a rotated conformation of the ribosome.
Jie Zhou, Laura Lancaster, Sergei Trakhanov, Harry F Noller

RNA· February 2012

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The ribosome uses two active mechanisms to unwind messenger RNA during translation.
Xiaohui Qu, Jin-Der Wen, Laura Lancaster, Harry F Noller, Carlos Bustamante

Nature· July 2011

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Fluorescently labeled ribosomes as a tool for analyzing antibiotic binding.
Beatriz Llano-Sotelo, Robyn P Hickerson, Laura Lancaster, Harry F Noller, Alexander S Mankin

RNA· August 2009

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Crystal structure of a translation termination complex formed with release factor RF2.
Andrei Korostelev, Haruichi Asahara, Laura Lancaster, Martin Laurberg, Alexander Hirschi

Proc Natl Acad Sci U S A· December 2008

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The sarcin-ricin loop of 23S rRNA is essential for assembly of the functional core of the 50S ribosomal subunit.
Laura Lancaster, Nicole J Lambert, Eric J Maklan, Lucas H Horan, Harry F Noller

RNA· October 2008

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Following translation by single ribosomes one codon at a time.
Jin-Der Wen, Laura Lancaster, Courtney Hodges, Ana-Carolina Zeri, Shige H Yoshimura

Nature· April 2008

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Interactions and dynamics of the Shine Dalgarno helix in the 70S ribosome.
Andrei Korostelev, Sergei Trakhanov, Haruichi Asahara, Martin Laurberg, Laura Lancaster

Proc Natl Acad Sci U S A· October 2007

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Deletion of a conserved, central ribosomal intersubunit RNA bridge.
Iraj K Ali, Laura Lancaster, Jason Feinberg, Simpson Joseph, Harry F Noller

Mol Cell· September 2006

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Involvement of 16S rRNA nucleotides G1338 and A1339 in discrimination of initiator tRNA.
Laura Lancaster, Harry F Noller

Mol Cell· November 2005

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Orientation of ribosome recycling factor in the ribosome from directed hydroxyl radical probing.
Laura Lancaster, Michael C Kiel, Akira Kaji, Harry F Noller

Cell· October 2002

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