Publications by authors named "Laura Lentini"

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CFTR rescue in W1282X cystic fibrosis patient-derived intestinal organoids (PDIOs) mediated by translational readthrough-inducing drugs (TRIDs).
Riccardo Perriera, Anabela S Ramalho, Francois Vermeulen, Emanuele Vitale, Ivana Pibiri, Laura Lentini

Genet Med Open· January 2026

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Alternative polyadenylation and splicing regulation in refractory juvenile dermatomyositis: CELF2 at the crossroads.
Riccardo Varrica, Laura Lentini

Mol Ther Nucleic Acids· December 2025

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Developing a National Network for Leukodystrophy Research and Care in Canada: The CARELeuko Initiative.
Alexandra Chapleau, Adam Le, Justin Simo, Sunita Venkateswaran, Thierry Lacaze-Masmonteil, Laura Lentini

Neurol Genet· December 2025

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Exploring innovative approaches in cancer immunotherapy by exploiting the role of translational readthrough-inducing drugs.
Laura Lentini, Andrea Pace

Mol Ther· December 2025

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Correcting CFTR mRNA splicing defects with the plant cytokine kinetin and its analogues.
Valeria Rimoldi, Giulia Soldà, Anita Capalbo, Elena Saba, Valentina Giannone, Laura Lentini

J Cyst Fibros· November 2025

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A precision medicine approach to primary immunodeficiency disease: Ataluren strikes nonsense mutations once again.
Laura Lentini, Riccardo Perriera, Federica Corrao, Raffaella Melfi, Marco Tutone

Mol Ther· July 2025

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Nonsense Mutations in Rare and Ultra-Rare Human Disorders: An Overview.
Emanuele Vitale, Davide Ricci, Federica Corrao, Ignazio Fiduccia, Ilenia Cruciata, Laura Lentini

IUBMB Life· June 2025

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Advancing Therapeutic Strategies for Nonsense-Related Diseases: From Small Molecules to Nucleic Acid-Based Innovations.
Davide Ricci, Ilenia Cruciata, Ignazio Fiduccia, Emanuele Vitale, Federica Corrao, Laura Lentini

IUBMB Life· May 2025

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Stress and Quality of Life of Parents of Children With POLR3-Related Leukodystrophy: A Cross-Sectional Pilot Study.
Laura Lentini, Helia Toutounchi, Alexandra Chapleau, Adam Le, Simon Fournier

J Child Neurol· January 2025

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Promoting readthrough of nonsense mutations in CF mouse model: Biodistribution and efficacy of NV848 in rescuing CFTR protein expression.
Ignazio Fiduccia, Federica Corrao, Maria Grazia Zizzo, Riccardo Perriera, Francesco Genovese, Laura Lentini

Mol Ther· December 2024

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Readthrough Approach Using NV Translational Readthrough-Inducing Drugs (TRIDs): A Study of the Possible Off-Target Effects on Natural Termination Codons (NTCs) on TP53 and Housekeeping Gene Expression.
Riccardo Perriera, Emanuele Vitale, Ivana Pibiri, Pietro Salvatore Carollo, Davide Ricci, Laura Lentini

Int J Mol Sci· October 2023

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Investigating the Inhibition of FTSJ1, a Tryptophan tRNA-Specific 2'-O-Methyltransferase by NV TRIDs, as a Mechanism of Readthrough in Nonsense Mutated CFTR.
Pietro Salvatore Carollo, Marco Tutone, Giulia Culletta, Ignazio Fiduccia, Federica Corrao, Laura Lentini

Int J Mol Sci· June 2023

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Nonsense codons suppression. An acute toxicity study of three optimized TRIDs in murine model, safety and tolerability evaluation.
Federica Corrao, Maria Grazia Zizzo, Marco Tutone, Raffaella Melfi, Ignazio Fiduccia, Laura Lentini

Biomed Pharmacother· December 2022

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Aging modifies receptor expression but not muscular contractile response to angiotensin II in rat jejunum.
Maria Grazia Zizzo, Adele Cicio, Federica Corrao, Laura Lentini, Rosa Serio

J Physiol Biochem· November 2022

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Novel Translational Read-through-Inducing Drugs as a Therapeutic Option for Shwachman-Diamond Syndrome.
Valentino Bezzerri, Laura Lentini, Martina Api, Elena Marinelli Busilacchi, Vincenzo Cavalieri

Biomedicines· April 2022

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Preventive Impact of Long-Term Ingestion of Chestnut Honey on Glucose Disorders and Neurodegeneration in Obese Mice.
Simona Terzo, Pasquale Calvi, Domenico Nuzzo, Pasquale Picone, Giacoma Galizzi, Laura Lentini

Nutrients· February 2022

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Targeting Nonsense: Optimization of 1,2,4-Oxadiazole TRIDs to Rescue CFTR Expression and Functionality in Cystic Fibrosis Cell Model Systems.
Ivana Pibiri, Raffaella Melfi, Marco Tutone, Aldo Di Leonardo, Andrea Pace, Laura Lentini

Int J Mol Sci· September 2020

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Investigating REPAIRv2 as a Tool to Edit mRNA with Premature Stop Codons.
Raffaella Melfi, Patrizia Cancemi, Roberta Chiavetta, Viviana Barra, Laura Lentini

Int J Mol Sci· July 2020

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TRPM8 Channel Activation Reduces the Spontaneous Contractions in Human Distal Colon.
Antonella Amato, Simona Terzo, Laura Lentini, Pierenrico Marchesa, Flavia Mulè

Int J Mol Sci· July 2020

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Glucagon-like peptide-2 analog and inflammatory state in obese mice.
Sara Baldassano, Antonella Amato, Simona Terzo, Gaetano Felice Caldara, Laura Lentini

Endocrine· June 2020

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Inhalable nano into micro dry powders for ivacaftor delivery: The role of mannitol and cysteamine as mucus-active agents.
Barbara Porsio, Laura Lentini, Francesca Ungaro, Aldo Di Leonardo, Fabiana Quaglia

Int J Pharm· May 2020

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Pharmacophore-Based Design of New Chemical Scaffolds as Translational Readthrough-Inducing Drugs (TRIDs).
Marco Tutone, Ivana Pibiri, Riccardo Perriera, Ambra Campofelice, Giulia Culletta, Laura Lentini

ACS Med Chem Lett· May 2020

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Strategies against Nonsense: Oxadiazoles as Translational Readthrough-Inducing Drugs (TRIDs).
Ambra Campofelice, Laura Lentini, Aldo Di Leonardo, Raffaella Melfi, Marco Tutone

Int J Mol Sci· July 2019

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Caffeine boosts Ataluren's readthrough activity.
Laura Lentini, Raffaella Melfi, Patrizia Cancemi, Ivana Pibiri, Aldo Di Leonardo

Heliyon· June 2019

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Deciphering the Nonsense Readthrough Mechanism of Action of Ataluren: An Compared Study.
Marco Tutone, Ivana Pibiri, Laura Lentini, Andrea Pace, Anna Maria Almerico

ACS Med Chem Lett· April 2019

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