Publications by authors named "Laura Leyva"

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Discovery and early validation of serum protein signatures in untreated multiple sclerosis patients: identification of candidate biomarkers for diagnosis and stratification.
Isabel Brichette-Mieg, Ana Alonso-Torres, Pablo Aliaga-Gaspar, José-Luis Rodríguez-Bada, Virginia Reyes-Garrido, Laura Leyva

Front Immunol· September 2025

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Bluefin tuna () larvae exploit rare food sources to break food limitations in their warm oligotrophic environment.
Patricia Reglero, Maria Pilar Tugores, Josefin Titelman, Mar Santandreu, Melissa Martin, Laura Leyva

J Plankton Res· March 2025

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Identification of the genetic mechanism that associates L3MBTL3 to multiple sclerosis.
Antonio Alcina, Maria Fedetz, Isabel Vidal-Cobo, Eduardo Andrés-León, Maria-Isabel García-Sánchez, Laura Leyva

Hum Mol Genet· July 2022

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Technical challenges for complete implementation of automated growth-based methods for microbiological examination of advanced therapy medicinal products. What's wrong with Candida albicans?
Antonio Rodríguez-Acosta, Jesús Chaparro-García, Inmaculada De-Toro, Rafael Maldonado-Sánchez, Raquel Muñoz-Fernández, Laura Leyva

Cytotherapy· March 2022

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Soluble Receptor Isoform of IFN-Beta (sIFNAR2) in Multiple Sclerosis Patients and Their Association With the Clinical Response to IFN-Beta Treatment.
Pablo Aliaga-Gaspar, Isaac Hurtado-Guerrero, Nicolas Lundahl Ciano-Petersen, Patricia Urbaneja, Isabel Brichette-Mieg, Laura Leyva

Front Immunol· February 2022

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Treatment of faecal incontinence with autologous expanded mesenchymal stem cells: results of a pilot study.
Fernando de la Portilla, José Luis Guerrero, Maria Victoria Maestre, Laura Leyva, Santiago Mera

Colorectal Dis· March 2021

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Activation of Macrophages by Lysophosphatidic Acid through the Lysophosphatidic Acid Receptor 1 as a Novel Mechanism in Multiple Sclerosis Pathogenesis.
Jennifer Fransson, Ana Isabel Gómez-Conde, Jesús Romero-Imbroda, Oscar Fernández, Laura Leyva

Mol Neurobiol· February 2021

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Skin Phototype Could Be a Risk Factor for Multiple Sclerosis.
Patricia Urbaneja, Isaac Hurtado-Guerrero, Miguel Ángel Hernández, Begoña Oliver-Martos, Celia Oreja-Guevara, Laura Leyva

J Clin Med· July 2020

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Antiviral, Immunomodulatory and Antiproliferative Activities of Recombinant Soluble IFNAR2 without IFN-ß Mediation.
Isaac Hurtado-Guerrero, Bruno Hernáez, María J Pinto-Medel, Esther Calonge, José L Rodriguez-Bada, Laura Leyva

J Clin Med· March 2020

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A New Risk Variant for Multiple Sclerosis at 11q23.3 Is Associated with Expansion of Circulating Regulatory T Cells.
Elia Gil-Varea, Maria Fedetz, Herena Eixarch, Nino Spataro, Luisa María Villar, Laura Leyva

J Clin Med· February 2020

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Mesenchymal Stem Cells From Adipose Tissue Do not Improve Functional Recovery After Ischemic Stroke in Hypertensive Rats.
Luke Diekhorst, Mari Carmen Gómez-de Frutos, Fernando Laso-García, Laura Otero-Ortega, Blanca Fuentes, Laura Leyva

Stroke· January 2020

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Exome sequencing in multiple sclerosis families identifies 12 candidate genes and nominates biological pathways for the genesis of disease.
Carles Vilariño-Güell, Alexander Zimprich, Filippo Martinelli-Boneschi, Bruno Herculano, Zhe Wang, Laura Leyva

PLoS Genet· June 2019

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Adipose-derived mesenchymal stem cells (AdMSC) for the treatment of secondary-progressive multiple sclerosis: A triple blinded, placebo controlled, randomized phase I/II safety and feasibility study.
Oscar Fernández, Guillermo Izquierdo, Victoria Fernández, Laura Leyva, Virginia Reyes

PLoS One· July 2018

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Cross-reactivity of antibodies against interferon beta in multiple sclerosis patients and interference of the JAK-STAT signaling pathway.
Isaac Hurtado-Guerrero, Maria Jesus Pinto-Medel, Patricia Urbaneja, Jose Luis Rodriguez-Bada, Jesús Ortega-Pinazo, Laura Leyva

Sci Rep· November 2017

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Activation of the JAK-STAT Signaling Pathway after In Vitro Stimulation with IFNß in Multiple Sclerosis Patients According to the Therapeutic Response to IFNß.
Isaac Hurtado-Guerrero, Maria Jesús Pinto-Medel, Patricia Urbaneja, Jose Luis Rodriguez-Bada, Antonio León, Laura Leyva

PLoS One· August 2017

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Global methylation correlates with clinical status in multiple sclerosis patients in the first year of IFNbeta treatment.
María Jesús Pinto-Medel, Begoña Oliver-Martos, Patricia Urbaneja-Romero, Isaac Hurtado-Guerrero, Jesús Ortega-Pinazo, Laura Leyva

Sci Rep· August 2017

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Decreased soluble IFN-β receptor (sIFNAR2) in multiple sclerosis patients: A potential serum diagnostic biomarker.
Teresa Órpez-Zafra, Jose Pavía, Isaac Hurtado-Guerrero, Maria J Pinto-Medel, Jose Luis Rodriguez Bada, Laura Leyva

Mult Scler· June 2017

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Development and validation of an ELISA for quantification of soluble IFN-β receptor: assessment in multiple sclerosis.
Teresa Órpez-Zafra, Jose Pavía, Maria J Pinto-Medel, Isaac Hurtado-Guerrero, Jose L Rodriguez-Bada, Laura Leyva

Bioanalysis· September 2016

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Analysis of Plasminogen Genetic Variants in Multiple Sclerosis Patients.
A Dessa Sadovnick, Anthony L Traboulsee, Cecily Q Bernales, Jay P Ross, Amanda L Forwell, Laura Leyva

G3 (Bethesda)· July 2016

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Cell-based product classification procedure: What can be done differently to improve decisions on borderline products?
Ander Izeta, Concha Herrera, Rosario Mata, Giuseppe Astori, Rosaria Giordano, Laura Leyva

Cytotherapy· July 2016

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TRAIL and TRAIL receptors splice variants during long-term interferon β treatment of patients with multiple sclerosis: evaluation as biomarkers for therapeutic response.
Carlos López-Gómez, Begoña Oliver-Martos, María-Jesús Pinto-Medel, Margarita Suardiaz, Virginia Reyes-Garrido, Laura Leyva

J Neurol Neurosurg Psychiatry· February 2016

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Genome-wide significant association with seven novel multiple sclerosis risk loci.
Christina M Lill, Felix Luessi, Antonio Alcina, Ekaterina A Sokolova, Nerea Ugidos, Laura Leyva

J Med Genet· December 2015

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A functional variant that affects exon-skipping and protein expression of SP140 as genetic mechanism predisposing to multiple sclerosis.
Fuencisla Matesanz, Victor Potenciano, Maria Fedetz, Priscila Ramos-Mozo, María del Mar Abad-Grau, Laura Leyva

Hum Mol Genet· October 2015

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Pharmacogenomic study in patients with multiple sclerosis: Responders and nonresponders to IFN-β.
Marta F Bustamante, Carlos Morcillo-Suárez, Sunny Malhotra, Jordi Rio, Laura Leyva

Neurol Neuroimmunol Neuroinflamm· October 2015

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Lipid-specific immunoglobulin M bands in cerebrospinal fluid are associated with a reduced risk of developing progressive multifocal leukoencephalopathy during treatment with natalizumab.
Luisa M Villar, Lucienne Costa-Frossard, Thomas Masterman, Oscar Fernandez, Xavier Montalban, Laura Leyva

Ann Neurol· March 2015

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