Publications by authors named "Laura Novik"

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Rational Design of Multiclade Coronavirus Spike Immunodominant Domain Nanoparticles to Elicit Broad Antibody Responses.
Christian K O Dzuvor, Sydney Moak, Lindsay R McManus, Abigail Thomas, Abigail E Dzordzorme, Laura Novik

bioRxiv· October 2025

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Virologic effects of broadly neutralizing antibodies VRC01LS and VRC07-523LS on chronic HIV-1 infection.
Myra Happe, Rebecca M Lynch, Carl J Fichtenbaum, Sonya L Heath, Susan L Koletar, Laura Novik

JCI Insight· February 2025

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Phase 1 dose-escalation trial evaluating a group 2 influenza hemagglutinin stabilized stem nanoparticle vaccine.
Joseph P Casazza, Amelia R Hofstetter, Pamela J M Costner, LaSonji A Holman, Cynthia S Hendel, Laura Novik

NPJ Vaccines· September 2024

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Heterologous cAd3-Ebola and MVA-EbolaZ vaccines are safe and immunogenic in US and Uganda phase 1/1b trials.
Myra Happe, Amelia R Hofstetter, Jing Wang, Galina V Yamshchikov, LaSonji A Holman, Laura Novik

NPJ Vaccines· March 2024

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HIV-1 neutralizing antibodies elicited in humans by a prefusion-stabilized envelope trimer form a reproducible class targeting fusion peptide.
Shuishu Wang, Flavio Matassoli, Baoshan Zhang, Tracy Liu, Chen-Hsiang Shen, Laura Novik

Cell Rep· July 2023

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Clinical outcomes and immune responses to SARS-CoV-2 vaccination in severe aplastic anaemia.
Roma V Rajput, Xiaoyang Ma, Kristin L Boswell, Martin Gaudinski, Ingelise Gordon, Laura Novik

Br J Haematol· December 2022

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Primary exposure to SARS-CoV-2 variants elicits convergent epitope specificities, immunoglobulin V gene usage and public B cell clones.
Noemia S Lima, Maryam Musayev, Timothy S Johnston, Danielle A Wagner, Amy R Henry, Laura Novik

Nat Commun· December 2022

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Primary exposure to SARS-CoV-2 variants elicits convergent epitope specificities, immunoglobulin V gene usage and public B cell clones.
Noemia S Lima, Maryam Musayev, Timothy S Johnston, Danielle A Wagner, Amy R Henry, Laura Novik

bioRxiv· June 2022

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Safety and immunogenicity of an HIV-1 prefusion-stabilized envelope trimer (Trimer 4571) vaccine in healthy adults: A first-in-human open-label, randomized, dose-escalation, phase 1 clinical trial.
Katherine V Houser, Martin R Gaudinski, Myra Happe, Sandeep Narpala, Raffaello Verardi, Laura Novik

EClinicalMedicine· June 2022

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Safety and tolerability of AAV8 delivery of a broadly neutralizing antibody in adults living with HIV: a phase 1, dose-escalation trial.
Joseph P Casazza, Evan M Cale, Sandeep Narpala, Galina V Yamshchikov, Emily E Coates, Laura Novik

Nat Med· May 2022

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Durability of mRNA-1273 vaccine-induced antibodies against SARS-CoV-2 variants.
Amarendra Pegu, Sarah E O'Connell, Stephen D Schmidt, Sijy O'Dell, Chloe A Talana, Laura Novik

Science· September 2021

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Ultrapotent antibodies against diverse and highly transmissible SARS-CoV-2 variants.
Lingshu Wang, Tongqing Zhou, Yi Zhang, Eun Sung Yang, Chaim A Schramm, Laura Novik

Science· August 2021

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Antibodies with potent and broad neutralizing activity against antigenically diverse and highly transmissible SARS-CoV-2 variants.
Lingshu Wang, Tongqing Zhou, Yi Zhang, Eun Sung Yang, Chaim A Schramm, Laura Novik

bioRxiv· March 2021

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Safety, tolerability, pharmacokinetics, and immunogenicity of the therapeutic monoclonal antibody mAb114 targeting Ebola virus glycoprotein (VRC 608): an open-label phase 1 study.
Martin R Gaudinski, Emily E Coates, Laura Novik, Alicia Widge, Katherine V Houser

Lancet· March 2019

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Safety, tolerability, and immunogenicity of two Zika virus DNA vaccine candidates in healthy adults: randomised, open-label, phase 1 clinical trials.
Martin R Gaudinski, Katherine V Houser, Kaitlyn M Morabito, Zonghui Hu, Galina Yamshchikov, Laura Novik

Lancet· February 2018

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Safety and Immunogenicity of a rAd35-EnvA Prototype HIV-1 Vaccine in Combination with rAd5-EnvA in Healthy Adults (VRC 012).
Michelle C Crank, Eleanor M P Wilson, Laura Novik, Mary E Enama, Cynthia S Hendel

PLoS One· June 2017

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Chimpanzee Adenovirus Vector Ebola Vaccine.
Julie E Ledgerwood, Adam D DeZure, Daphne A Stanley, Emily E Coates, Laura Novik

N Engl J Med· March 2017

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Attenuated PfSPZ Vaccine induces strain-transcending T cells and durable protection against heterologous controlled human malaria infection.
Kirsten E Lyke, Andrew S Ishizuka, Andrea A Berry, Sumana Chakravarty, Adam DeZure, Laura Novik

Proc Natl Acad Sci U S A· March 2017

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Protection against malaria at 1 year and immune correlates following PfSPZ vaccination.
Andrew S Ishizuka, Kirsten E Lyke, Adam DeZure, Andrea A Berry, Thomas L Richie, Laura Novik

Nat Med· June 2016

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Corrigendum: Protection against malaria at 1 year and immune correlates following PfSPZ vaccination.
Andrew S Ishizuka, Kirsten E Lyke, Adam DeZure, Andrea A Berry, Thomas L Richie, Laura Novik

Nat Med· June 2016

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Homologous boosting with adenoviral serotype 5 HIV vaccine (rAd5) vector can boost antibody responses despite preexisting vector-specific immunity in a randomized phase I clinical trial.
Uzma N Sarwar, Laura Novik, Mary E Enama, Sarah A Plummer, Richard A Koup

PLoS One· June 2015

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Phase I randomized clinical trial of VRC DNA and rAd5 HIV-1 vaccine delivery by intramuscular (i.m.), subcutaneous (s.c.) and intradermal (i.d.) administration (VRC 011).
Mary E Enama, Julie E Ledgerwood, Laura Novik, Martha C Nason, Ingelise J Gordon

PLoS One· May 2015

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Protection against malaria by intravenous immunization with a nonreplicating sporozoite vaccine.
Robert A Seder, Lee-Jah Chang, Mary E Enama, Kathryn L Zephir, Uzma N Sarwar, Laura Novik

Science· September 2013

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Priming immunization with DNA augments immunogenicity of recombinant adenoviral vectors for both HIV-1 specific antibody and T-cell responses.
Richard A Koup, Mario Roederer, Laurie Lamoreaux, Jennifer Fischer, Laura Novik

PLoS One· February 2010

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