Publications by authors named "Laura San-Segundo"

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Neutrophil-mediated trogocytosis as a new mechanism of action of daratumumab.
Mauro Lorenzo-Mohamed, Carla Vicario-Bueno, Andrea Díaz-Tejedor, Marta González-Rodríguez, Bárbara Castellanos, Laura San-Segundo

Blood Neoplasia· November 2025

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EGFR amplification and EGFRvIII predict and participate in TAT-Cx43266-283 antitumor response in preclinical glioblastoma models.
Andrea Álvarez-Vázquez, Laura San-Segundo, Pilar Cerveró-García, Raquel Flores-Hernández, Claudia Ollauri-Ibáñez

Neuro Oncol· July 2024

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Tinostamustine (EDO-S101), an Alkylating Deacetylase Inhibitor, Enhances the Efficacy of Daratumumab in Multiple Myeloma by Upregulation of CD38 and NKG2D Ligands.
Andrea Díaz-Tejedor, Javier Rodríguez-Ubreva, Laura Ciudad, Mauro Lorenzo-Mohamed, Marta González-Rodríguez, Laura San-Segundo

Int J Mol Sci· April 2024

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Chloroquine-Induced DNA Damage Synergizes with Nonhomologous End Joining Inhibition to Cause Ovarian Cancer Cell Cytotoxicity.
María Ovejero-Sánchez, Jorge Rubio-Heras, María Del Carmen Vicente de la Peña, Laura San-Segundo, Jesús Pérez-Losada

Int J Mol Sci· July 2022

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Stroma-Mediated Resistance to S63845 and Venetoclax through MCL-1 and BCL-2 Expression Changes Induced by miR-193b-3p and miR-21-5p Dysregulation in Multiple Myeloma.
Esperanza M Algarín, Dalia Quwaider, Francisco J Campos-Laborie, Andrea Díaz-Tejedor, Pedro Mogollón, Laura San-Segundo

Cells· March 2021

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Targeting aberrant DNA methylation in mesenchymal stromal cells as a treatment for myeloma bone disease.
Antonio Garcia-Gomez, Tianlu Li, Carlos de la Calle-Fabregat, Javier Rodríguez-Ubreva, Laura Ciudad, Laura San-Segundo

Nat Commun· January 2021

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Protein Translation Inhibition is Involved in the Activity of the Pan-PIM Kinase Inhibitor PIM447 in Combination with Pomalidomide-Dexamethasone in Multiple Myeloma.
Teresa Paíno, Lorena González-Méndez, Laura San-Segundo, Luis A Corchete, Susana Hernández-García

Cancers (Basel)· September 2020

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CRISPR/Cas9-generated models uncover therapeutic vulnerabilities of del(11q) CLL cells to dual BCR and PARP inhibition.
Miguel Quijada-Álamo, María Hernández-Sánchez, Verónica Alonso-Pérez, Ana E Rodríguez-Vicente, Ignacio García-Tuñón

Leukemia· June 2020

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Preclinical evaluation of the simultaneous inhibition of MCL-1 and BCL-2 with the combination of S63845 and venetoclax in multiple myeloma.
Esperanza M Algarín, Andrea Díaz-Tejedor, Pedro Mogollón, Susana Hernández-García, Luis A Corchete, Laura San-Segundo

Haematologica· March 2020

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The kinesin spindle protein inhibitor filanesib enhances the activity of pomalidomide and dexamethasone in multiple myeloma.
Susana Hernández-García, Laura San-Segundo, Lorena González-Méndez, Luis A Corchete, Irena Misiewicz-Krzeminska

Haematologica· December 2017

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C3G promotes a selective release of angiogenic factors from activated mouse platelets to regulate angiogenesis and tumor metastasis.
Víctor Martín-Granado, Sara Ortiz-Rivero, Rita Carmona, Sara Gutiérrez-Herrero, Mario Barrera, Laura San-Segundo

Oncotarget· December 2017

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Amiloride, An Old Diuretic Drug, Is a Potential Therapeutic Agent for Multiple Myeloma.
Elizabeta A Rojas, Luis Antonio Corchete, Laura San-Segundo, Juan F Martínez-Blanch, Francisco M Codoñer

Clin Cancer Res· November 2017

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Preclinical anti-myeloma activity of EDO-S101, a new bendamustine-derived molecule with added HDACi activity, through potent DNA damage induction and impairment of DNA repair.
Ana-Alicia López-Iglesias, Ana B Herrero, Marta Chesi, Laura San-Segundo, Lorena González-Méndez

J Hematol Oncol· June 2017

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Correction: The PARP inhibitor olaparib enhances the sensitivity of Ewing sarcoma to trabectedin.
José Luis Ordóñez, Ana Teresa Amaral, Angel M Carcaboso, David Herrero-Martín, María Del Carmen García-Macías, Laura San-Segundo

Oncotarget· June 2017

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The Novel Pan-PIM Kinase Inhibitor, PIM447, Displays Dual Antimyeloma and Bone-Protective Effects, and Potently Synergizes with Current Standards of Care.
Teresa Paíno, Antonio Garcia-Gomez, Lorena González-Méndez, Laura San-Segundo, Susana Hernández-García

Clin Cancer Res· January 2017

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Synergistic DNA-damaging effect in multiple myeloma with the combination of zalypsis, bortezomib and dexamethasone.
Ana-Alicia López-Iglesias, Lorena González-Méndez, Laura San-Segundo, Ana B Herrero, Susana Hernández-García

Haematologica· January 2017

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Targeting of PI3K/AKT/mTOR pathway to inhibit T cell activation and prevent graft-versus-host disease development.
Mª Carmen Herrero-Sánchez, Concepción Rodríguez-Serrano, Julia Almeida, Laura San Segundo, Susana Inogés

J Hematol Oncol· October 2016

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Effects of dietary exposure of polycyclic musk HHCB on the metamorphosis of Xenopus laevis.
María Victoria Pablos, María Ángeles Jiménez, Laura San Segundo, Federica Martini, Eulalia Beltrán

Environ Toxicol Chem· June 2016

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Effect of mTORC1/mTORC2 inhibition on T cell function: potential role in graft-versus-host disease control.
Ma Carmen Herrero-Sánchez, Concepción Rodríguez-Serrano, Julia Almeida, Laura San-Segundo, Susana Inogés

Br J Haematol· June 2016

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Alterations in gene expression levels provide early indicators of chemical stress during Xenopus laevis embryo development: A case study with perfluorooctane sulfonate (PFOS).
Laura San-Segundo, Laura Guimarães, Carlos Fernández Torija, Eulalia M Beltrán, Lúcia Guilhermino

Ecotoxicol Environ Saf· May 2016

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PTPN13 and β-Catenin Regulate the Quiescence of Hematopoietic Stem Cells and Their Interaction with the Bone Marrow Niche.
Guillermo López-Ruano, Rodrigo Prieto-Bermejo, Teresa L Ramos, Laura San-Segundo, Luis Ignacio Sánchez-Abarca

Stem Cell Reports· October 2015

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Stage-dependent ethoxyresorufin-O-deethylase (EROD) in vivo activity in medaka (Oryzias latipes) embryos.
Miguel González-Doncel, Gregoria Carbonell, Laura San Segundo, Salvador Sastre, Eulalia M Beltrán

Chemosphere· September 2015

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The PARP inhibitor olaparib enhances the sensitivity of Ewing sarcoma to trabectedin.
José Luis Ordóñez, Ana Teresa Amaral, Angel M Carcaboso, David Herrero-Martín, María del Carmen García-Macías, Laura San-Segundo

Oncotarget· August 2015

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Phenotypic, genomic and functional characterization reveals no differences between CD138++ and CD138low subpopulations in multiple myeloma cell lines.
Teresa Paíno, María E Sarasquete, Bruno Paiva, Patryk Krzeminski, Laura San-Segundo

PLoS One· January 2015

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Embryonic exposure of medaka (Oryzias latipes) to propylparaben: effects on early development and post-hatching growth.
Miguel González-Doncel, José Enrique García-Mauriño, Laura San Segundo, Eulalia M Beltrán, Salvador Sastre

Environ Pollut· January 2014

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