Publications by authors named "Laura Spring"

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Current landscape of sequencing ADCs in metastatic breast cancer.
Shannon McLaughlin, Lis V Ravani, Beverly Moy, Arielle J Medford, Steven J Isakoff, Laura M Spring

Ther Adv Med Oncol· December 2025

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Genomic and proteomic profiling of GATA3 mutant metastatic hormone receptor-positive breast cancer and impact on clinical outcomes.
Arielle J Medford, Marko Velimirovic, Yifat Gefen, Andrzej Niemierko, Lorenzo Gerratana, Laura M Spring

Breast Cancer Res Treat· August 2025

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Selection biases in the systematic collection of breast biobank specimens.
Yael Bar, Gary X Wang, Gabrielle E Gioia, Geoffrey Fell, Shinn-Huey S Chou, Laura M Spring

NPJ Breast Cancer· August 2025

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TOP1 Mutations and Cross-Resistance to Antibody-Drug Conjugates in Patients with Metastatic Breast Cancer.
Rachel O Abelman, Bogang Wu, Haley Barnes, Arielle Medford, Bryanna Norden, Laura M Spring

Clin Cancer Res· May 2025

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Impact of Race/Ethnicity on Clinical and Genomic Characteristics, Trial Participation, and Genotype-Matched Therapy among Patients with Metastatic Breast Cancer.
Rupali Sood, Andrzej Niemierko, Lianne Ryan, Laura Spring, Beverly Moy

Clin Cancer Res· April 2025

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Dynamic HER2-low status among patients with triple negative breast cancer (TNBC) and the impact of repeat biopsies.
Yael Bar, Geoffrey Fell, Aylin Dedeoglu, Natalie Moffett, Neelima Vidula, Laura Spring

NPJ Breast Cancer· March 2025

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Pembrolizumab and chemotherapy in high-risk, early-stage, ER/HER2 breast cancer: a randomized phase 3 trial.
Fatima Cardoso, Joyce O'Shaughnessy, Zhenzhen Liu, Heather McArthur, Peter Schmid, Laura Spring

Nat Med· February 2025

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Adjuvant endocrine therapy with cyclin-dependent kinase 4/6 inhibitor, ribociclib, for localized hormone receptor-positive/HER2- breast cancer (LEADER).
Laura M Spring, Lauren Scarpetti, Arielle J Medford, Andrzej Niemierko, Amy Comander

NPJ Breast Cancer· January 2025

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A TROP2/Claudin Program Mediates Immune Exclusion to Impede Checkpoint Blockade in Breast Cancer.
Bogang Wu, Win Thant, Elena Bitman, Ting Liu, Jie Liu, Laura M Spring

bioRxiv· December 2024

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Real-world use patterns, effectiveness, and tolerability of sacituzumab govitecan for second-line and later-line treatment of metastatic triple-negative breast cancer in the United States.
Kevin Kalinsky, Laura Spring, Clinton Yam, Manali Ajay Bhave, Ioanna Ntalla

Breast Cancer Res Treat· November 2024

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Antibody-Drug Conjugate Sacituzumab Govitecan Enables a Sequential TOP1/PARP Inhibitor Therapy Strategy in Patients with Breast Cancer.
Aditya Bardia, Sheng Sun, Nayana Thimmiah, James T Coates, Bogang Wu, Laura Spring

Clin Cancer Res· July 2024

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Searching for the "Holy Grail" of breast cancer recurrence risk: a narrative review of the hunt for a better biomarker and the promise of circulating tumor DNA (ctDNA).
Lucy Gao, Arielle Medford, Laura Spring, Yael Bar, Bonnie Hu

Breast Cancer Res Treat· June 2024

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Novel oral selective estrogen receptor degraders (SERDs) to target hormone receptor positive breast cancer: elacestrant as the poster-child.
Jennifer C Keenan, Arielle J Medford, Charles S Dai, Seth A Wander, Laura M Spring

Expert Rev Anticancer Ther· June 2024

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Axillary Nodal Response to Neoadjuvant T-DM1 Combined with Pertuzumab in a Prospective Phase II Multi-Institution Clinical Trial.
Anna Weiss, Qingchun Jin, Adrienne G Waks, Denise Yardley, Laura M Spring

J Am Coll Surg· March 2024

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Allosteric PI3Kα Inhibition Overcomes On-target Resistance to Orthosteric Inhibitors Mediated by Secondary PIK3CA Mutations.
Andreas Varkaris, Ferran Fece de la Cruz, Elizabeth E Martin, Bryanna L Norden, Nicholas Chevalier, Laura M Spring

Cancer Discov· February 2024

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HER2 heterogeneity and treatment response-associated profiles in HER2-positive breast cancer in the NCT02326974 clinical trial.
Zheqi Li, Otto Metzger Filho, Giuseppe Viale, Patrizia dell'Orto, Leila Russo, Laura M Spring

J Clin Invest· February 2024

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Virtual Molecular and Precision Medicine Clinic to Improve Access to Clinical Trials for Patients With Metastatic Breast Cancer: An Academic/Community Collaboration.
Laura M Spring, Lindsey Mortensen, Elizabeth Abraham, Jennifer Keenan, Arielle Medford

JCO Oncol Pract· January 2024

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Managing hyperglycemia and rash associated with alpelisib: expert consensus recommendations using the Delphi technique.
Emily J Gallagher, Heather Moore, Mario E Lacouture, Susan F Dent, Azeez Farooki, Laura Spring

NPJ Breast Cancer· January 2024

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Molecular Residual Disease in Breast Cancer: Detection and Therapeutic Interception.
Arielle J Medford, Beverly Moy, Laura M Spring, Sara A Hurvitz, Nicholas C Turner

Clin Cancer Res· November 2023

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Endocrine Therapy for Surgeons: Practical Pearls for Managing Menopausal, Bone Loss and Sexual Adverse Effects.
Kristin Rojas, Laura M Spring, Liz O'Riordan, Anna Weiss

Ann Surg Oncol· October 2023

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Impact of Neoadjuvant Paclitaxel/Trastuzumab/Pertuzumab on Breast Tumor Downsizing for Patients with HER2+ Breast Cancer: Single-Arm Prospective Clinical Trial.
Anna Weiss, Tianyu Li, Neelam V Desai, Nadine M Tung, Philip D Poorvu, Laura M Spring

J Am Coll Surg· August 2023

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Feasibility of introducing a smartphone navigation application into the care of breast cancer patients (The FIONA Study).
Steven J Isakoff, Maya R Said, Agnes H Kwak, Eva Glieberman, Emily A O'Rourke, Laura M Spring

Breast Cancer Res Treat· June 2023

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Editorial: Steroid hormone receptors and cell cycle in breast cancer.
Victoria T Fabris, Laura Spring, Luisa A Helguero

Front Endocrinol (Lausanne)· May 2023

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A Gene Panel Associated With Abemaciclib Utility in -Mutated Breast Cancer After Prior Cyclin-Dependent Kinase 4/6-Inhibitor Progression.
Jamie O Brett, Taronish D Dubash, Gabriela N Johnson, Andrzej Niemierko, Veronica Mariotti, Laura M Spring

JCO Precis Oncol· May 2023

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