Publications by authors named "Laura Zelarayan"

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Dot1L-H3K79me2-Tbx6 Axis: A Novel Therapeutic Target for Preventing Cardiac Failure.
Tomás M Peralta, Laura C Zelarayán

Circ Res· August 2025

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Glycogen synthase kinase-3 inhibition and insulin enhance proliferation and inhibit maturation of human iPSC-derived cardiomyocytes via TCF and FOXO signaling.
Qianliang Yuan, Devin Verbueken, Rafeeh Dinani, Rosa Kim, Eric Schoger, Laura Cecilia Zelarayan

Stem Cell Reports· January 2025

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Physiologists as medical scientists: An early warning from the German academic system.
Katrin Streckfuss-Bömeke, Nicolle Kränkel, Christoph Maack, Renate B Schnabel, Laura C Zelarayán

Physiol Rep· November 2024

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Human induced pluripotent stem cells for live cell cycle monitoring and endogenous gene activation.
Rosa Kim, Sebastian H Nagel, Norman Y Liaw, Wolfram-H Zimmermann, Laura C Zelarayán

Stem Cell Res· October 2024

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Transient stabilization of human cardiovascular progenitor cells from human pluripotent stem cells in vitro reflects stage-specific heart development in vivo.
Emiliano Bolesani, Dorothee Bornhorst, Lavanya M Iyer, Dorota Zawada, Nina Friese

Cardiovasc Res· September 2024

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Author Correction: Single-cell transcriptomics reveal extracellular vesicles secretion with a cardiomyocyte proteostasis signature during pathological remodeling.
Eric Schoger, Federico Bleckwedel, Giulia Germena, Cheila Rocha, Petra Tucholla

Commun Biol· May 2024

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Preclinical evaluation of CRISPR-based therapies for Noonan syndrome caused by deep-intronic variants.
Carolin Knauer, Henrike Haltern, Eric Schoger, Sebastian Kügler, Lennart Roos

Mol Ther Nucleic Acids· March 2024

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Droplet Digital PCR Is a Novel Screening Method Identifying Potential Cardiac G-Protein-Coupled Receptors as Candidate Pharmacological Targets in a Rat Model of Pressure-Overload-Induced Cardiac Dysfunction.
Nabil V Sayour, Viktória É Tóth, Regina N Nagy, Imre Vörös, Tamás G Gergely

Int J Mol Sci· September 2023

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Moving toward gender equity in the cardiology and cardiovascular research workforce in Germany: a report from the German Cardiac Society.
Carolin Lerchenmüller, Laura Zelarayan, Katrin Streckfuss-Bömeke, Maria Rubini Gimenez, Renate Schnabel

Eur Heart J Open· March 2023

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Single-cell transcriptomics reveal extracellular vesicles secretion with a cardiomyocyte proteostasis signature during pathological remodeling.
Eric Schoger, Federico Bleckwedel, Giulia Germena, Cheila Rocha, Petra Tucholla

Commun Biol· January 2023

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Enhancing Cardiomyocyte Transcription Using In Vivo CRISPR/Cas9 Systems.
Eric Schoger, Laura C Zelarayán

Methods Mol Biol· September 2022

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Inactivation of Fgf3 and Fgf4 within the Fgf3/Fgf4/Fgf15 gene cluster reveals their redundant requirement for mouse inner ear induction and embryonic survival.
Laura Zelarayan, Victor Vendrell, Elena Domínguez-Frutos, Iris López-Hernández, Kiril Schimmang-Alonso

Dev Dyn· May 2022

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A novel single-cell RNA-sequencing approach and its applicability connecting genotype to phenotype in ageing disease.
Orr Shomroni, Maren Sitte, Julia Schmidt, Sabnam Parbin, Fabian Ludewig, Laura Cecilia Zelarayan

Sci Rep· March 2022

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Cellular Chitchatting: Exploring the Role of Exosomes as Cardiovascular Risk Factors.
Giulia Germena, Laura Cecilia Zelarayán, Rabea Hinkel

Front Cell Dev Biol· March 2022

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Tailoring Cardiac Synthetic Transcriptional Modulation Towards Precision Medicine.
Eric Schoger, Sara Lelek, Daniela Panáková, Laura Cecilia Zelarayán

Front Cardiovasc Med· January 2022

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Establishment of a second generation homozygous CRISPRa human induced pluripotent stem cell (hiPSC) line for enhanced levels of endogenous gene activation.
Eric Schoger, Wolfram-Hubertus Zimmermann, Lukas Cyganek, Laura Cecilia Zelarayán

Stem Cell Res· October 2021

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Management of Metadata Types in Basic Cardiological Research.
Harald Kusch, Robert Kossen, Markus Suhr, Luca Freckmann, Linus Weber

Stud Health Technol Inform· September 2021

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Reversible reprogramming of cardiomyocytes to a fetal state drives heart regeneration in mice.
Yanpu Chen, Felipe F Lüttmann, Eric Schoger, Hans R Schöler, Laura C Zelarayán

Science· September 2021

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Establishment of two homozygous CRISPR interference (CRISPRi) knock-in human induced pluripotent stem cell (hiPSC) lines for titratable endogenous gene repression.
Eric Schoger, Wolfram-Hubertus Zimmermann, Lukas Cyganek, Laura Cecilia Zelarayán

Stem Cell Res· August 2021

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Preclinical evidence for the therapeutic value of TBX5 normalization in arrhythmia control.
Franziska S Rathjens, Alica Blenkle, Lavanya M Iyer, Anke Renger, Fahima Syeda, Laura C Zelarayan

Cardiovasc Res· July 2021

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RhoGEF17-An Essential Regulator of Endothelial Cell Death and Growth.
Pamina Weber, Doris Baltus, Aline Jatho, Oliver Drews, Laura C Zelarayan

Cells· March 2021

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Generation of homozygous CRISPRa human induced pluripotent stem cell (hiPSC) lines for sustained endogenous gene activation.
Eric Schoger, Loukas Argyriou, Wolfram-Hubertus Zimmermann, Lukas Cyganek, Laura Cecilia Zelarayán

Stem Cell Res· October 2020

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Inhibition of Prolyl-Hydroxylase Domain Enzymes Protects From Reoxygenation Injury in Engineered Human Myocardium.
Elif Levent, Claudia Noack, Laura C Zelarayán, Dörthe M Katschinski, Wolfram-Hubertus Zimmermann

Circulation· October 2020

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Dysferlin links excitation-contraction coupling to structure and maintenance of the cardiac transverse-axial tubule system.
Julia Hofhuis, Kristina Bersch, Stefan Wagner, Cristina Molina, Funsho E Fakuade

Europace· July 2020

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CRISPR-Mediated Activation of Endogenous Gene Expression in the Postnatal Heart.
Eric Schoger, Kelli J Carroll, Lavanya M Iyer, John R McAnally, Wei Tan

Circ Res· January 2020

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