Publications by authors named "Lauren Testa"

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Liver-directed base editing of prevents ectopic calcification in a variant-humanized mouse model of pseudoxanthoma elasticum.
Lauren C Testa, Dora Obiri-Yeboah, Hooda Said, Ping Qu, Michael A Levine

Mol Ther Nucleic Acids· December 2025

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Improved specificity and efficiency of in vivo adenine base editing therapies with hybrid guide RNAs.
Madelynn N Whittaker, Lauren C Testa, Aidan Quigley, Dominique L Brooks, Sarah A Grandinette

Nat Biomed Eng· October 2025

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Improved specificity and efficiency of adenine base editing therapies with hybrid guide RNAs.
Madelynn N Whittaker, Lauren C Testa, Dominique L Brooks, Aidan Quigley, Hooda Said

bioRxiv· April 2025

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Patient-Scientist Perspective on Developing Genetic Therapies for Marfan Syndrome.
Lauren C Testa

Circ Genom Precis Med· April 2025

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Epigenome Editing Durability Varies Widely Across Cardiovascular Disease Target Genes.
Madelynn N Whittaker, Lauren C Testa, Aidan Quigley, Ishaan Jindal, Saúl V Cortez-Alvarado

Arterioscler Thromb Vasc Biol· October 2023

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Base Editing and Prime Editing: Potential Therapeutic Options for Rare and Common Diseases.
Lauren C Testa, Kiran Musunuru

BioDrugs· July 2023

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Epigenome Editing Durability Varies Widely Across Cardiovascular Disease Target Genes.
Madelynn N Whittaker, Lauren C Testa, Aidan Quigley, Ishaan Jindal, Saúl V Cortez-Alvarado

bioRxiv· May 2023

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Dysregulated myosin in Hermansky-Pudlak syndrome lung fibroblasts is associated with increased cell motility.
Jewel Imani, Steven P M Bodine, Anthony M Lamattina, Diane D Ma, Shikshya Shrestha, Lauren C Testa

Respir Res· June 2022

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Progressive pulmonary fibrosis in a murine model of Hermansky-Pudlak syndrome.
Shachar Abudi-Sinreich, Steven P Bodine, Tadafumi Yokoyama, Nathanial J Tolman, Michal Tyrlik, Lauren C Testa

Respir Res· May 2022

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Automated Digital Quantification of Pulmonary Fibrosis in Human Histopathology Specimens.
Lauren C Testa, Yvon Jule, Linnea Lundh, Karine Bertotti, Melissa A Merideth

Front Med (Lausanne)· June 2021

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The assembly and evaluation of antisense oligonucleotides applied in exon skipping for titin-based mutations in dilated cardiomyopathy.
Julia Kelley Hahn, Balram Neupane, Kabita Pradhan, Qifeng Zhou, Lauren Testa

J Mol Cell Cardiol· June 2019

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Low Back Pain, a Comprehensive Review: Pathophysiology, Diagnosis, and Treatment.
Ivan Urits, Aaron Burshtein, Medha Sharma, Lauren Testa, Peter A Gold

Curr Pain Headache Rep· March 2019

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Characteristics of the cation cotransporter NKCC1 in human brain: alternate transcripts, expression in development, and potential relationships to brain function and schizophrenia.
Yukitaka Morita, Joseph H Callicott, Lauren R Testa, Michelle I Mighdoll, Dwight Dickinson

J Neurosci· April 2014

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