Publications by authors named "Laurence D Hurst"

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Bacterial gene 5' ends have unusual mutation rates that can mislead tests of selection.
Sofia Radrizzani, Juan Rivas-Santisteban, Namshik Han, Laurence D Hurst

PLoS Biol· December 2025

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ERV3-MLT1 provides cis-regulatory elements for human placental functioning and are commonly dysregulated in human-specific preeclampsia.
Rabia Anwar, Amit Pande, Manvendra Singh, Zhi Huang, Eve Hallett, Laurence D Hurst

Genome Biol· November 2025

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Cell Compartment is a Predictor of Protein Rate of Evolution, but not in the Manner Expected: Evidence Against the Extended Complexity Hypothesis.
Juan Rivas-Santisteban, Pablo Yubero, Laurence D Hurst

Genome Biol Evol· July 2025

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Co-option of an endogenous retrovirus (LTR7-HERVH) in early human embryogenesis: becoming useful and going unnoticed.
Zsuzsanna Izsvák, Jin Ma, Manvendra Singh, Laurence D Hurst

Mob DNA· July 2025

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Why AGG is associated with high transgene output: passenger effects and their implications for transgene design.
Kate G Daniels, Sofia Radrizzani, Laurence D Hurst

NAR Genom Bioinform· June 2025

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RID is required for both repeat-induced point mutation and nucleation of a novel transitional heterochromatic state for euchromatic repeats.
Zhen He, Nannan Wu, Ruonan Yao, Huawei Tan, Yingying Sun, Laurence D Hurst

Nucleic Acids Res· March 2025

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Selection on synonymous sites: the unwanted transcript hypothesis.
Sofia Radrizzani, Grzegorz Kudla, Zsuzsanna Izsvák, Laurence D Hurst

Nat Rev Genet· June 2024

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Epistasis, core-genome disharmony, and adaptation in recombining bacteria.
Aidan J Taylor, Koji Yahara, Ben Pascoe, Seungwon Ko, Leonardos Mageiros, Laurence D Hurst

mBio· June 2024

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Genes for highly abundant proteins in Escherichia coli avoid 5' codons that promote ribosomal initiation.
Loveday E Lewin, Kate G Daniels, Laurence D Hurst

PLoS Comput Biol· October 2023

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Staring at the onco-exaptation: the two-faced medley of an ancient retrovirus, HERVH.
Manvendra Singh, Aleksandra M Kondraskhina, Laurence D Hurst, Zsuzsanna Izsvák

J Clin Invest· July 2023

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Re-evaluating evidence for adaptive mutation rate variation.
Long Wang, Alexander T Ho, Laurence D Hurst, Sihai Yang

Nature· July 2023

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A new human embryonic cell type associated with activity of young transposable elements allows definition of the inner cell mass.
Manvendra Singh, Aleksandra M Kondrashkina, Thomas J Widmann, Jose L Cortes, Vikas Bansal, Laurence D Hurst

PLoS Biol· June 2023

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Both trust in, and polarization of trust in, relevant sciences have increased through the COVID-19 pandemic.
Sofia Radrizzani, Cristina Fonseca, Alison Woollard, Jonathan Pettitt, Laurence D Hurst

PLoS One· March 2023

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People with more extreme attitudes towards science have self-confidence in their understanding of science, even if this is not justified.
Cristina Fonseca, Jonathan Pettitt, Alison Woollard, Adam Rutherford, Wendy Bickmore, Laurence D Hurst

PLoS Biol· January 2023

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A Novel Gene Controls a New Structure: PiggyBac Transposable Element-Derived 1, Unique to Mammals, Controls Mammal-Specific Neuronal Paraspeckles.
Tamás Raskó, Amit Pande, Kathrin Radscheit, Annika Zink, Manvendra Singh, Laurence D Hurst

Mol Biol Evol· October 2022

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Stop Codon Usage as a Window into Genome Evolution: Mutation, Selection, Biased Gene Conversion and the TAG Paradox.
Alexander T Ho, Laurence D Hurst

Genome Biol Evol· August 2022

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Selfish centromeres and the wastefulness of human reproduction.
Laurence D Hurst

PLoS Biol· July 2022

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Dynamic reprogramming of H3K9me3 at hominoid-specific retrotransposons during human preimplantation development.
Hanwen Yu, Manqi Chen, Yuanlang Hu, Songbang Ou, Xiu Yu, Laurence D Hurst

Cell Stem Cell· July 2022

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Unusual mammalian usage of TGA stop codons reveals that sequence conservation need not imply purifying selection.
Alexander Thomas Ho, Laurence Daniel Hurst

PLoS Biol· May 2022

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Transgene-design: a web application for the design of mammalian transgenes.
Stefanie Mühlhausen, Laurence D Hurst

Bioinformatics· April 2022

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In rice splice variants that restore the reading frame after frameshifting indel introduction are common, often induced by the indels and sometimes lead to organism-level rescue.
Yanxiao Jia, Chao Qin, Milton Brian Traw, Xiaonan Chen, Ying He, Laurence D Hurst

PLoS Genet· February 2022

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Variation in Release Factor Abundance Is Not Needed to Explain Trends in Bacterial Stop Codon Usage.
Alexander T Ho, Laurence D Hurst

Mol Biol Evol· January 2022

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Evidence from Drosophila Supports Higher Duplicability of Faster Evolving Genes.
Zoe Vance, Lukasz Niezabitowski, Laurence D Hurst, Aoife McLysaght

Genome Biol Evol· January 2022

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Corrigendum to: Evidence for Strong Mutation Bias toward, and Selection against, U Content in SARS-CoV-2: Implications for Vaccine Design.
Alan M Rice, Atahualpa Castillo Morales, Alexander T Ho, Christine Mordstein, Stefanie Mühlhausen, Laurence D Hurst

Mol Biol Evol· October 2021

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Evidence in disease and non-disease contexts that nonsense mutations cause altered splicing via motif disruption.
Liam Abrahams, Rosina Savisaar, Christine Mordstein, Bethan Young, Grzegorz Kudla, Laurence D Hurst

Nucleic Acids Res· September 2021

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