Publications by authors named "Lawrence Friedhoff"

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A call for a global 'bigger' data approach to Alzheimer disease.
Eric Perakslis, Henry Riordan, Lawrence Friedhoff, Azmi Nabulsi, Emilio Merlo Pich

Nat Rev Drug Discov· May 2019

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Functional neurotoxicity evaluation of noribogaine using video-EEG in cynomolgus monkeys.
Simon Authier, Michael V Accardi, Dominique Paquette, Mylène Pouliot, Joseph Arezzo, Lawrence T Friedhoff

J Pharmacol Toxicol Methods· May 2017

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Ascending Single-Dose, Double-Blind, Placebo-Controlled Safety Study of Noribogaine in Opioid-Dependent Patients.
Paul Glue, Gavin Cape, Donna Tunnicliff, Michelle Lockhart, Fred Lam, Lawrence Friedhoff

Clin Pharmacol Drug Dev· November 2016

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Switching Opioid-Dependent Patients From Methadone to Morphine: Safety, Tolerability, and Methadone Pharmacokinetics.
Paul Glue, Gavin Cape, Donna Tunnicliff, Michelle Lockhart, Fred Lam, Lawrence Friedhoff

J Clin Pharmacol· August 2016

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Lost interest for existing compounds: New boosts.
Lawrence T Friedhoff, James Dailey

Eur Neuropsychopharmacol· July 2015

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Ascending-dose study of noribogaine in healthy volunteers: pharmacokinetics, pharmacodynamics, safety, and tolerability.
Paul Glue, Michelle Lockhart, Fred Lam, Noelyn Hung, Cheung-Tak Hung, Lawrence Friedhoff

J Clin Pharmacol· February 2015

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Cyclin-dependent kinase 8 mediates chemotherapy-induced tumor-promoting paracrine activities.
Donald C Porter, Elena Farmaki, Serena Altilia, Gary P Schools, Deborah K West, Lawrence T Friedhoff

Proc Natl Acad Sci U S A· August 2012

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Phenserine efficacy in Alzheimer's disease.
Bengt Winblad, Ezio Giacobini, Lutz Frölich, Lawrence T Friedhoff, Gosse Bruinsma

J Alzheimers Dis· May 2011

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Pharmacokinetics and dose proportionality of extended-release metformin following administration of 1000, 1500, 2000 and 2500 mg in healthy volunteers.
Edward Cullen, James Liao, Peter Lukacsko, Robert Niecestro, Lawrence Friedhoff

Biopharm Drug Dispos· September 2004

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Pharmacokinetics of lovastatin extended-release dosage form (Lovastatin XL) in healthy volunteers.
Michael Lamson, Gale Phillips, Jason Shen, Peter Lukacsko, Lawrence Friedhoff

Biopharm Drug Dispos· May 2002

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Pharmacological concentrations of the HMG-CoA reductase inhibitor lovastatin decrease the formation of the Alzheimer beta-amyloid peptide in vitro and in patients.
Joseph D Buxbaum, Edward I Cullen, Lawrence T Friedhoff

Front Biosci· April 2002

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Comparative pharmacokinetics of lovastatin extended-release tablets and lovastatin immediate-release tablets in humans.
Jim X Sun, Robert Niecestro, Gale Phillips, Jason Shen, Peter Lukacsko, Lawrence Friedhoff

J Clin Pharmacol· February 2002

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Dose response, safety, and efficacy of an extended-release formulation of lovastatin in adults with hypercholesterolemia.
John R Crouse, Peter Lukacsko, Robert Niecestro, Lawrence Friedhoff

Am J Cardiol· January 2002

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A multiple-dose pharmacodynamic, safety, and pharmacokinetic comparison of extended- and immediate-release formulations of lovastatin.
Michael H Davidson, Peter Lukacsko, Jim X Sun, Gale Phillips, Edward Walters, Lawrence Friedhoff

Clin Ther· January 2002

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Cholesterol depletion with physiological concentrations of a statin decreases the formation of the Alzheimer amyloid Abeta peptide.
Joseph D. Buxbaum, Neil S.M. Geoghagen, Lawrence T. Friedhoff

J Alzheimers Dis· April 2001

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