Publications by authors named "Lea Abildgaard"

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Na1.5 or K2 channel blockade does not increase arrhythmia risk in hypokalemic rabbit hearts, unlike K11.1 inhibition with dofetilide.
Yannan Yan, Lea Abildgaard, Mark Alexander Skarsfeldt, Sofia Hammami Bomholtz, Ulrik Sørensen

Int J Cardiol Heart Vasc· August 2025

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Mechanisms of Action of the KCa2-Negative Modulator AP30663, a Novel Compound in Development for Treatment of Atrial Fibrillation in Man.
Bo Hjorth Bentzen, Sofia Hammami Bomholtz, Rafel Simó-Vicens, Lasse Folkersen, Lea Abildgaard

Front Pharmacol· May 2020

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Inhibition of K2 Channels Decreased the Risk of Ventricular Arrhythmia in the Guinea Pig Heart During Induced Hypokalemia.
Jonas Goldin Diness, Lea Abildgaard, Sofia Hammami Bomholtz, Mark Alexander Skarsfeldt, Nils Edvardsson

Front Pharmacol· May 2020

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The K2 Channel Inhibitor AP30663 Selectively Increases Atrial Refractoriness, Converts Vernakalant-Resistant Atrial Fibrillation and Prevents Its Reinduction in Conscious Pigs.
Jonas Goldin Diness, Jeppe Egedal Kirchhoff, Tobias Speerschneider, Lea Abildgaard, Nils Edvardsson

Front Pharmacol· February 2020

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The K2 Channel Inhibitor AP14145, But Not Dofetilide or Ondansetron, Provides Functional Atrial Selectivity in Guinea Pig Hearts.
Jeppe Egedal Kirchhoff, Mark Alexander Skarsfeldt, Kalai Mangai Muthukumarasamy, Rafel Simó-Vicens, Sofia Hammami Bomholtz, Lea Abildgaard

Front Pharmacol· June 2019

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A new negative allosteric modulator, AP14145, for the study of small conductance calcium-activated potassium (K 2) channels.
Rafel Simó-Vicens, Jeppe E Kirchhoff, Bernardo Dolce, Lea Abildgaard, Tobias Speerschneider

Br J Pharmacol· December 2017

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Antiarrhythmic effect of the Ca-activated K (SK) channel inhibitor ICA combined with either amiodarone or dofetilide in an isolated heart model of atrial fibrillation.
Jeppe Egedal Kirchhoff, Jonas Goldin Diness, Lea Abildgaard, Majid Sheykhzade, Morten Grunnet

Pflugers Arch· November 2016

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pH-dependent inhibition of K₂P3.1 prolongs atrial refractoriness in whole hearts.
Mark A Skarsfeldt, Thomas A Jepps, Sofia H Bomholtz, Lea Abildgaard, Ulrik S Sørensen

Pflugers Arch· April 2016

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