Publications by authors named "Lea M D Delbridge"

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Diabetic heart shows preferential secretion of inner mitochondrial membrane proteins in the presence of mitochondrial oxidative stress.
Paula M Miotto, Jacqueline Bayliss, Gio Fidelito, James R Bell, Lea M D Delbridge

Am J Physiol Endocrinol Metab· December 2025

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Mechanical loading reveals an intrinsic cardiomyocyte stiffness contribution to diastolic dysfunction in murine cardiometabolic disease.
Johannes V Janssens, Antonia J A Raaijmakers, Parisa Koutsifeli, Kate L Weeks, James R Bell, Lea M D Delbridge

J Physiol· December 2024

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Mechanical loading reveals an intrinsic cardiomyocyte stiffness contribution to diastolic dysfunction in murine cardiometabolic disease.
Johannes V Janssens, Antonia J A Raaijmakers, Parisa Koutsifeli, Kate L Weeks, James R Bell, Lea M D Delbridge

bioRxiv· November 2024

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Sex-specific regulation of the cardiac transcriptome by the protein phosphatase 2A regulatory subunit B55α.
Nicola M Sergienko, Adam J Trewin, Helen Kiriazis, Antonia J A Raaijmakers, Daniel G Donner, Lea M D Delbridge

NPJ Metab Health Dis· November 2024

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Male and female atria exhibit distinct acute electrophysiological responses to sex steroids.
Simon P Wells, Christopher O'Shea, Sarah Hayes, Kate L Weeks, Paulus Kirchhof, Lea M D Delbridge

J Mol Cell Cardiol Plus· September 2024

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Methods for detection of cardiac glycogen-autophagy.
Parisa Koutsifeli, Lorna J Daniels, Joshua Neale, Sarah Fong, Upasna Varma, Lea M D Delbridge

Autophagy Rep· September 2024

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Male autism spectrum disorder is linked to brain aromatase disruption by prenatal BPA in multimodal investigations and 10HDA ameliorates the related mouse phenotype.
Christos Symeonides, Kristina Vacy, Sarah Thomson, Sam Tanner, Hui Kheng Chua, Lea M Durham Delbridge

Nat Commun· August 2024

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Methods for detection of cardiac glycogen-autophagy.
Parisa Koutsifeli, Lorna J Daniels, Joshua Neale, Sarah Fong, Upasna Varma, Lea M D Delbridge

bioRxiv· August 2024

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Myocardial glycophagy flux dysregulation and glycogen accumulation characterize diabetic cardiomyopathy.
Kimberley M Mellor, Upasna Varma, Parisa Koutsifeli, Lorna J Daniels, Victoria L Benson, Lea M D Delbridge

J Mol Cell Cardiol· April 2024

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The cardiomyocyte origins of diastolic dysfunction: cellular components of myocardial "stiffness".
Johannes V Janssens, Antonia J A Raaijmakers, Kate L Weeks, James R Bell, Kimberley M Mellor, Lea M D Delbridge

Am J Physiol Heart Circ Physiol· March 2024

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A gene therapy targeting medium-chain acyl-CoA dehydrogenase (MCAD) did not protect against diabetes-induced cardiac pathology.
Kate L Weeks, Helen Kiriazis, Glenn D Wadley, Emma I Masterman, Nicola M Sergienko, Lea M D Delbridge

J Mol Med (Berl)· January 2024

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Localized cardiomyocyte lipid accumulation is associated with slowed epicardial conduction in rats.
Simon P Wells, Antonia J A Raaijmakers, Claire L Curl, Christopher O'Shea, Sarah Hayes, Lea M D Delbridge

J Gen Physiol· November 2023

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Cellular Mechanisms Mediating Exercise-Induced Protection against Cardiotoxic Anthracycline Cancer Therapy.
Sanela Dozic, Erin J Howden, James R Bell, Kimberley M Mellor, Lea M D Delbridge

Cells· May 2023

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A novel small molecule inhibitor of human Drp1.
Ayeshah A Rosdah, Belinda M Abbott, Christopher G Langendorf, Yali Deng, Jia Q Truong, Lea M D Delbridge

Sci Rep· December 2022

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The big picture: cardiac sex-age interactions and proteogenomic insights.
Johannes V Janssens, James R Bell, Kate L Weeks, Kimberley M Mellor, Lea M D Delbridge

Am J Physiol Heart Circ Physiol· October 2022

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Glycogen-autophagy: Molecular machinery and cellular mechanisms of glycophagy.
Parisa Koutsifeli, Upasna Varma, Lorna J Daniels, Marco Annandale, Xun Li, Lea M D Delbridge

J Biol Chem· July 2022

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New Perspectives on Sex Steroid and Mineralocorticoid Receptor Signaling in Cardiac Ischemic Injury.
Laura A Bienvenu, James R Bell, Kate L Weeks, Lea M D Delbridge, Morag J Young

Front Physiol· June 2022

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Protein phosphatase 2A in the healthy and failing heart: New insights and therapeutic opportunities.
Nicola M Sergienko, Daniel G Donner, Lea M D Delbridge, Julie R McMullen, Kate L Weeks

Cell Signal· March 2022

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Cardiac mechanical efficiency is preserved in primary cardiac hypertrophy despite impaired mechanical function.
June-Chiew Han, Kenneth Tran, David J Crossman, Claire L Curl, Parisa Koutsifeli, Lea M D Delbridge

J Gen Physiol· August 2021

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Systematic quantification of histologic ventricular fibrosis in isolated mitral valve prolapse and sudden cardiac death.
Hui-Chen Han, Sarah A Parsons, Claire L Curl, Andrew W Teh, Antonia J A Raaijmakers, Lea M D Delbridge

Heart Rhythm· April 2021

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Elevated myocardial fructose and sorbitol levels are associated with diastolic dysfunction in diabetic patients, and cardiomyocyte lipid inclusions in vitro.
Lorna J Daniels, Marco Annandale, Parisa Koutsifeli, Xun Li, Carol T Bussey, Lea M D Delbridge

Nutr Diabetes· February 2021

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Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition).
Daniel J Klionsky, Amal Kamal Abdel-Aziz, Sara Abdelfatah, Mahmoud Abdellatif, Asghar Abdoli, Lea M D Delbridge

Autophagy· January 2021

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New perspectives on the role of Drp1 isoforms in regulating mitochondrial pathophysiology.
Ayeshah A Rosdah, William J Smiles, Jonathan S Oakhill, John W Scott, Christopher G Langendorf, Lea M D Delbridge

Pharmacol Ther· September 2020

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Epicardial Adipose Tissue Accumulation Confers Atrial Conduction Abnormality.
Chrishan J Nalliah, James R Bell, Antonia J A Raaijmakers, Helen M Waddell, Simon P Wells, Lea M D Delbridge

J Am Coll Cardiol· September 2020

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HFpEF-Time to Explore the Role of Genetic Heterogeneity in Phenotypic Variability: New Mechanistic Insights Offer Promise for Personalized Therapies.
Enzo R Porrello, Lea M D Delbridge

Circulation· November 2019

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