Publications by authors named "Lea Wagmann"

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Capillary blood microsampling and LC-Orbitrap analysis for adherence monitoring of cardiovascular drugs: method development, cross-validation, and patient proof-of-concept using VAMS and Capitainer-B.
Diana Kretschmer, Mert Tokcan, Philipp Markwirth, Lea Wagmann, Felix Mahfoud

Talanta· December 2025

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Polyclonal antibodies towards abrin and ricin-design and potential application for mass spectrometry-based analysis of human biosamples.
Aline C Vollmer, Claudia Fecher-Trost, Martin Jung, Marnie Cole, Tilman F Arnst, Lea Wagmann

Arch Toxicol· November 2025

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Optimizing multiomics sample preparation: comparative evaluation of extraction protocols for HepG2 cells.
Tilman F Arnst, Selina Hemmer, Claudia Fecher-Trost, Lea Wagmann, Markus R Meyer

Anal Bioanal Chem· November 2025

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Comprehensive Qualitative Drug Screening in Emergency Toxicology Using an Automated LC-MS System:Simultaneous Quantification of Relevant Drugs and Metabolites in Blood Plasma.
Selina Hemmer, Maximilian Ninnig, Lea Wagmann, Sascha K Manier, Markus R Meyer

Drug Test Anal· September 2025

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Lateral flow immunoassay for amatoxins detection in human urine compared to liquid chromatography-high-resolution tandem mass spectrometry.
Aline C Vollmer, Thomas P Bambauer, Candace B Bever, Christina C Tam, Lea Wagmann

J Anal Toxicol· September 2025

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Overcoming limitations in exhaled breath aerosol analysis - Untargeted breathomics for the identification of endogenous breath biomarkers using LC-HRMS/MS.
Juel Maalouli Schaar, Selina Hemmer, Sascha K Manier, Lea Wagmann, Markus R Meyer

Anal Chim Acta· September 2025

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In vitro toxicokinetics and metabolic profiling of methoxycathinones and methylthiocathinones using human liver systems and hyphenated mass spectrometry.
Matthias D Kroesen, Tanja M Gampfer, Lea Wagmann, Pierce V Kavanagh, Simon D Brandt

Arch Toxicol· September 2025

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Studies on the Stability and Microbial Biotransformation of Five Deschloroketamine Derivatives as Prerequisite for Wastewater-Based Epidemiology Screening.
Fabian Frankenfeld, Lea Wagmann, Markus R Meyer

Drug Test Anal· August 2025

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Renal Denervation Improves Uremic Cardiomyopathy in Rats With Chronic Kidney Disease.
Philipp Markwirth, Simina-Ramona Selejan, Mathias Hohl, Stefan J Schunk, Andreas Müller, Lea Wagmann

J Am Heart Assoc· August 2025

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A Comparative Study Using Reversed-Phase and Hydrophilic Interaction Liquid Chromatography to Investigate the In Vitro and In Vivo Metabolism of Five Selenium-Containing Cathinone Derivatives.
Lea Wagmann, Jana H Schmitt, Tanja M Gampfer, Simon D Brandt, Kenneth Scott

Metabolites· July 2025

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Metabolic fate of drugs of abuse and new psychoactive substances: A pilot study on a novel workflow using a zebrafish embryo model combined with human microdosing.
Simon K Wellenberg, Tanja M Gampfer, Lea Wagmann, Philip Schippers, Jennifer Herrmann

Br J Clin Pharmacol· June 2025

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Assessing phototoxic drug properties of hydrochlorothiazide using human skin biopsies.
Mathias Hohl, Felix Götzinger, Simone Jäger, Lea Wagmann, Mert Tokcan

Commun Biol· May 2025

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Toxicokinetics and analytical toxicology of the phenmetrazine-derived new psychoactive substance 3,4-methylenedioxyphenmetrazine studied by means of in vitro systems.
Matthias D Kroesen, Tanja M Gampfer, Lea Wagmann, Markus R Meyer

Arch Toxicol· April 2025

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Quantitative analysis of drugs of abuse and cognitive enhancers in influent wastewater by means of two chromatographic methods.
Fabian Frankenfeld, Lea Wagmann, Cathy M Jacobs, Markus R Meyer

Drug Test Anal· September 2024

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Studying drug excretion into exhaled breath aerosol - A workflow based on an impaction sampling device and LC-HRMS/MS analysis.
Juel Maalouli Schaar, Michael Kunz, Lea Wagmann, Olof Beck, Felix Mahfoud

Anal Chim Acta· September 2024

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Rapid analysis of amatoxins in human urine by means of affinity column chromatography and liquid chromatography-high-resolution tandem mass spectrometry.
Aline C Vollmer, Claudia Fecher-Trost, Candace S Bever, Christina C Tam, Lea Wagmann

Sci Rep· September 2024

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Metabolism and cytotoxicity studies of the two hallucinogens 1cP-LSD and 4-AcO-DET in human liver and zebrafish larvae models using LC-HRMS/MS and a high-content screening assay.
Tanja M Gampfer, Victoria Schütz, Philip Schippers, Sari Rasheed, Jonas Baumann, Lea Wagmann

J Pharm Biomed Anal· August 2024

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Prevalence of Drugs of Abuse and Cognitive Enhancer Consumption Monitored in Grab Samples and Composite Wastewater via Orbitrap Mass Spectrometry Analysis.
Fabian Frankenfeld, Lea Wagmann, Cathy M Jacobs, Markus R Meyer

Molecules· August 2024

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Impact of four different extraction methods and three different reconstitution solvents on the untargeted metabolomics analysis of human and rat urine samples.
Selina Hemmer, Sascha K Manier, Lea Wagmann, Markus R Meyer

J Chromatogr A· June 2024

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Towards clinical adherence monitoring of oral endocrine breast cancer therapies by LC-HRMS-method development, validation, comparison of four sample matrices, and proof of concept.
Cathy M Jacobs, Julia C Radosa, Lea Wagmann, Julia S M Zimmermann, Askin C Kaya

Anal Bioanal Chem· May 2024

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In Vivo and In Vitro Metabolic Fate and Urinary Detectability of Five Deschloroketamine Derivatives Studied by Means of Hyphenated Mass Spectrometry.
Fabian Frankenfeld, Lea Wagmann, Anush Abelian, Jason Wallach, Adeboye Adejare

Metabolites· May 2024

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Comparison of reversed-phase, hydrophilic interaction, and porous graphitic carbon chromatography columns for an untargeted toxicometabolomics study in pooled human liver microsomes, rat urine, and rat plasma.
Selina Hemmer, Sascha K Manier, Lea Wagmann, Markus R Meyer

Metabolomics· April 2024

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Sample Matrices for Mass Spectrometry-Based Adherence Monitoring: A Systematic Critical Review.
Cathy M Jacobs, Lea Wagmann, Markus R Meyer

Ther Drug Monit· February 2024

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Evaluation of extraction methods for untargeted metabolomic studies for future applications in zebrafish larvae infection models.
Philip Schippers, Sari Rasheed, Yu Mi Park, Timo Risch, Lea Wagmann

Sci Rep· May 2023

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