Publications by authors named "Lecia Sequist"

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Eradicating Drug-tolerant Persister Cells in EGFR-Mutated Non-Small Cell Lung Cancer by Targeting TROP2 with CAR-T Cellular Therapy.
Simon Baldacci, Elliott J Brea, Francesco Facchinetti, Zhaorong Li, Kenneth Ngo, Lecia V Sequist

Cancer Discov· November 2025

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Lung Cancer Screening Saves Lives, but Could Save So Many More.
Alexandra L Potter, Lecia V Sequist, Chi-Fu Jeffrey Yang

JAMA· November 2025

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Blended palliative and survivorship care intervention (POISE) for patients with metastatic oncogene-driven non-small cell lung cancer: study protocol for a pilot randomised controlled trial.
Heather A Richard, Roshni Sarathy, Dustin J Rabideau, Jill Feldman, Leslie Cartagena, Lecia V Sequist

BMJ Open· August 2025

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Multimodal profiling of proinflammatory protease activity identifies caspase-1 as a target for lung cancer interception.
Cathy S Wang, Qian Zhong, Shih-Ting Wang, Carmen Martin-Alonso, Sofia Neaher, Lecia V Sequist

bioRxiv· July 2025

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Significance of Image Reconstruction Parameters for Future Lung Cancer Risk Prediction Using Low-Dose Chest Computed Tomography and the Open-Access Sybil Algorithm.
Judit Simon, Peter Mikhael, Alexander Graur, Allison E B Chang, Steven J Skates, Lecia V Sequist

Invest Radiol· May 2025

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Preventive Health Care Use Among Adults Eligible for Lung Cancer Screening in the US.
Alexandra L Potter, Soneesh Kothagundla, Chinmay Haridas, Allison E B Chang, Lecia V Sequist

JAMA· May 2025

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An ultrasensitive method for detection of cell-free RNA.
Monica C Nesselbush, Bogdan A Luca, Young-Jun Jeon, Isabel Jabara, Catherine B Meador, Lecia V Sequist

Nature· May 2025

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Therapy for Stage IV Non-Small Cell Lung Cancer Without Driver Alterations: ASCO Living Guideline, Version 2024.3.
Natasha B Leighl, Nofisat Ismaila, Greg Durm, Narjust Florez, Janet Freeman-Daily, Lecia Sequist

J Clin Oncol· April 2025

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Phase 2 Trial of Consolidative Stereotactic Body Radiation Therapy in Patients With Metastatic Oncogene-driven Non-small Cell Lung Carcinoma Treated With Tyrosine Kinase Inhibitors.
Florence K Keane, Beow Y Yeap, Melin J Khandekar, Jessica J Lin, Ibiayi Dagogo-Jack, Lecia V Sequist

Int J Radiat Oncol Biol Phys· March 2025

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GUK1 activation is a metabolic liability in lung cancer.
Jaime L Schneider, Kiran Kurmi, Yutong Dai, Ishita Dhiman, Shakchhi Joshi, Lecia V Sequist

Cell· March 2025

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Alectinib combined with cobimetinib in ALK-Rearranged lung Cancer: A phase IB study.
Ibiayi Dagogo-Jack, Alissa J Cooper, Bruce E Johnson, Justin F Gainor, Jessica J Lin, Lecia V Sequist

Lung Cancer· January 2025

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Tumor cell-based liquid biopsy using high-throughput microfluidic enrichment of entire leukapheresis product.
Avanish Mishra, Shih-Bo Huang, Taronish Dubash, Risa Burr, Jon F Edd, Lecia V Sequist

Nat Commun· January 2025

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Clinical Validation of a Cell-Free DNA Fragmentome Assay for Augmentation of Lung Cancer Early Detection.
Peter J Mazzone, Peter B Bach, Jacob Carey, Caitlin A Schonewolf, Katalin Bognar, Lecia V Sequist

Cancer Discov· November 2024

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Developmental mosaicism underlying EGFR-mutant lung cancer presenting with multiple primary tumors.
Risa Burr, Ignaty Leshchiner, Christina L Costantino, Martin Blohmer, Tilak Sundaresan, Lecia V Sequist

Nat Cancer· November 2024

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Capmatinib plus nazartinib in patients with EGFR-mutated non-small cell lung cancer.
Enriqueta Felip, Giulio Metro, Ross A Soo, Jürgen Wolf, Benjamin J Solomon, Lecia V Sequist

Eur J Cancer· September 2024

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Early Detection and Interception of Lung Cancer.
Allison E B Chang, Alexandra L Potter, Chi-Fu Jeffrey Yang, Lecia V Sequist

Hematol Oncol Clin North Am· August 2024

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The ASCENT Trial: a phase 2 study of induction and consolidation afatinib and chemoradiation with or without surgery in stage III EGFR-mutant NSCLC.
Allison E B Chang, Andrew J Piper-Vallillo, Raymond H Mak, Michael Lanuti, Alona Muzikansky, Lecia V Sequist

Oncologist· July 2024

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Pack-Year Smoking History: An Inadequate and Biased Measure to Determine Lung Cancer Screening Eligibility.
Alexandra L Potter, Nuo N Xu, Priyanka Senthil, Deepti Srinivasan, Hang Lee, Lecia V Sequist

J Clin Oncol· June 2024

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Therapy for Stage IV Non-Small Cell Lung Cancer With Driver Alterations: ASCO Living Guideline, Version 2023.3.
Ishmael A Jaiyesimi, Natasha B Leighl, Nofisat Ismaila, Krishna Alluri, Narjust Florez, Lecia Sequist

J Clin Oncol· April 2024

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Therapy for Stage IV Non-Small Cell Lung Cancer Without Driver Alterations: ASCO Living Guideline, Version 2023.3.
Ishmael A Jaiyesimi, Natasha B Leighl, Nofisat Ismaila, Krishna Alluri, Narjust Florez, Lecia Sequist

J Clin Oncol· April 2024

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Phase II Study of Osimertinib in Patients With Epidermal Growth Factor Receptor Mutations: Results From the NCI-MATCH ECOG-ACRIN (EAY131) Trial Subprotocol E.
Monica F Chen, Zihe Song, Helena A Yu, Lecia V Sequist, Christine M Lovly

JCO Precis Oncol· April 2024

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Tumor cell-based liquid biopsy using high-throughput microfluidic enrichment of entire leukapheresis product.
Avanish Mishra, Shih-Bo Huang, Taronish Dubash, Risa Burr, Jon F Edd, Lecia V Sequist

bioRxiv· March 2024

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Lung Cancer in Women: The Past, Present, and Future.
Narjust Florez, Lauren Kiel, Ivy Riano, Shruti Patel, Kathryn DeCarli, Lecia V Sequist

Clin Lung Cancer· January 2024

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Deploying blood-based cancer screening.
Douglas S Micalizzi, Lecia V Sequist, Daniel A Haber

Science· January 2024

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Twenty-year Progress in Lung Cancer Screening: A Marathon, Not a Sprint.
Lecia V Sequist, Coral Olazagasti

Radiology· November 2023

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