Publications by authors named "Ledu Zhou"

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China Liver Cancer Guidelines for the Diagnosis and Treatment of Hepatocellular Carcinoma (2024 Edition).
Jian Zhou, Huichuan Sun, Zheng Wang, Wenming Cong, Mengsu Zeng, Weiping Zhou, Ledu Zhou

Liver Cancer· December 2025

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USP2-mediated PPARγ stabilization promotes hepatocellular carcinoma progression and M2 macrophage polarization via oleic acid.
Jing Cao, Kui Chen, Kuan Hu, Xingyu Mi, Yilin Pan, Ledu Zhou

J Immunother Cancer· November 2025

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Comparison of Efficacy between Lenvatinib and Bevacizumab in Combination of Immune Checkpoint Inhibitor and Interventional Triple Therapy in Chinese Advanced Hepatocellular Carcinoma: The CLEAP 2302 Study.
Zhaolong Pan, Dongming Liu, Junbo Cao, Linlin Fu, Xihao Zhang, Ledu Zhou

Liver Cancer· October 2025

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The impact of proximity to major central hepatic vasculature on perioperative outcomes and size-based risk stratification in hepatic hemangioma surgery.
Yulin Xie, Hanrui Yang, Shiqi Lu, Guo Long, Xingyu Mi, Ledu Zhou

PLoS One· September 2025

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Toripalimab plus bevacizumab versus sorafenib as first-line treatment for advanced hepatocellular carcinoma (HEPATORCH): a randomised, open-label, phase 3 trial.
Yinghong Shi, Guohong Han, Jian Zhou, Xuetao Shi, Weidong Jia, Ledu Zhou, Fuxiang Zhou

Lancet Gastroenterol Hepatol· July 2025

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Deubiquitylating Enzymes in Hepatocellular Carcinoma.
Xingyu Mi, Qingfeng Li, Guo Long, Yilin Pan, Yulin Xie, Ledu Zhou

Int J Biol Sci· July 2025

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Efficacy and safety of combined targeted therapy and immunotherapy versus targeted monotherapy in older patients with uHCC.
Yu Li, Jian-Hong Zhong, Xiao-Dong Zhu, Chuang-Ye Han, Jia-Bei Wang, Le-Du Zhou

Front Oncol· April 2025

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Postoperative recurrent jaundice and fever: A deceptive case caused by hemobilia.
Hanrui Yang, Kuan Hu, Ledu Zhou

Int J Surg Case Rep· July 2024

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USP8 promotes the tumorigenesis of intrahepatic cholangiocarcinoma via stabilizing OGT.
Guo Long, Dong Wang, Jianing Tang, Kuan Hu, Ledu Zhou

Cancer Cell Int· July 2024

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Prognoses of Patients Treated With Surgical Therapy Versus Continuation of Local-Plus-Systemic Therapy Following Successful Down-Staging of Intermediate-Advanced Hepatocellular Carcinoma: A Multicenter Real-World Study.
Jianwei Liu, Xiaodong Zhu, Yangxun Pan, Jianhong Zhong, Renan Jin, Ledu Zhou

Oncologist· April 2024

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UCHL3 inhibits ferroptosis by stabilizing β-catenin and maintains stem-like properties of hepatocellular carcinoma cells.
Guo Long, Zheyu Wu, Dong Wang, Xingyu Mi, Kuan Hu, Ledu Zhou

Free Radic Biol Med· February 2024

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ATR-dependent ubiquitin-specific protease 20 phosphorylation confers oxaliplatin and ferroptosis resistance.
Jianing Tang, Guo Long, Desheng Xiao, Shuang Liu, Liang Xiao, Ledu Zhou

MedComm (2020)· December 2023

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Targeting USP8 Inhibits O-GlcNAcylation of SLC7A11 to Promote Ferroptosis of Hepatocellular Carcinoma via Stabilization of OGT.
Jianing Tang, Guo Long, Kuan Hu, Desheng Xiao, Shuang Liu, Ledu Zhou

Adv Sci (Weinh)· November 2023

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Guidelines for the Diagnosis and Treatment of Primary Liver Cancer (2022 Edition).
Jian Zhou, Huichuan Sun, Zheng Wang, Wenming Cong, Mengsu Zeng, Weiping Zhou, Ledu Zhou

Liver Cancer· October 2023

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Systemic therapy with or without transcatheter intra-arterial therapies for unresectable hepatocellular carcinoma: a real-world, multi-center study.
Yangxun Pan, Xiaodong Zhu, Jianwei Liu, Jianhong Zhong, Wei Zhang, Ledu Zhou

Front Immunol· September 2023

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A robust panel based on genomic methylation sites for recurrence-free survival in early hepatocellular carcinoma.
Guo Long, Lihua Zhao, Biao Tang, Ledu Zhou, Xingyu Mi

Heliyon· September 2023

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The deubiquitinase EIF3H promotes hepatocellular carcinoma progression by stabilizing OGT and inhibiting ferroptosis.
Jianing Tang, Guo Long, Xuanxuan Li, Ledu Zhou, Yangying Zhou

Cell Commun Signal· August 2023

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Tumor Radiomic Features on Pretreatment MRI to Predict Response to Lenvatinib plus an Anti-PD-1 Antibody in Advanced Hepatocellular Carcinoma: A Multicenter Study.
Bin Xu, San-Yuan Dong, Xue-Li Bai, Tian-Qiang Song, Bo-Heng Zhang, Le-Du Zhou, Jian Zhou

Liver Cancer· August 2023

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USP8 positively regulates hepatocellular carcinoma tumorigenesis and confers ferroptosis resistance through β-catenin stabilization.
Jianing Tang, Guo Long, Liang Xiao, Ledu Zhou

Cell Death Dis· June 2023

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The deubiquitinating enzyme UCHL3 promotes anaplastic thyroid cancer progression and metastasis through Hippo signaling pathway.
Jianing Tang, Qian Yang, Chao Mao, Desheng Xiao, Shuang Liu, Ledu Zhou

Cell Death Differ· May 2023

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Radiographic and α-fetoprotein response predict pathologic complete response to immunotherapy plus a TKI in hepatocellular carcinoma: a multicenter study.
Cheng Huang, Xiao-Dong Zhu, Ying-Hao Shen, Bin Xu, Dong Wu, Le-Du Zhou, Jian Zhou

BMC Cancer· May 2023

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Spectrum of BRCA1 interacting helicase 1 aberrations and potential prognostic and therapeutic implication: a pan cancer analysis.
Guo Long, Kuan Hu, Xiaofang Zhang, Ledu Zhou, Juanni Li

Sci Rep· March 2023

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Chinese Expert Consensus on Immunotherapy for Hepatocellular Carcinoma (2021 Edition).
Yu Yang, Juxian Sun, Mengchao Wu, Wan Yee Lau, Shusen Zheng, Jie Zhou, Cuncai Zhou, Jun Zhou, Ledu Zhou, Xinmin Zhou

Liver Cancer· December 2022

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Identification and validation of a tyrosine metabolism-related prognostic prediction model and characterization of the tumor microenvironment infiltration in hepatocellular carcinoma.
Yangying Zhou, Xuanxuan Li, Guo Long, Yongguang Tao, Ledu Zhou

Front Immunol· November 2022

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Identification of senescence-related subtypes, establishment of a prognosis model, and characterization of a tumor microenvironment infiltration in breast cancer.
Yanling Zhou, Liang Xiao, Guo Long, Jing Cao, Shuang Liu, Ledu Zhou

Front Immunol· September 2022

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