Publications by authors named "Lee B Miles"

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Redundant and novel functions of scube genes during zebrafish development.
Quoc Duy Tran, Ivana Mirkovic, Lee B Miles, Joachim Berger, Alasdair J Wood

Dev Biol· December 2025

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Loss of the epithelial transcription factor grhl3 leads to variably penetrant developmental phenotypes in zebrafish.
Nishanthi Mathiyalagan, Travis K Johnson, Zachary Di Pastena, Jarrad N Fuller, Lee B Miles

Dev Dyn· October 2025

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HMGCS1 variants cause rigid spine syndrome amenable to mevalonic acid treatment in an animal model.
Lein N H Dofash, Lee B Miles, Yoshihiko Saito, Eloy Rivas, Vanessa Calcinotto

Brain· May 2025

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CRIMP: a CRISPR/Cas9 insertional mutagenesis protocol and toolkit.
Lee B Miles, Vanessa Calcinotto, Sara Oveissi, Rita J Serrano, Carmen Sonntag

Nat Commun· June 2024

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Pathogenic variants disrupt sarcomere contractility resulting in hypo- and hypercontractile muscle disease.
Sandra Donkervoort, Martijn van de Locht, Dario Ronchi, Janine Reunert, Catriona A McLean, Lee B Miles

Sci Transl Med· April 2024

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Atrogin-1 promotes muscle homeostasis by regulating levels of endoplasmic reticulum chaperone BiP.
Avnika A Ruparelia, Margo Montandon, Jo Merriner, Cheng Huang, Siew Fen Lisa Wong, Lee B Miles

JCI Insight· March 2024

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Manipulation of Proteostasis Networks in Transgenic ZAAT Zebrafish via CRISPR-Cas9 Gene Editing.
Connie Fung, Lee B Miles, Robert J Bryson-Richardson, Phillip I Bird

Methods Mol Biol· December 2023

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Grhl3 promotes retention of epidermal cells under endocytic stress to maintain epidermal architecture in zebrafish.
Mandar Phatak, Shruti Kulkarni, Lee B Miles, Nazma Anjum, Sebastian Dworkin

PLoS Genet· September 2021

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Inactivation of in GRHL2-deficient mouse embryos rescues mid-gestation viability and secondary palate closure.
Marina R Carpinelli, Michael E de Vries, Alana Auden, Tariq Butt, Zihao Deng, Lee B Miles

Dis Model Mech· March 2020

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Meta-Analysis of Dependent Transcriptional Networks: A Roadmap for Identifying Novel Conserved Genetic Pathways.
Nishanthi Mathiyalagan, Lee B Miles, Peter J Anderson, Tomasz Wilanowski, Brian L Grills

Genes (Basel)· October 2019

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RGD inhibition of itgb1 ameliorates laminin-α2-deficient zebrafish fibre pathology.
Alasdair J Wood, Naomi Cohen, Veronica Joshi, Mei Li, Adam Costin, Lee B Miles

Hum Mol Genet· May 2019

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Mis-expression of grainyhead-like transcription factors in zebrafish leads to defects in enveloping layer (EVL) integrity, cellular morphogenesis and axial extension.
Lee B Miles, Charbel Darido, Jan Kaslin, Joan K Heath, Stephen M Jane

Sci Rep· December 2017

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Alternative splicing and start sites: Lessons from the Grainyhead-like family.
Lee B Miles, Sebastian Dworkin, Charbel Darido

Dev Biol· September 2017

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A role for planar cell polarity during early endoderm morphogenesis.
Lee B Miles, Takamasa Mizoguchi, Yutaka Kikuchi, Heather Verkade

Biol Open· May 2017

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Haematopoietic stem cell induction by somite-derived endothelial cells controlled by meox1.
Phong Dang Nguyen, Georgina Elizabeth Hollway, Carmen Sonntag, Lee Barry Miles, Thomas Edward Hall

Nature· August 2014

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TA-cloning vectors for rapid and cheap cloning of zebrafish transgenesis constructs.
Lee B Miles, Heather Verkade

Zebrafish· June 2014

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