Publications by authors named "Lee Chaves"

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Nicotinamide riboside supplementation restores microglial health and improves cognition in aged male mice.
Ramkumar Thiyagarajan, Rupadevi Muthaiah, Bhavana Sreevelu, Owen P Treanor, Yonas Redae, Lee D Chaves

Geroscience· November 2025

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High-Intensity Interval Exercise Drives Vitamin D Receptor Expression in Skeletal Muscle via Recruitment of Non-Parenchymal Cells, Not Upregulation in Muscle Fibers.
Kenneth Ladd Seldeen, Ni Wang, Rupadevi Muthaiah, Owen Paul Treanor, Anna Leigh Davis, Lee Daniel Chaves

Nutrients· November 2025

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The first endovascular rat glioma model for pre-clinical evaluation of intra-arterial therapeutics.
Jaims Lim, Ammad A Baig, Brianna M Donnelly, Lee D Chaves, Suyog U Pol

Interv Neuroradiol· August 2025

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Inhalational Delivery of glucan-chitosan-poly(lactic co-glycolic) acid Nanoparticles Enhance Alveolar Macrophage Rifampin Concentrations for the Treatment of Tuberculosis.
Hilliard L Kutscher, Maria Tamblin, Shanta Karki, Lee Chaves, Marissa Baird

Adv Ther (Weinh)· April 2025

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CHRFAM7A diversifies human immune adaption through Ca signalling and actin cytoskeleton reorganization.
Kinga Szigeti, Ivanna Ihnatovych, Emily Notari, Ryu P Dorn, Ivan Maly, Lee Chaves

EBioMedicine· May 2024

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Nuclear Factor I A and Nuclear Factor I B Are Jointly Required for Mouse Postnatal Neural Stem Cell Self-Renewal.
Christine E Campbell, Karstin Webber, Jonathan E Bard, Lee D Chaves, Jason M Osinski

Stem Cells Dev· April 2024

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Multimodal exercise training to reduce frailty in people with multiple sclerosis: study protocol for a pilot randomized controlled trial.
Tobia Zanotto, Danya Pradeep Kumar, Abbas Tabatabaei, Sharon G Lynch, Jianghua He, Lee Chaves

Pilot Feasibility Stud· April 2024

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Gene expression profiles of ischemic stroke clots retrieved by mechanical thrombectomy are associated with disease etiology.
Vincent M Tutino, Sarah Fricano, Aichi Chien, Tatsat R Patel, Andre Monteiro, Lee D Chaves

J Neurointerv Surg· September 2023

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An immunoregulator nanomedicine approach for the treatment of tuberculosis.
Luona Yang, Lee Chaves, Hilliard L Kutscher, Shanta Karki, Maria Tamblin

Front Bioeng Biotechnol· May 2023

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Defining the Intravital Renal Disposition of Fluorescence-Quenched Exenatide.
Mark A Bryniarski, Ruben M Sandoval, Donna M Ruszaj, John Fraser-McArthur, Benjamin M Yee, Lee D Chaves

Mol Pharm· February 2023

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Profiling of Circulating Gene Expression Reveals Molecular Signatures Associated with Intracranial Aneurysm Rupture Risk.
Kerry E Poppenberg, Aichi Chien, Briana A Santo, Lee Chaves, Sricharan S Veeturi

Mol Diagn Ther· January 2023

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Correction to: Mitochondrial Dynamics in SARS‑COV2 Spike Protein Treated Human Microglia: Implications for Neuro‑COVID.
Erin Clough, Joseph Inigo, Dhyan Chandra, Lee Chaves, Jessica L Reynolds

J Neuroimmune Pharmacol· December 2022

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Mitochondrial Dynamics in SARS-COV2 Spike Protein Treated Human Microglia: Implications for Neuro-COVID.
Erin Clough, Joseph Inigo, Dhyan Chandra, Lee Chaves, Jessica L Reynolds

J Neuroimmune Pharmacol· December 2021

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RNA Sequencing Data from Human Intracranial Aneurysm Tissue Reveals a Complex Inflammatory Environment Associated with Rupture.
Vincent M Tutino, Haley R Zebraski, Hamidreza Rajabzadeh-Oghaz, Lee Chaves, Adam A Dmytriw

Mol Diagn Ther· November 2021

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Isolation of RNA from Acute Ischemic Stroke Clots Retrieved by Mechanical Thrombectomy.
Vincent M Tutino, Sarah Fricano, Kirsten Frauens, Tatsat R Patel, Andre Monteiro, Lee Chaves

Genes (Basel)· October 2021

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Unconjugated p-cresol activates macrophage macropinocytosis leading to increased LDL uptake.
Lee D Chaves, Sham Abyad, Amanda M Honan, Mark A Bryniarski, Daniel I McSkimming

JCI Insight· June 2021

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Immunoglobulin G Is a Novel Substrate for the Endocytic Protein Megalin.
Mark A Bryniarski, Bei Zhao, Lee D Chaves, Jakob Hauge Mikkelsen, Benjamin M Yee

AAPS J· March 2021

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Hybrid Curdlan Poly(γ -Glutamic Acid) Nanoassembly for Immune Modulation in Macrophage.
Jeongyun Heo, Thomas A Sobiech, Hilliard L Kutscher, Lee Chaves, Dinesh K Sukumaran

Macromol Biosci· January 2021

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Classification models using circulating neutrophil transcripts can detect unruptured intracranial aneurysm.
Kerry E Poppenberg, Vincent M Tutino, Lu Li, Muhammad Waqas, Armond June, Lee Chaves

J Transl Med· October 2020

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CHRFAM7A: A human specific fusion gene, accounts for the translational gap for cholinergic strategies in Alzheimer's disease.
Kinga Szigeti, Ivanna Ihnatovych, Barbara Birkaya, Ziqiang Chen, Aya Ouf, Lee Chaves

EBioMedicine· September 2020

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Megalin-mediated albumin endocytosis in cultured murine mesangial cells.
Mark A Bryniarski, Benjamin M Yee, Lee D Chaves, Corrine M Stahura, Rabi Yacoub

Biochem Biophys Res Commun· August 2020

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Fecal microbiota analysis of polycystic kidney disease patients according to renal function: A pilot study.
Rabi Yacoub, Girish N Nadkarni, Daniel I McSkimming, Lee D Chaves, Sham Abyad

Exp Biol Med (Maywood)· April 2019

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iPSC model of CHRFAM7A effect on α7 nicotinic acetylcholine receptor function in the human context.
Ivanna Ihnatovych, Tapan K Nayak, Aya Ouf, Norbert Sule, Barbara Birkaya, Lee Chaves

Transl Psychiatry· February 2019

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Increased megalin expression in early type 2 diabetes: role of insulin-signaling pathways.
Mark A Bryniarski, Benjamin M Yee, Irum Jaffri, Lee D Chaves, Jin Ah Yu

Am J Physiol Renal Physiol· November 2018

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Chronic kidney disease, uremic milieu, and its effects on gut bacterial microbiota dysbiosis.
Lee D Chaves, Daniel I McSkimming, Mark A Bryniarski, Amanda M Honan, Sham Abyad

Am J Physiol Renal Physiol· September 2018

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