Publications by authors named "Lee D Jennings"

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Acylguanidine inhibitors of beta-secretase: optimization of the pyrrole ring substituents extending into the S1 and S3 substrate binding pockets.
Derek C Cole, Joseph R Stock, Rajiv Chopra, Rebecca Cowling, John W Ellingboe, Lee D Jennings

Bioorg Med Chem Lett· February 2008

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Acylguanidine inhibitors of beta-secretase: optimization of the pyrrole ring substituents extending into the S1' substrate binding pocket.
Lee D Jennings, Derek C Cole, Joseph R Stock, Mohani N Sukhdeo, John W Ellingboe

Bioorg Med Chem Lett· January 2008

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Discovery of novel inhibitors of the ZipA/FtsZ complex by NMR fragment screening coupled with structure-based design.
Désirée H H Tsao, Alan G Sutherland, Lee D Jennings, Yuanhong Li, Thomas S Rush

Bioorg Med Chem· December 2006

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Acylguanidines as small-molecule beta-secretase inhibitors.
Derek C Cole, Eric S Manas, Joseph R Stock, Jeffrey S Condon, Lee D Jennings

J Med Chem· October 2006

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Parallel synthesis and biological evaluation of 5,6,7,8-tetrahydrobenzothieno[2,3-d]pyrimidin-4(3H)-one cytotoxic agents selective for p21-deficient cells.
Lee D Jennings, Scott L Kincaid, Yanong D Wang, Girija Krishnamurthy, Carl F Beyer

Bioorg Med Chem Lett· November 2005

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Combinatorial synthesis of substituted 3-(2-indolyl)piperidines and 2-phenyl indoles as inhibitors of ZipA-FtsZ interaction.
Lee D Jennings, Kenneth W Foreman, Thomas S Rush, Desiree H H Tsao, Lidia Mosyak

Bioorg Med Chem· October 2004

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Design and synthesis of indolo[2,3-a]quinolizin-7-one inhibitors of the ZipA-FtsZ interaction.
Lee D Jennings, Ken W Foreman, Thomas S Rush, Desiree H H Tsao, Lidia Mosyak

Bioorg Med Chem Lett· March 2004

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