Publications by authors named "Lee Farrand"

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C‑terminal HSP90 inhibitor NCT‑58 impairs the cancer stem‑like phenotype and enhances chemotherapy efficacy in TNBC.
Eunsun Jung, Yoon-Jae Kim, Kyoungmin Lee, Seojin Jang, Soeun Park, Lee Farrand

Oncol Rep· January 2026

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Pitavastatin is a novel Mcl-1 inhibitor that overcomes paclitaxel resistance in triple-negative breast cancer.
Dongmi Ko, Soeun Park, Minsu Park, Seongjae Kim, Jung Min Park, Lee Farrand

Exp Hematol Oncol· October 2025

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FDA regulatory considerations for oncology drug development.
Hanlim Moon, Dae Young Zang, Min-Hee Ryu, YeonSook Seo, Bitna Oh, Lee Farrand

Pharmacol Res Perspect· August 2024

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The HSP90 inhibitor HVH-2930 exhibits potent efficacy against trastuzumab-resistant HER2-positive breast cancer.
Minsu Park, Eunsun Jung, Jung Min Park, Soeun Park, Dongmi Ko, Lee Farrand

Theranostics· April 2024

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Suppression of TNBC metastasis by doxazosin, a novel dual inhibitor of c-MET/EGFR.
Seongjae Kim, Jung Min Park, Soeun Park, Eunsun Jung, Dongmi Ko, Lee Farrand

J Exp Clin Cancer Res· November 2023

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Ebastine impairs metastatic spread in triple-negative breast cancer by targeting focal adhesion kinase.
Juyeon Seo, Minsu Park, Dongmi Ko, Seongjae Kim, Jung Min Park, Lee Farrand

Cell Mol Life Sci· April 2023

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β-Escin overcomes trastuzumab resistance in HER2-positive breast cancer by targeting cancer stem-like features.
Soeun Park, Jung Min Park, Minsu Park, Dongmi Ko, Seongjae Kim, Lee Farrand

Cancer Cell Int· September 2022

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A novel HSP90 inhibitor SL-145 suppresses metastatic triple-negative breast cancer without triggering the heat shock response.
Ji Young Kim, Tae-Min Cho, Jung Min Park, Soeun Park, Minsu Park, Lee Farrand

Oncogene· June 2022

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The C-terminal HSP90 inhibitor NCT-58 kills trastuzumab-resistant breast cancer stem-like cells.
Soeun Park, Yoon-Jae Kim, Jung Min Park, Minsu Park, Kee Dal Nam, Lee Farrand

Cell Death Discov· November 2021

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A novel HSP90 inhibitor targeting the C-terminal domain attenuates trastuzumab resistance in HER2-positive breast cancer.
Jung Min Park, Yoon-Jae Kim, Soeun Park, Minsu Park, Lee Farrand

Mol Cancer· November 2020

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C-terminal HSP90 inhibitor L80 elicits anti-metastatic effects in triple-negative breast cancer via STAT3 inhibition.
Tae-Min Cho, Ji Young Kim, Yoon-Jae Kim, Daeil Sung, Eunhye Oh, Lee Farrand

Cancer Lett· April 2019

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Flubendazole elicits anti-metastatic effects in triple-negative breast cancer via STAT3 inhibition.
Eunhye Oh, Yoon-Jae Kim, Hyunsook An, Daeil Sung, Tae-Min Cho, Lee Farrand

Int J Cancer· October 2018

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Flubendazole overcomes trastuzumab resistance by targeting cancer stem-like properties and HER2 signaling in HER2-positive breast cancer.
Yoon-Jae Kim, Daeil Sung, Eunhye Oh, Youngkwan Cho, Tae-Min Cho, Lee Farrand

Cancer Lett· January 2018

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Induction of Synthetic Lethality by Natural Compounds Targeting Cancer Signaling.
Lee Farrand, Sanguine Byun

Curr Pharm Des· November 2017

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Sulforaphene suppresses growth of colon cancer-derived tumors via induction of glutathione depletion and microtubule depolymerization.
Sanguine Byun, Seung Ho Shin, Jiman Park, Semi Lim, Eunjung Lee, Lee Farrand

Mol Nutr Food Res· May 2016

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The retinoic acid derivative, ABPN, inhibits pancreatic cancer through induction of Nrdp1.
Sanguine Byun, Seung Ho Shin, Eunjung Lee, Jihoon Lee, Sung-Young Lee, Lee Farrand

Carcinogenesis· December 2015

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Identification of a Dual Inhibitor of Janus Kinase 2 (JAK2) and p70 Ribosomal S6 Kinase1 (S6K1) Pathways.
Sanguine Byun, Semi Lim, Ji Young Mun, Ki Hyun Kim, Timothy R Ramadhar, Lee Farrand

J Biol Chem· September 2015

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Phytochemicals: a multitargeted approach to gynecologic cancer therapy.
Lee Farrand, Se-Woong Oh, Yong Sang Song, Benjamin K Tsang

Biomed Res Int· March 2015

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The mTORC2 component rictor contributes to cisplatin resistance in human ovarian cancer cells.
Akechai Im-aram, Lee Farrand, Seung-Min Bae, Gwonhwa Song, Yong Sang Song

PLoS One· July 2014

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An improved quantitative approach for the assessment of mitochondrial fragmentation in chemoresistant ovarian cancer cells.
Lee Farrand, Ji Young Kim, Akechai Im-Aram, Jeong-Yong Suh, Hyong Joo Lee

PLoS One· June 2014

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The diarylheptanoid hirsutenone sensitizes chemoresistant ovarian cancer cells to cisplatin via modulation of apoptosis-inducing factor and X-linked inhibitor of apoptosis.
Lee Farrand, Ji Young Kim, Sanguine Byun, Akechai Im-aram, Jihoon Lee

J Biol Chem· January 2014

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Piceatannol enhances cisplatin sensitivity in ovarian cancer via modulation of p53, X-linked inhibitor of apoptosis protein (XIAP), and mitochondrial fission.
Lee Farrand, Sanguine Byun, Ji Young Kim, Akechai Im-Aram, Jihoon Lee

J Biol Chem· August 2013

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USP8 is a novel target for overcoming gefitinib resistance in lung cancer.
Sanguine Byun, Sung-Young Lee, Jihoon Lee, Chul-Ho Jeong, Lee Farrand

Clin Cancer Res· July 2013

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Molecular determinants of ovarian cancer chemoresistance: new insights into an old conundrum.
Ahmed Y Ali, Lee Farrand, Ji Young Kim, Sanguine Byun, Jeong-Yong Suh

Ann N Y Acad Sci· October 2012

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