Publications by authors named "Lee Frego"

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GPR180 is a new member of the Golgi-dynamics domain seven-transmembrane helix protein family.
Sarah-Ana Mitrovic, Chamalee Demalgiriya-Gamage, Lisa-Maria Winter, Tobias Kiechle, Rebecca Ebenhoch, Lee Frego

Commun Biol· November 2024

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Effect of the ADCC-Modulating Mutations and the Selection of Human IgG Isotypes on Physicochemical Properties of Fc.
Helen Haixia Wu, Maureen Crames, Yangjie Wei, Dongmei Liu, Kristina Gueneva-Boucheva, Lee Frego

J Pharm Sci· September 2022

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Combination of two novel blocking antibodies, anti-PD-1 antibody ezabenlimab (BI 754091) and anti-LAG-3 antibody BI 754111, leads to increased immune cell responses.
Markus Zettl, Melanie Wurm, Otmar Schaaf, Sven Mostböck, Iñigo Tirapu, Lee Frego

Oncoimmunology· June 2022

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An optimally designed anti-human CD40 antibody with potent B cell suppression for the treatment of autoimmune diseases.
Helen Haixia Wu, Kerry-Leigh Ralph, Eliud Sepuldeva, Gale Hansen, Hua Li, Lee Frego

Int J Pharm· November 2021

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Crystal structure and receptor-interacting residues of MYDGF - a protein mediating ischemic tissue repair.
Rebecca Ebenhoch, Abbas Akhdar, Marc R Reboll, Mortimer Korf-Klingebiel, Priyanka Gupta, Lee Frego

Nat Commun· November 2019

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Design and characterization of Zweimab and Doppelmab, high affinity dual antagonistic anti-TSLP/IL13 bispecific antibodies.
Sathyadevi Venkataramani, Sarah Low, Bernd Weigle, Darrin Dutcher, Kavita Jerath, Lee Frego

Biochem Biophys Res Commun· September 2018

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Generation and functional characterization of anti-human and anti-mouse IL-36R antagonist monoclonal antibodies.
Rajkumar Ganesan, Ernest L Raymond, Detlev Mennerich, Joseph R Woska, Gary Caviness, Lee Frego

MAbs· October 2017

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Efficient Qualitative and Quantitative Determination of Antigen-induced Immune Responses.
Danlin Yang, Lee Frego, Marcio Lasaro, Kristopher Truncali, Rachel Kroe-Barrett

J Biol Chem· July 2016

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Selective targeting of the IL23 pathway: Generation and characterization of a novel high-affinity humanized anti-IL23A antibody.
Sanjaya Singh, Rachel R Kroe-Barrett, Keith A Canada, Xiang Zhu, Eliud Sepulveda, Lee E Frego

MAbs· March 2016

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The determination of high-affinity protein/inhibitor binding constants by electrospray ionization hydrogen/deuterium exchange mass spectrometry.
Lee Frego, Elda Gautschi, Leslie Martin, Walter Davidson

Rapid Commun Mass Spectrom· November 2007

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A steric antagonism of actin polymerization by a salmonella virulence protein.
S Mariana Margarit, Walter Davidson, Lee Frego, C Erec Stebbins

Structure· August 2006

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Conformational changes of the glucocorticoid receptor ligand binding domain induced by ligand and cofactor binding, and the location of cofactor binding sites determined by hydrogen/deuterium exchange mass spectrometry.
Lee Frego, Walter Davidson

Protein Sci· April 2006

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Discovery and characterization of a substrate selective p38alpha inhibitor.
Walter Davidson, Lee Frego, Gregory W Peet, Rachel R Kroe, Mark E Labadia

Biochemistry· September 2004

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Catalysis and function of the p38 alpha.MK2a signaling complex.
Susan M Lukas, Rachel R Kroe, Jessi Wildeson, Gregory W Peet, Lee Frego

Biochemistry· August 2004

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Characterization of the binding site for inhibitors of the HPV11 E1-E2 protein interaction on the E2 transactivation domain by photoaffinity labeling and mass spectrometry.
Walter Davidson, Graham A McGibbon, Peter W White, Christiane Yoakim, Jerry L Hopkins, Lee Frego

Anal Chem· April 2004

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Micro-high-performance liquid chromatography/Fourier transform mass spectrometry with electron-capture dissociation for the analysis of protein enzymatic digests.
Walter Davidson, Lee Frego

Rapid Commun Mass Spectrom· June 2002

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