Publications by authors named "Lee Zou"

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ZNF280A links DNA double-strand break repair to human 22q11.2 distal deletion syndrome.
Thomas L Clarke, Hyo Min Cho, Ilaria Ceppi, Boya Gao, Tribhuwan Yadav, Lee Zou

Nat Cell Biol· June 2025

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Gap resection matters in BRCA mutant cancer.
Lee Zou

Genes Dev· May 2025

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Building an integrated view of R-loops, transcription, and chromatin.
Yingying Meng, Lee Zou

DNA Repair (Amst)· May 2025

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BRCA1-A and LIG4 complexes mediate ecDNA biogenesis and cancer drug resistance.
Oliver W Chung, Shun Yao, Fu Yang, Ling Wang, Christian Cerda-Smith, Lee Zou

bioRxiv· February 2025

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A Translational Study of the ATR Inhibitor Berzosertib as Monotherapy in Four Molecularly Defined Cohorts of Advanced Solid Tumors.
Gregory M Cote, Bose S Kochupurakkal, Khanh Do, Andrea Bullock, Michael L Cheng, Lee Zou

Clin Cancer Res· January 2025

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Inhibition of Androgen Receptor Exposes Replication Stress Vulnerability in Prostate Cancer.
Carly S Williams, Xin Li, Hongjun Jang, Jay Ramanlal Anand, Won Young Lim, Lee Zou

bioRxiv· October 2024

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Regulation, functional impact, and therapeutic targeting of APOBEC3A in cancer.
Ajinkya S Kawale, Lee Zou

DNA Repair (Amst)· September 2024

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A RAD18-UBC13-PALB2-RNF168 axis mediates replication fork recovery in BRCA1-deficient cancer cells.
Emily Cybulla, Sierra Wallace, Alice Meroni, Jessica Jackson, Sumedha Agashe, Lee Zou

Nucleic Acids Res· August 2024

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EWS-WT1 fusion isoforms establish oncogenic programs and therapeutic vulnerabilities in desmoplastic small round cell tumors.
Gaylor Boulay, Liliane C Broye, Rui Dong, Sowmya Iyer, Rajendran Sanalkumar, Lee Zou

Nat Commun· August 2024

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BRCAness, DNA gaps, and gain and loss of PARP inhibitor-induced synthetic lethality.
Xin Li, Lee Zou

J Clin Invest· July 2024

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Unprocessed genomic uracil as a source of DNA replication stress in cancer cells.
Sneha Saxena, Christopher S Nabel, Turner W Seay, Parasvi S Patel, Ajinkya S Kawale, Lee Zou

Mol Cell· June 2024

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Author Correction: Meiotic protein SYCP2 confers resistance to DNA-damaging agents through R-loop-mediated DNA repair.
Yumin Wang, Boya Gao, Luyuan Zhang, Xudong Wang, Xiaolan Zhu, Lee Zou

Nat Commun· May 2024

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Meiotic protein SYCP2 confers resistance to DNA-damaging agents through R-loop-mediated DNA repair.
Yumin Wang, Boya Gao, Luyuan Zhang, Xudong Wang, Xiaolan Zhu, Lee Zou

Nat Commun· February 2024

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APOBEC3A induces DNA gaps through PRIMPOL and confers gap-associated therapeutic vulnerability.
Ajinkya S Kawale, Xiaojuan Ran, Parasvi S Patel, Sneha Saxena, Michael S Lawrence, Lee Zou

Sci Adv· January 2024

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ATR promotes clearance of damaged DNA and damaged cells by rupturing micronuclei.
Yoon Ki Joo, Elizabeth M Black, Isabelle Trier, Wisse Haakma, Lee Zou

Mol Cell· October 2023

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ATR inhibition induces synthetic lethality in mismatch repair-deficient cells and augments immunotherapy.
Mingchao Wang, Xiaojuan Ran, Wendy Leung, Ajinkya Kawale, Sneha Saxena, Lee Zou

Genes Dev· October 2023

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Heterochromatin-Dependent Replication Stress: A Lesson from IDH1/2 Mutants.
Lee Zou

Cancer Res· September 2023

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The RNA m5C modification in R-loops as an off switch of Alt-NHEJ.
Haibo Yang, Emily M Lachtara, Xiaojuan Ran, Jessica Hopkins, Parasvi S Patel, Lee Zou

Nat Commun· September 2023

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Therapy-induced APOBEC3A drives evolution of persistent cancer cells.
Hideko Isozaki, Ramin Sakhtemani, Ammal Abbasi, Naveed Nikpour, Marcello Stanzione, Lee Zou

Nature· August 2023

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An ATR-PrimPol pathway confers tolerance to oncogenic KRAS-induced and heterochromatin-associated replication stress.
Taichi Igarashi, Marianne Mazevet, Takaaki Yasuhara, Kimiyoshi Yano, Akifumi Mochizuki, Lee Zou

Nat Commun· August 2023

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A noncanonical enzymatic function of PIWIL4 maintains genomic integrity and leukemic growth in AML.
Shiva Bamezai, Alex Jose Pulikkottil, Tribhuwan Yadav, Naidu M Vegi, Julia Mueller, Lee Zou

Blood· July 2023

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ATR protects ongoing and newly assembled DNA replication forks through distinct mechanisms.
Wendy Leung, Antoine Simoneau, Sneha Saxena, Jessica Jackson, Parasvi S Patel, Lee Zou

Cell Rep· July 2023

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US "China initiatives" promote racial bias.
Shan-Lu Liu, Lishan Su, Kunxin Luo, Kai Li, Gang Chen, Lee Zou

Science· May 2023

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CRISPR screens reveal genetic determinants of PARP inhibitor sensitivity and resistance in prostate cancer.
Takuya Tsujino, Tomoaki Takai, Kunihiko Hinohara, Fu Gui, Takeshi Tsutsumi, Lee Zou

Nat Commun· January 2023

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TERRA and RAD51AP1 promote alternative lengthening of telomeres through an R- to D-loop switch.
Tribhuwan Yadav, Jia-Min Zhang, Jian Ouyang, Wendy Leung, Antoine Simoneau, Lee Zou

Mol Cell· November 2022

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