Publications by authors named "Leif Neitzel"

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Ogremorphin inhibits GPR68 mediated MUC5AC expression.
Leif R Neitzel, Hussain F Basrai, Charles C Hong, Charles H Williams

MicroPubl Biol· October 2025

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A novel transgenic reporter of extracellular acidification in zebrafish elucidates skeletal muscle T-tubule pH regulation.
Leif R Neitzel, Maya Silver, Aaron H Wasserman, Samantha Rea, Charles C Hong

Dev Dyn· September 2025

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Ferroptosis in the U87MG Human Glioblastoma Cell Line Induces Damage Associated Molecular Phenotypes.
Leif Neitzel, Samantha Rea, Jessica Cornell, Charles Williams, Charles Hong

MicroPubl Biol· July 2025

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The TRIP12 E3 ligase induces SWI/SNF component BRG1-β-catenin interaction to promote Wnt signaling.
Sara Kassel, Kai Yuan, Nawat Bunnag, Leif R Neitzel, Wenhui Lu

Nat Commun· June 2025

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Inhibition of GPR68 induces ferroptosis and radiosensitivity in diverse cancer cell types.
Leif R Neitzel, Daniela T Fuller, Jessica Cornell, Samantha Rea, Carolina de Aguiar Ferreira

Sci Rep· February 2025

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Inhibition of GPR68 kills glioblastoma in zebrafish xenograft models.
Leif R Neitzel, Daniela T Fuller, Charles H Williams, Charles C Hong

BMC Res Notes· August 2024

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GPR68-ATF4 signaling is a novel prosurvival pathway in glioblastoma activated by acidic extracellular microenvironment.
Charles H Williams, Leif R Neitzel, Jessica Cornell, Samantha Rea, Ian Mills

Exp Hematol Oncol· January 2024

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Proton Sensing GPCR's: The missing link to Warburg's Oncogenic Legacy?
Jessica Cornell, Samantha Rea, Leif R Neitzel, Charles H Williams, Charles C Hong

J Cancer Biol· January 2024

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The USP46 complex deubiquitylates LRP6 to promote Wnt/β-catenin signaling.
Victoria H Ng, Zachary Spencer, Leif R Neitzel, Anmada Nayak, Matthew A Loberg

Nat Commun· October 2023

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Impaired Reorganization of Centrosome Structure Underlies Human Infantile Dilated Cardiomyopathy.
Young Wook Chun, Matthew Miyamoto, Charles H Williams, Leif R Neitzel, Maya Silver-Isenstadt

Circulation· April 2023

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The Casein kinase 1α agonist pyrvinium attenuates Wnt-mediated CK1α degradation via interaction with the E3 ubiquitin ligase component Cereblon.
Chen Shen, Anmada Nayak, Leif R Neitzel, Fan Yang, Bin Li

J Biol Chem· August 2022

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The E3 ubiquitin ligase component, Cereblon, is an evolutionarily conserved regulator of Wnt signaling.
Chen Shen, Anmada Nayak, Leif R Neitzel, Amber A Adams, Maya Silver-Isenstadt

Nat Commun· September 2021

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The Role of Bone Morphogenetic Protein Signaling in Non-Alcoholic Fatty Liver Disease.
Timothy E Thayer, Christian L Lino Cardenas, Trejeeve Martyn, Christopher J Nicholson, Lisa Traeger, Leif R Neitzel

Sci Rep· June 2020

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Developmental regulation of Wnt signaling by Nagk and the UDP-GlcNAc salvage pathway.
Leif R Neitzel, Zachary T Spencer, Anmada Nayak, Christopher S Cselenyi, Hassina Benchabane

Mech Dev· April 2019

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Correction: Characterization of a  null allele in  (doi:10.1242/bio.035394).
Leif Neitzel, Matthew Broadus, Nailing Zhang, Leah Sawyer, Heather Wallace

Biol Open· August 2018

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Characterization of a null allele in .
Leif R Neitzel, Matthew R Broadus, Nailing Zhang, Leah Sawyer, Heather A Wallace

Biol Open· July 2018

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Phosphorylation of XIAP at threonine 180 controls its activity in Wnt signaling.
Victoria H Ng, Brian I Hang, Leah M Sawyer, Leif R Neitzel, Emily E Crispi

J Cell Sci· May 2018

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Differential abundance of CK1α provides selectivity for pharmacological CK1α activators to target WNT-dependent tumors.
Bin Li, Darren Orton, Leif R Neitzel, Luisana Astudillo, Chen Shen

Sci Signal· June 2017

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The MAPK Pathway Regulates Intrinsic Resistance to BET Inhibitors in Colorectal Cancer.
Yufang Ma, Lihong Wang, Leif R Neitzel, Sudan N Loganathan, Nan Tang

Clin Cancer Res· April 2017

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Comparative genetic screens in human cells reveal new regulatory mechanisms in WNT signaling.
Andres M Lebensohn, Ramin Dubey, Leif R Neitzel, Ofelia Tacchelly-Benites, Eungi Yang

Elife· December 2016

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The Small Molecule IMR-1 Inhibits the Notch Transcriptional Activation Complex to Suppress Tumorigenesis.
Luisana Astudillo, Thiago G Da Silva, Zhiqiang Wang, Xiaoqing Han, Ke Jin, Leif R Neitzel

Cancer Res· June 2016

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Identification of a Paralog-Specific Notch1 Intracellular Domain Degron.
Matthew R Broadus, Tony W Chen, Leif R Neitzel, Victoria H Ng, Jeanne N Jodoin

Cell Rep· May 2016

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Kabuki syndrome genes KMT2D and KDM6A: functional analyses demonstrate critical roles in craniofacial, heart and brain development.
Peter M Van Laarhoven, Leif R Neitzel, Anita M Quintana, Elizabeth A Geiger, Elaine H Zackai

Hum Mol Genet· August 2015

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The Drosophila MCPH1-B isoform is a substrate of the APCCdh1 E3 ubiquitin ligase complex.
Sarah G Hainline, Jamie L Rickmyre, Leif R Neitzel, Laura A Lee, Ethan Lee

Biol Open· June 2014

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