Publications by authors named "Leilei Fu"

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Decoding protein kinases in autophagy with small-molecule modulators for cancer therapy.
Mengqiao Chen, Xiangyu Fu, Huiping Wang, Xinyi Qi, Leilei Fu

Drug Discov Today· November 2025

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Influence of blood transfusion on postoperative inflammation, stress markers, and prognosis in patients with gastric cancer.
Yan-Qin Chen, Jian-Hui Chen, Yi-Xin Zhang, Lei-Lei Fu, Xiao-Shuang Luo

World J Gastroenterol· October 2025

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Suppression of LIF in tumor-associated macrophages contributing to the PD-1/PD-L1 blockade in hepatocellular carcinoma.
Shuangshuang Yin, Yanming Luo, Miaomiao Jiang, Lifeng Han, Sibao Chen, Leilei Fu

J Pharm Anal· October 2025

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Funiculosins B-F, Five Undescribed Pyridinone Derivatives Isolated From the Fungus Talaromyces cecidicola J-4.
Leilei Fu, Jiayu Pan, Chengzeng Zhou, Meilu Zhao, Yichao Ge

Chem Biodivers· August 2025

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Targeting LIF With Cyclovirobuxine D to Suppress Tumor Progression via LIF/p38MAPK/p62-Modulated Mitophagy in Hepatocellular Carcinoma.
Yingying Shao, Di Lu, Wenke Jin, Sibao Chen, Lifeng Han, Leilei Fu

MedComm (2020)· June 2025

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N-Heterocyclic Carbene Organocatalysis Enabled Modular Synthesis of Fluorinated Isoflavonoids to Suppress Proliferation and Migration in Breast Cancer Cells.
Yan-Qing Liu, Lei-Lei Fu, Long-Hai Hong, Xin-Xin Kou, Xiang Zhang

Adv Sci (Weinh)· April 2025

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Editorial: Discovery of small molecule lead compounds: a driving force to unravel new anti-cancer targets and mechanisms, Volume II.
Yan Zhang, Leilei Fu, Muhammad Umer Farooq Awan, Yinu Wang

Front Pharmacol· December 2024

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Targeting eukaryotic elongation factor 2 kinase (eEF2K) with small-molecule inhibitors for cancer therapy.
Huiping Wang, Wenke Jin, Zixiang Li, Chuanxin Guo, Lan Zhang, Leilei Fu

Drug Discov Today· October 2024

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Targeting PI3K family with small-molecule inhibitors in cancer therapy: current clinical status and future directions.
Hongyao Li, Xiang Wen, Yueting Ren, Zhichao Fan, Jin Zhang, Leilei Fu

Mol Cancer· August 2024

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Deciphering chemotherapy resistance: a novel apoptosis protein profile analysis in stage II colorectal cancer.
Zixiang Li, Leilei Fu

BMJ Oncol· August 2024

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2-APQC, a small-molecule activator of Sirtuin-3 (SIRT3), alleviates myocardial hypertrophy and fibrosis by regulating mitochondrial homeostasis.
Fu Peng, Minru Liao, Wenke Jin, Wei Liu, Zixiang Li, Leilei Fu

Signal Transduct Target Ther· May 2024

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Mitochondrial Sirtuins in Cancer: A Revisited Review from Molecular Mechanisms to Therapeutic Strategies.
Hui Shen, Wei Ma, Yue Hu, Yuan Liu, Yaowen Song, Leilei Fu

Theranostics· May 2024

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Flubendazole Enhances the Inhibitory Effect of Paclitaxel via HIF1α/PI3K/AKT Signaling Pathways in Breast Cancer.
Yuxin Zhou, Minru Liao, Zixiang Li, Jing Ye, Lifeng Wu, Leilei Fu

Int J Mol Sci· October 2023

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Targeting VPS34 in autophagy: An update on pharmacological small-molecule compounds.
Yuan Liu, Qilin Yang, Siwei Chen, Zixiang Li, Leilei Fu

Eur J Med Chem· August 2023

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Dual identity of tumor-associated macrophage in regulated cell death and oncotherapy.
Yingying Shao, Yu Wang, Ranran Su, Weiling Pu, Sibao Chen, Leilei Fu

Heliyon· July 2023

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CRISPR/Cas genome editing in triple negative breast cancer: Current situation and future directions.
Leilei Fu, Zixiang Li, Yueting Ren, Haiyang Yu, Bo Liu

Biochem Pharmacol· March 2023

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Editorial: Discovery of small molecule lead compounds: A driving force to unravel new anticancer targets and mechanisms.
Yan Zhang, Leilei Fu, Muhammad Umer Farooq Awan

Front Oncol· February 2023

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Inhibiting Sodium Taurocholate Cotransporting Polypeptide in HBV-Related Diseases: From Biological Function to Therapeutic Potential.
Siwei Chen, Lan Zhang, Yi Chen, Leilei Fu

J Med Chem· October 2022

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Targeting Extracellular Signal-Regulated Protein Kinase 1/2 (ERK1/2) in Cancer: An Update on Pharmacological Small-Molecule Inhibitors.
Leilei Fu, Siwei Chen, Gu He, Yi Chen, Bo Liu

J Med Chem· October 2022

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Targeting autophagy in colorectal cancer: An update on pharmacological small-molecule compounds.
Zixiang Li, Wen Si, Wenke Jin, Zhaoxin Yuan, Yi Chen, Leilei Fu

Drug Discov Today· August 2022

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Regulated cell death (RCD) in cancer: key pathways and targeted therapies.
Fu Peng, Minru Liao, Rui Qin, Shiou Zhu, Cheng Peng, Leilei Fu

Signal Transduct Target Ther· August 2022

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AMTDB: A comprehensive database of autophagic modulators for anti-tumor drug discovery.
Jiahui Fu, Lifeng Wu, Gaoyong Hu, Qiqi Shi, Ruodi Wang, Leilei Fu

Front Pharmacol· August 2022

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Two New Alkaloids from the Marine-Derived Fungus Penicillium sp. LSH-3-1.
Sihui Li, Yihan Ma, Lixia Wang, Donghe Lan, Leilei Fu

Chem Biodivers· June 2022

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Flubendazole induces mitochondrial dysfunction and DRP1-mediated mitophagy by targeting EVA1A in breast cancer.
Yongqi Zhen, Zhaoxin Yuan, Jiahui Zhang, Yao Chen, Yuning Fu, Leilei Fu

Cell Death Dis· April 2022

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Solamargine induces hepatocellular carcinoma cell apoptosis and autophagy via inhibiting LIF/miR-192-5p/CYR61/Akt signaling pathways and eliciting immunostimulatory tumor microenvironment.
Shuangshuang Yin, Wenke Jin, Yuling Qiu, Leilei Fu, Tao Wang

J Hematol Oncol· March 2022

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