Publications by authors named "Len Dally"

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Development of a Kinetic ELISA and Reactive B Cell Frequency Assay to Detect Respiratory Syncytial Virus Pre-Fusion F Protein-Specific Immune Responses in Infants.
Stephanie L Rolsma, Sandra M Yoder, Rachel S Nargi, Eric Brady, Natalia Jimenez-Truque, Len Dally

J Pediatric Infect Dis Soc· May 2023

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Performance of International AIDS Vaccine Initiative African clinical research laboratories in standardised ELISpot and peripheral blood mononuclear cell processing in support of HIV vaccine clinical trials.
Robert K Langat, Bashir Farah, Jackton Indangasi, Simon Ogola, Gloria Omosa-Manyonyi, Len Dally

Afr J Lab Med· February 2021

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Acceptability and tolerability of repeated intramuscular electroporation of Multi-antigenic HIV (HIVMAG) DNA vaccine among healthy African participants in a phase 1 randomized controlled trial.
Juliet Mpendo, Gaudensia Mutua, Annet Nanvubya, Omu Anzala, Julien Nyombayire, Len Dally

PLoS One· August 2020

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Safety and immunogenicity of a parenteral trivalent P2-VP8 subunit rotavirus vaccine: a multisite, randomised, double-blind, placebo-controlled trial.
Michelle J Groome, Lee Fairlie, Julie Morrison, Alan Fix, Anthonet Koen, Len Dally

Lancet Infect Dis· July 2020

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Immunogenicity and Viral Shedding of Russian-Backbone, Seasonal, Trivalent, Live, Attenuated Influenza Vaccine in a Phase II, Randomized, Placebo-Controlled Trial Among Preschool-Aged Children in Urban Bangladesh.
Kristen D C Lewis, Justin R Ortiz, Mohammed Z Rahman, Min Z Levine, Larisa Rudenko, Len Dally

Clin Infect Dis· August 2019

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Adeno-associated virus vectored immunoprophylaxis to prevent HIV in healthy adults: a phase 1 randomised controlled trial.
Frances H Priddy, David J M Lewis, Huub C Gelderblom, Hana Hassanin, Claire Streatfield, Len Dally

Lancet HIV· April 2019

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Live attenuated enterotoxigenic Escherichia coli (ETEC) vaccine with dmLT adjuvant protects human volunteers against virulent experimental ETEC challenge.
Clayton Harro, A Louis Bourgeois, David Sack, Richard Walker, Barbara DeNearing, Len Dally

Vaccine· March 2019

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Safety and immunogenicity of a pentavalent meningococcal conjugate vaccine containing serogroups A, C, Y, W, and X in healthy adults: a phase 1, single-centre, double-blind, randomised, controlled study.
Wilbur H Chen, Kathleen M Neuzil, C Rebecca Boyce, Marcela F Pasetti, Mardi K Reymann, Len Dally

Lancet Infect Dis· October 2018

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Impact of lower challenge doses of enterotoxigenic Escherichia coli on clinical outcome, intestinal colonization and immune responses in adult volunteers.
Subhra Chakraborty, Clayton Harro, Barbara DeNearing, Jessica Brubaker, Sean Connor, Len Dally

PLoS Negl Trop Dis· April 2018

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Safety and immunogenicity of a parenteral P2-VP8-P[8] subunit rotavirus vaccine in toddlers and infants in South Africa: a randomised, double-blind, placebo-controlled trial.
Michelle J Groome, Anthonet Koen, Alan Fix, Nicola Page, Lisa Jose, Len Dally

Lancet Infect Dis· August 2017

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A Phase 1 Human Immunodeficiency Virus Vaccine Trial for Cross-Profiling the Kinetics of Serum and Mucosal Antibody Responses to CN54gp140 Modulated by Two Homologous Prime-Boost Vaccine Regimens.
Sven Kratochvil, Paul F McKay, Jakub T Kopycinski, Cynthia Bishop, Peter John Hayes, Len Dally

Front Immunol· May 2017

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Cryopreservation-related loss of antigen-specific IFNγ producing CD4 T-cells can skew immunogenicity data in vaccine trials: Lessons from a malaria vaccine trial substudy.
Tom Ford, Claire Wenden, Alison Mbekeani, Len Dally, Josephine H Cox

Vaccine· April 2017

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A Comparative Phase I Study of Combination, Homologous Subtype-C DNA, MVA, and Env gp140 Protein/Adjuvant HIV Vaccines in Two Immunization Regimes.
Sarah Joseph, Killian Quinn, Aldona Greenwood, Alethea V Cope, Paul F McKay, Len Dally

Front Immunol· February 2017

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First-in-Human Evaluation of the Safety and Immunogenicity of an Intranasally Administered Replication-Competent Sendai Virus-Vectored HIV Type 1 Gag Vaccine: Induction of Potent T-Cell or Antibody Responses in Prime-Boost Regimens.
Julien Nyombayire, Omu Anzala, Brian Gazzard, Etienne Karita, Philip Bergin, Len Dally

J Infect Dis· January 2017

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Broad HIV-1 inhibition in vitro by vaccine-elicited CD8(+) T cells in African adults.
Gaudensia Mutua, Bashir Farah, Robert Langat, Jackton Indangasi, Simon Ogola, Len Dally

Mol Ther Methods Clin Dev· September 2016

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A Phase I Double Blind, Placebo-Controlled, Randomized Study of the Safety and Immunogenicity of Electroporated HIV DNA with or without Interleukin 12 in Prime-Boost Combinations with an Ad35 HIV Vaccine in Healthy HIV-Seronegative African Adults.
Juliet Mpendo, Gaudensia Mutua, Julien Nyombayire, Rosine Ingabire, Annet Nanvubya, Len Dally

PLoS One· May 2016

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Evaluation of the Safety, Tolerability, and Immunogenicity of an Oral, Inactivated Whole-Cell Shigella flexneri 2a Vaccine in Healthy Adult Subjects.
Subhra Chakraborty, Clayton Harro, Barbara DeNearing, Jay Bream, Nicole Bauers, Len Dally

Clin Vaccine Immunol· April 2016

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Assessment of the Safety and Immunogenicity of 2 Novel Vaccine Platforms for HIV-1 Prevention: A Randomized Trial.
Lindsey R Baden, Etienne Karita, Gaudensia Mutua, Linda-Gail Bekker, Glenda Gray, Len Dally

Ann Intern Med· March 2016

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A Phase I Double Blind, Placebo-Controlled, Randomized Study of the Safety and Immunogenicity of an Adjuvanted HIV-1 Gag-Pol-Nef Fusion Protein and Adenovirus 35 Gag-RT-Int-Nef Vaccine in Healthy HIV-Uninfected African Adults.
Gloria Omosa-Manyonyi, Juliet Mpendo, Eugene Ruzagira, William Kilembe, Elwyn Chomba, Len Dally

PLoS One· February 2016

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Use of ChAd3-EBO-Z Ebola virus vaccine in Malian and US adults, and boosting of Malian adults with MVA-BN-Filo: a phase 1, single-blind, randomised trial, a phase 1b, open-label and double-blind, dose-escalation trial, and a nested, randomised, double-blind, placebo-controlled trial.
Milagritos D Tapia, Samba O Sow, Kirsten E Lyke, Fadima Cheick Haidara, Fatoumata Diallo, Len Dally

Lancet Infect Dis· January 2016

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Safety and immunogenicity of a parenterally administered rotavirus VP8 subunit vaccine in healthy adults.
Alan D Fix, Clayton Harro, Monica McNeal, Len Dally, Jorge Flores

Vaccine· July 2015

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Long-term follow-up of study participants from prophylactic HIV vaccine clinical trials in Africa.
Claudia Schmidt, Walter Jaoko, Gloria Omosa-Manyonyi, Pontiano Kaleebu, Juliet Mpendo, Len Dally

Hum Vaccin Immunother· March 2015

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Safety and immunogenicity of DNA and MVA HIV-1 subtype C vaccine prime-boost regimens: a phase I randomised Trial in HIV-uninfected Indian volunteers.
Sanjay Mehendale, Madhuri Thakar, Seema Sahay, Makesh Kumar, Ashwini Shete, Len Dally

PLoS One· August 2013

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Safety and immunogenicity of DNA prime and modified vaccinia ankara virus-HIV subtype C vaccine boost in healthy adults.
Peter Hayes, Jill Gilmour, Andrea von Lieven, Dilbinder Gill, Lorna Clark, Len Dally

Clin Vaccine Immunol· March 2013

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Measuring human T cell responses in blood and gut samples using qualified methods suitable for evaluation of HIV vaccine candidates in clinical trials.
Harry Kaltsidis, Hannah Cheeseman, Jakub Kopycinski, Ambreen Ashraf, Michelle Cashin Cox, Len Dally

J Immunol Methods· July 2011

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